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ReactionsRhea and Human-GEM, by subsystem
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Reference

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

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Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSourceClear

Reactions

7,301–7,350 of 18,558 reactions from Rhea

Co(I)-[dimethylamine-specific corrinoid protein] + dimethylamine + H(+) = methyl-Co(III)-[dimethylamine-specific corrinoid protein] + methylamine
Direction not assertedBalance undeterminableRhea 41175
1-hexadecanoyl-2-(9-oxononanoyl)-sn-glycero-3-phosphocholine + H2O = 9-oxononanoate + 1-hexadecanoyl-sn-glycero-3-phosphocholine + H(+)
Left to rightBalancedRhea 41179
1-O-octadecyl-2-acetyl-sn-glycero-3-phosphocholine + H2O = 1-O-octadecyl-sn-glycero-3-phosphocholine + acetate + H(+)
Left to rightBalancedRhea 41183
1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phospho-L-serine + H2O = 2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phospho-L-serine + hexadecanoate + H(+)
Left to rightBalancedRhea 41187
1-hexadecanoyl-2-propionyl-sn-glycero-3-phosphocholine + H2O = propanoate + 1-hexadecanoyl-sn-glycero-3-phosphocholine + H(+)
Left to rightBalancedRhea 41191
1-hexadecanoyl-2-butanoyl-sn-glycero-3-phosphocholine + H2O = butanoate + 1-hexadecanoyl-sn-glycero-3-phosphocholine + H(+)

→ Left to right

Balanced

Rhea 41195

1-hexadecanoyl-2-pentanoyl-sn-glycero-3-phosphocholine + H2O = pentanoate + 1-hexadecanoyl-sn-glycero-3-phosphocholine + H(+)

Left to rightBalancedRhea 41199

1-hexadecanoyl-2-acetyl-sn-glycero-3-phosphocholine + H2O = 1-hexadecanoyl-sn-glycero-3-phosphocholine + acetate + H(+)

Left to rightBalancedRhea 41203

1-acyl-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serine + H2O = 2-(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serine + a fatty acid + H(+)

Direction not assertedBalance undeterminableRhea 41207

(indol-3-yl)acetate + NADH + O2 + H(+) = 2-hydroxy-(1H-indol-3-yl)acetate + NAD(+) + H2O

Direction not assertedBalancedRhea 41211

1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phospho-(1D-myo-inositol) + H2O = 1-octadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol) + (5Z,8Z,11Z,14Z)-eicosatetraenoate + H(+)

Left to rightBalancedRhea 41215

1,2-di-(9Z-octadecenoyl)-sn-glycerol + H2O = 1-(9Z-octadecenoyl)-sn-glycerol + (9Z)-octadecenoate + H(+)

Left to rightBalancedRhea 41219

1,2-dihexadecanoyl-sn-glycero-3-phosphocholine + H2O = 1-hexadecanoyl-sn-glycero-3-phosphocholine + hexadecanoate + H(+)

Left to rightBalancedRhea 41223

(S)-4-hydroxymandelate + O2 = 4-hydroxyphenylglyoxylate + H2O2

Direction not assertedBalancedRhea 41227

1-hexadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + H2O = (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + 1-hexadecanoyl-sn-glycero-3-phosphocholine + H(+)

Left to rightBalancedRhea 41231

a N-[omega-(9Z,12Z)-octadecadienoyloxy]-acylsphin-4E-enine + O2 = a N-[omega-(9R)-hydroperoxy-(10E,12Z)-octadecadienoyloxy]-acylsphin-4E-enine

Left to rightBalance undeterminableRhea 41239

a N-[omega-(9R)-hydroperoxy-(10E,12Z)-octadecadienoyloxy]-acylsphin-4E-enine = a N-[omega-(9R,10R)-epoxy-(13R)-hydroxy-(11E)-octadecenoyloxy]-acylsphing-4E-enine

Left to rightBalance undeterminableRhea 41243

(5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 = 9R-hydroperoxy(5Z,7E,11Z,14Z)-eicosatetraenoate

Direction not assertedBalancedRhea 41247

(5S)-hydroperoxy-(6E,8Z,11Z,14Z)-eicosatetraenoate = 7R-hydroxy-5S,6S-epoxy-(8Z,11Z,14Z)-eicosatrienoate

Left to rightBalancedRhea 41251

1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphate + H2O = 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycerol + phosphate

Left to rightBalancedRhea 41255

L-tryptophan = (E)-3-(indol-3-yl)acrylate + NH4(+)

Direction not assertedBalancedRhea 41259

prostaglandin A1 + NAD(+) = 15-oxo-prostaglandin A1 + NADH + H(+)

Left to rightBalancedRhea 41263

N-(15Z-tetracosenoyl)-sphing-4-enine + H2O = (15Z)-tetracosenoate + sphing-4-enine

ReversibleBalancedRhea 41267

1-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-2-O-hexadecyl-sn-glycero-3-phosphocholine + H2O = 2-O-hexadecyl-sn-glycero-3-phosphocholine + (5Z,8Z,11Z,14Z)-eicosatetraenoate + H(+)

