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CompoundsSubstances with curated findings
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ProteinsTransporters and enzymes
InteractionsPairs that share biology
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ReactionsRhea and Human-GEM, by subsystem
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PathwaysReactions grouped under one name
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MaterialsSubstances that are not one molecule
AssessmentsRegulatory determinations, transcribed
DiseasesFeatures, genes, and where each sits

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Reference

Evidence

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Outcomes
Proteins
Interactions
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Chemistry

Reactions
Reach

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Cell types
Organisms
Materials
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Diseases

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

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Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSourceClear

Reactions

7,001–7,050 of 18,558 reactions from Rhea

2-aminobut-2-enoate = 2-iminobutanoate
Direction not assertedBalancedRhea 39967
1-aminocyclopropane-1-carboxylate = 2-aminobut-2-enoate
Direction not assertedBalancedRhea 39971
2-iminobutanoate + H2O = 2-oxobutanoate + NH4(+)
Direction not assertedBalancedRhea 39975
(+-)-pavine + S-adenosyl-L-methionine = N-methylpavine + S-adenosyl-L-homocysteine + H(+)
Direction not assertedBalancedRhea 39979
a 1,2-saturated fatty acid + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = a 2-hydroxy fatty acid + 2 Fe(III)-[cytochrome b5] + H2O
Direction not assertedBalance undeterminableRhea 39983
1,2,3-tri-(9Z-octadecenoyl)-glycerol + all-trans-retinol = all-trans-retinyl 9Z-octadecenoate + di-(9Z)-octadecenoylglycerol
Left to rightBalancedRhea 39987
(4R)-hydroxyeicosasphinganine + a fatty acyl-CoA = N-acyl-4-hydroxyeicosasphinganine + CoA + H(+)

Direction not assertedBalance undeterminableRhea 39991

an N-acylethanolamine + H2O = ethanolamine + a fatty acid

Direction not assertedBalance undeterminableRhea 39995

a sphingoid 1-phosphate = a fatty aldehyde + phosphoethanolamine

Direction not assertedBalance undeterminableRhea 39999

ent-copalyl diphosphate = (Z)-biformene + diphosphate

Direction not assertedBalancedRhea 40003

(+)-copalyl diphosphate + H2O = (+)-copalol + diphosphate

Direction not assertedBalancedRhea 40007

(+)-copalyl diphosphate + H2O = manool + diphosphate

Direction not assertedBalancedRhea 40011

(+)-copalyl diphosphate + H2O = 13-epi-manool + diphosphate

Direction not assertedBalancedRhea 40015

ent-copalyl diphosphate + H2O = (-)-ent-copalol + diphosphate

Direction not assertedBalancedRhea 40019

9alpha-copalyl diphosphate + H2O = syn-copalol + diphosphate

Direction not assertedBalancedRhea 40023

9alpha-copalyl diphosphate + H2O = (13S)-vitexifolin A + diphosphate

Direction not assertedBalancedRhea 40027

ent-copalyl diphosphate + H2O = ent-manool + diphosphate

Direction not assertedBalancedRhea 40031

N-acetyl-L-aspartate + L-glutamate + ATP = N-acetyl-L-aspartyl-L-glutamate + ADP + phosphate + H(+)

Direction not assertedBalancedRhea 40035

N-acetyl-L-aspartate + 2 L-glutamate + 2 ATP = N-acetyl-L-aspartyl-L-glutamyl-L-glutamate + 2 ADP + 2 phosphate + 2 H(+)

Direction not assertedBalancedRhea 40039

citrate + L-glutamate + ATP = beta-citrylglutamate + ADP + phosphate + H(+)

Direction not assertedBalancedRhea 40043

1,2,3-trioctanoylglycerol + H2O = 1,2-dioctanoyl-sn-glycerol + octanoate + H(+)

Left to rightBalancedRhea 40047

chorismate = 3-[(1-carboxyvinyl)-oxy]benzoate + H2O

Direction not assertedBalancedRhea 40051

1,2,3-trioctanoylglycerol + H2O = 2,3-dioctanoyl-sn-glycerol + octanoate + H(+)

Direction not assertedBalancedRhea 40055

decanoyl-CoA + H2O = decanoate + CoA + H(+)

