Skip to content

Reference

Evidence

CompoundsSubstances with curated findings
OutcomesMeasured endpoints
ProteinsTransporters and enzymes
InteractionsPairs that share biology
PapersEvery paper a finding cites
ArticlesReadings of the evidence

Chemistry

ReactionsRhea and Human-GEM, by subsystem
ReachWhat a compound can become

Reference layer

PathwaysReactions grouped under one name
ProcessesWhat proteins are annotated as doing
AnatomyTissues, by what is expressed there
Cell typesCells, by what is expressed there
OrganismsSpecies a compound is prepared from
MaterialsSubstances that are not one molecule
AssessmentsRegulatory determinations, transcribed
DiseasesFeatures, genes, and where each sits

Atlas Graph Twin Access

Search the graph

Reference

Evidence

Compounds
Outcomes
Proteins
Interactions
Papers
Articles

Chemistry

Reactions
Reach

Reference layer

Pathways
Processes
Anatomy
Cell types
Organisms
Materials
Assessments
Diseases

Atlas Graph Twin Access

Loading the page.

Catalyst

Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

The graph

Compounds
Outcomes
Proteins
Atlas
Interactions
Papers
Articles
Graph
Search

Reference layer

Pathways
Processes
Anatomy
Cell types
Organisms
Materials
Assessments
Diseases
Reactions
Reach

How it works

Mission
Method
Twin
How to read the evidence
Sources and licences

Build on it

Access
In your assistant
For agents
Query the graph
Bulk export

A reference for what the literature reports. Not medical advice.

© 2026 CatalystPrivacy TermsReference data under the licences listed on the attribution page.

Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSourceClear

Reactions

7,051–7,100 of 18,558 reactions from Rhea

dodecanoyl-CoA + O2 = (2E)-dodecenoyl-CoA + H2O2
Left to rightBalancedRhea 40171
octanoyl-CoA + O2 = (2E)-octenoyl-CoA + H2O2
Left to rightBalancedRhea 40175
decanoyl-CoA + O2 = (2E)-decenoyl-CoA + H2O2
Left to rightBalancedRhea 40179
tetradecanoyl-CoA + O2 = (2E)-tetradecenoyl-CoA + H2O2
Left to rightBalancedRhea 40183
(2E)-octenoyl-CoA + H2O = (3R)-hydroxyoctanoyl-CoA
Left to rightBalancedRhea 40187
(3R)-hydroxyoctanoyl-CoA + NAD(+) = 3-oxooctanoyl-CoA + NADH + H(+)
Left to rightBalancedRhea 40191
(9Z)-hexadecenoyl-CoA + 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate = 1-(9Z-octadecenoyl)-2-(9Z-hexadecenoyl)-sn-glycero-3-phosphate + CoA
Left to right

→

Balanced

Rhea 40195

hexadecanoate + reduced [NADPH--hemoprotein reductase] + O2 = 16-hydroxyhexadecanoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Left to rightBalance undeterminableRhea 40199

tetradecanoate + reduced [NADPH--hemoprotein reductase] + O2 = 14-hydroxytetradecanoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Left to rightBalance undeterminableRhea 40203

(2E)-tetradecenedioyl-CoA + H2O = (3S)-hydroxytetradecanedioyl-CoA

Direction not assertedBalancedRhea 40207

(3S)-hydroxytetradecanedioyl-CoA + NAD(+) = 3-oxotetradecanedioyl-CoA + NADH + H(+)

Direction not assertedBalancedRhea 40211

FADH2 + O2 = FAD + H2O2 + H(+)

Direction not assertedBalancedRhea 40215

malonyl-CoA + H2O = malonate + CoA + H(+)

Left to rightBalancedRhea 40219

4,8-dimethylnonanoyl-CoA + H2O = 4,8-dimethylnonanoate + CoA + H(+)

Left to rightBalancedRhea 40223

desulfo-A47934 + 3'-phosphoadenylyl sulfate = A47934 + adenosine 3',5'-bisphosphate + H(+)

Direction not assertedBalancedRhea 40227

(25R)-5beta-cholestane-3alpha,7alpha,12alpha,26-tetrol + 2 reduced [adrenodoxin] + O2 + 2 H(+) = (25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-al + 2 oxidized [adrenodoxin] + 2 H2O

Left to rightBalance undeterminableRhea 40231

coenzyme B + coenzyme M + fumarate = coenzyme M-coenzyme B heterodisulfide + succinate

Direction not assertedBalancedRhea 40235

dodecanedioate + ATP + CoA = dodecanedioyl-CoA + AMP + diphosphate

Direction not assertedBalancedRhea 40239

(3R)-hydroxyhexadecanoyl-CoA + NAD(+) = 3-oxohexadecanoyl-CoA + NADH + H(+)

Left to rightBalancedRhea 40243

rhodomycin D + H2O = 10-carboxy-13-deoxycarminomycin + methanol + H(+)