Left to rightBalancedRhea 41271

N-eicosanoyl-sphing-4-enine + H2O = eicosanoate + sphing-4-enine

Left to rightBalancedRhea 41275

N-octadecanoylsphing-4-enine + H2O = sphing-4-enine + octadecanoate

ReversibleBalancedRhea 41279

N-tetracosanoyl-sphing-4-enine + H2O = tetracosanoate + sphing-4-enine

Left to rightBalancedRhea 41283

N-tetradecanoylsphing-4-enine + H2O = sphing-4-enine + tetradecanoate

ReversibleBalancedRhea 41287

N-dodecanoylsphing-4-enine + H2O = dodecanoate + sphing-4-enine

ReversibleBalancedRhea 41291

N-(hexanoyl)sphing-4-enine + H2O = hexanoate + sphing-4-enine

Left to rightBalancedRhea 41295

N-(9Z-octadecenoyl)-sphing-4-enine + H2O = sphing-4-enine + (9Z)-octadecenoate

ReversibleBalancedRhea 41299

N-dodecanoyl-(4R)-hydroxysphinganine + H2O = (4R)-hydroxysphinganine + dodecanoate

Right to leftBalancedRhea 41303

1-octadecanoyl-2-(9Z,12Z,15Z-octadecatrienoyl)-sn-glycero-3-phosphocholine + H2O = (9Z,12Z,15Z)-octadecatrienoate + 1-octadecanoyl-sn-glycero-3-phosphocholine + H(+)

Left to rightBalancedRhea 41307

1-O-methyl-(5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 = 1-O-methyl (5Z,8Z,10E,12R,14Z)-hydroperoxyiecosatetraenoate

Left to rightBalancedRhea 41311

1-O-methyl-(5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 = 1-O-methyl-(12S)-hydroperoxy-(5Z,8Z,10E,14Z)-eicosatetraenoate

Direction not assertedBalancedRhea 41315

1-O-(9Z)-octadecenoyl-2-O-acetyl-sn-glycero-3-phosphocholine + H2O = 2-acetyl-sn-glycero-3-phosphocholine + (9Z)-octadecenoate + H(+)

Left to rightBalancedRhea 41320

(5Z,8Z,11Z)-eicosatrienoate + O2 = (12S)-hydroperoxy-(5Z,8Z,10E)-eicosatrienoate

Left to rightBalancedRhea 41324

(8Z,11Z,14Z)-eicosatrienoate + O2 = (12S)-hydroperoxy-(8Z,10E,14Z)-eicosatrienoate

Left to rightBalancedRhea 41328

(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + O2 = (14S)-hydroperoxy-(4Z,7Z,10Z,12E,16Z,19Z)-docosahexaenoate

Left to rightBalancedRhea 41332

(5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 = (12R)-hydroperoxy-(5Z,8Z,10E,14Z)-eicosatetraenoate

Left to rightBalancedRhea 41336

(6Z,9Z,12Z)-octadecatrienoate + O2 = 10R-hydroperoxy-(6Z,8E,12Z)-octadecatrienoate

Left to rightBalancedRhea 41340

(5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate + O2 = (5Z,7Z,8Z,10E,14Z,17Z)-12-hydroperoxyeicosapentaenoate

Left to rightBalancedRhea 41344

1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphoethanolamine + H2O = 2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphoethanolamine + hexadecanoate + H(+)

Left to rightBalancedRhea 41348

a 1-acyl-sn-glycero-3-phospho-(1D-myo-inositol) + 1-hexadecanoyl-sn-glycero-3-phosphocholine = a 1-acyl-2-hexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol) + sn-glycerol 3-phosphocholine

Left to rightBalance undeterminableRhea 41352

bacteriochlorophyll a + 3 NADP(+) = geranylgeranyl-bacteriochlorophyllide a + 3 NADPH + 3 H(+)

Direction not assertedBalancedRhea 41356

1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + 1,2-dihexadecanoyl-sn-glycero-3-phosphocholine = hexadecanoyl-sn-glycero-3-phosphocholine + N-hexadecanoyl-1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + H(+)

Left to rightBalancedRhea 41360

1,2-dihexadecanoyl-sn-glycero-3-phosphocholine + a 2-acyl-sn-glycero-3-phosphocholine = a 1-hexadecanoyl-2-acyl-sn-glycero-3-phosphocholine + 2-hexadecanoyl-sn-glycero-3-phosphocholine

Left to rightBalance undeterminableRhea 41364

1-O-tetradecyl-2-acetyl-sn-glycero-3-phosphocholine + H2O = 1-O-tetradecyl-sn-glycero-3-phosphocholine + acetate + H(+)

Left to rightBalancedRhea 41368

1-O-dodecyl-2-acetyl-sn-glycero-3-phosphocholine + H2O = 1-O-dodecyl-sn-glycero-3-phosphocholine + acetate + H(+)

Left to rightBalancedRhea 41372

1-O-decyl-2-acetyl-sn-glycero-3-phosphocholine + H2O = 1-O-decyl-sn-glycero-3-phosphocholine + acetate + H(+)

Left to rightBalancedRhea 41376

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