Left to rightBalancedRhea 40059

6-oxocyclohex-1-ene-1-carbonyl-CoA + H2O = 2-hydroxy-6-oxocyclohexane-1-carbonyl-CoA

Direction not assertedBalancedRhea 40063

2-hydroxy-6-oxocyclohexane-1-carbonyl-CoA + H2O = 3-hydroxy-6-carboxyhexanoyl-CoA + H(+)

Direction not assertedBalancedRhea 40067

6-amino-6-deoxyfutalosine + H2O + H(+) = futalosine + NH4(+)

Direction not assertedBalancedRhea 40075

docosanoate + reduced [NADPH--hemoprotein reductase] + O2 = 22-hydroxydocosanoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Left to rightBalance undeterminableRhea 40079

hexacosanoate + reduced [NADPH--hemoprotein reductase] + O2 = 26-hydroxyhexacosanoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Left to rightBalance undeterminableRhea 40083

22-hydroxydocosanoate + NAD(+) = 22-oxodocosanoate + NADH + H(+)

Direction not assertedBalancedRhea 40087

26-hydroxyhexacosanoate + NAD(+) = 26-oxohexacosanoate + NADH + H(+)

Direction not assertedBalancedRhea 40091

26-oxohexacosanoate + NAD(+) + H2O = hexacosanedioate + NADH + 2 H(+)

Direction not assertedBalancedRhea 40095

1-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1'-sn-glycerol) + dodecanoyl-CoA = 1-(9Z-octadecenoyl)-2-dodecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol) + CoA

Left to rightBalancedRhea 40099

propanoyl-CoA + H2O = propanoate + CoA + H(+)

Left to rightBalancedRhea 40103

1-hexadecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol) + dodecanoyl-CoA = 1-hexadecanoyl-2-dodecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol) + CoA

Left to rightBalancedRhea 40107

butanoyl-CoA + H2O = butanoate + CoA + H(+)

Left to rightBalancedRhea 40111

hexanoyl-CoA + H2O = hexanoate + CoA + H(+)

Left to rightBalancedRhea 40115

tetradecanoyl-CoA + H2O = tetradecanoate + CoA + H(+)

Left to rightBalancedRhea 40119

an omega-hydroxy fatty acid + reduced [NADPH--hemoprotein reductase] + O2 = an omega-oxo fatty acid + oxidized [NADPH--hemoprotein reductase] + 2 H2O + H(+)

Direction not assertedBalance undeterminableRhea 40123

an omega-oxo fatty acid + reduced [NADPH--hemoprotein reductase] + O2 = a dicarboxylate + oxidized [NADPH--hemoprotein reductase] + H2O + 2 H(+)

Direction not assertedBalance undeterminableRhea 40127

(9Z)-hexadecenoyl-CoA + H2O = (9Z)-hexadecenoate + CoA + H(+)

Left to rightBalancedRhea 40131

(9Z)-tetradecenoyl-CoA + H2O = (9Z)-tetradecenoate + CoA + H(+)

Left to rightBalancedRhea 40135

(9Z)-octadecenoyl-CoA + H2O = (9Z)-octadecenoate + CoA + H(+)

Left to rightBalancedRhea 40139

(9Z,12Z)-octadecadienoyl-CoA + H2O = (9Z,12Z)-octadecadienoate + CoA + H(+)

Left to rightBalancedRhea 40143

eicosanoyl-CoA + H2O = eicosanoate + CoA + H(+)

Left to rightBalancedRhea 40147

(5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + H2O = (5Z,8Z,11Z,14Z)-eicosatetraenoate + CoA + H(+)

Left to rightBalancedRhea 40151

(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + reduced [NADPH--hemoprotein reductase] + O2 = 22-hydroxy-(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Left to rightBalance undeterminableRhea 40155

UDP-2-acetamido-2,6-dideoxy-beta-L-arabino-hex-4-ulose + NADH + H(+) = UDP-2-acetamido-2,6-dideoxy-beta-L-talose + NAD(+)

Direction not assertedBalancedRhea 40159

D-glyceraldehyde + NADP(+) + H2O = (R)-glycerate + NADPH + 2 H(+)

Direction not assertedBalancedRhea 40163

hexadecanoyl-CoA + O2 = (2E)-hexadecenoyl-CoA + H2O2

Left to rightBalancedRhea 40167

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