Direction not assertedBalancedRhea 40247

4-O-methylrhodomycin D + H2O = 10-carboxy-13-deoxydaunorubicin + methanol + H(+)

Direction not assertedBalancedRhea 40251

(2E)-hexadecenedioyl-CoA + H2O = (3R)-hydroxyhexadecanedioyl-CoA

Left to rightBalancedRhea 40255

(2E)-hexadecenedioyl-CoA + H2O = (3S)-hydroxyhexadecanedioyl-CoA

Left to rightBalancedRhea 40259

(3R)-hydroxyhexadecanedioyl-CoA + NAD(+) = 3-oxohexadecanedioyl-CoA + NADH + H(+)

Left to rightBalancedRhea 40263

(3S)-hydroxyhexadecanedioyl-CoA + NAD(+) = 3-oxohexadecanedioyl-CoA + NADH + H(+)

Left to rightBalancedRhea 40267

tetradecanedioyl-CoA + O2 = (2E)-tetradecenedioyl-CoA + H2O2

Direction not assertedBalancedRhea 40271

hexadecanedioyl-CoA + O2 = (2E)-hexadecenedioyl-CoA + H2O2

Left to rightBalancedRhea 40275

dodecanoyl-CoA + (R)-carnitine = O-dodecanoyl-R-carnitine + CoA

Direction not assertedBalancedRhea 40279

hexadecanedioyl-CoA + (R)-carnitine = O-hexadecanedioyl-L-carnitine + CoA

Direction not assertedBalancedRhea 40283

decanedioate + ATP + CoA = decanedioyl-CoA + AMP + diphosphate

Direction not assertedBalancedRhea 40287

tetradecanedioate + ATP + CoA = tetradecanedioyl-CoA + AMP + diphosphate

Direction not assertedBalancedRhea 40291

hexadecanedioate + ATP + CoA = hexadecanedioyl-CoA + AMP + diphosphate

Direction not assertedBalancedRhea 40295

6-deoxyerythronolide B + 2 reduced [2Fe-2S]-[ferredoxin] + O2 + 2 H(+) = erythronolide B + 2 oxidized [2Fe-2S]-[ferredoxin] + H2O

Direction not assertedBalance undeterminableRhea 40299

dodecanedioyl-CoA + A = (2E)-dodecenedioyl-CoA + AH2

Direction not assertedBalancedRhea 40303

decanedioyl-CoA + A = (2E)-decenedioyl-CoA + AH2

Direction not assertedBalancedRhea 40307

hexanoyl-CoA + O2 = (2E)-hexenoyl-CoA + H2O2

Left to rightBalancedRhea 40311

glutaryl-CoA + O2 = (2E)-glutaconyl-CoA + H2O2

Left to rightBalancedRhea 40315

tetracosanoyl-CoA + O2 = (2E)-tetracosenoyl-CoA + H2O2

Left to rightBalancedRhea 40319

1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycerol + ATP = 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphate + ADP + H(+)

Left to rightBalancedRhea 40323

1,2-di-(9Z-octadecenoyl)-sn-glycerol + ATP = 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphate + ADP + H(+)

Left to rightBalancedRhea 40327

1-eicosanoyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycerol + ATP = 1-eicosanoyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphate + ADP + H(+)

Left to rightBalancedRhea 40331

1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycerol + ATP = 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphate + ADP + H(+)

Left to rightBalancedRhea 40335

1-octadecanoyl-2-(9Z,12Z)-octadecadienoyl-sn-glycerol + ATP = 1-octadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphate + ADP + H(+)

Left to rightBalancedRhea 40339

3-oxohexadecanedioyl-CoA + CoA = tetradecanedioyl-CoA + acetyl-CoA

Left to rightBalancedRhea 40343

3-oxotetradecanedioyl-CoA + CoA = dodecanedioyl-CoA + acetyl-CoA

Direction not assertedBalancedRhea 40347

1,2-di-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycerol + ATP = 1,2-di-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphate + ADP + H(+)

Left to rightBalancedRhea 40351

1,2-di-(9Z,12Z-octadecadienoyl)-sn-glycerol + ATP = 1,2-di-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphate + ADP + H(+)

Left to rightBalancedRhea 40355

1-octadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycerol + ATP = 1-octadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphate + ADP + H(+)

Left to rightBalancedRhea 40359

1-octadecanoyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phospho-1D-myo-inositol 4-phosphate + ATP = 1-octadecanoyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phospho-1D-myo-inositol 4,5-bisphosphate + ADP + H(+)

Left to rightBalancedRhea 40363

1-octadecanoyl-2-(9Z)-octadecenoyl-sn-glycero-3-phospho-1D-myo-inositol 4-phosphate + ATP = 1-octadecanoyl-2-(9Z)-octadecenoyl-sn-glycero-3-phospho-1D-myo-inositol 4,5-bisphosphate + ADP + H(+)

Left to rightBalancedRhea 40367

Page 142 of 372