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CompoundsSubstances with curated findings
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ProteinsTransporters and enzymes
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ReactionsRhea and Human-GEM, by subsystem
ReachWhat a compound can become

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PathwaysReactions grouped under one name
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Reference

Evidence

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Reactions
Reach

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

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Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSourceClear

Reactions

6,751–6,800 of 18,558 reactions from Rhea

an N-acylsphing-4-enine 1-phosphate(in) = an N-acylsphing-4-enine 1-phosphate(out)
Direction not assertedBalance undeterminableTransportRhea 38955
a 2,3-saturated acyl-CoA + O2 = a (2E)-enoyl-CoA + H2O2
Left to rightBalance undeterminableRhea 38959
leukotriene C4(in) + ATP + H2O = leukotriene C4(out) + ADP + phosphate + H(+)
Left to rightBalancedTransportRhea 38963
an N-acylsphing-4-enine(in) + ATP + H2O = an N-acylsphing-4-enine(out) + ADP + phosphate + H(+)
Direction not assertedBalance undeterminableTransportRhea 38967
octadecanoyl-CoA + O2 = (2E)-octadecenoyl-CoA + H2O2
Left to rightBalancedRhea 38971
1-hexadecanoyl-sn-glycero-3-phosphocholine + H2O = 1-hexadecanoyl-sn-glycero-3-phosphate + choline + H(+)
Left to rightBalancedRhea 38975
1-octadecanoyl-sn-glycero-3-phosphocholine + H2O = 1-octadecanoyl-sn-glycero-3-phosphate + choline + H(+)

Left to rightBalancedRhea 38979

1-tetradecanoyl-sn-glycero-3-phosphocholine + H2O = 1-tetradecanoyl-sn-glycerol 3-phosphate + choline + H(+)

Left to rightBalancedRhea 38983

nonanoyl-CoA + O2 = (2E)-nonenoyl-CoA + H2O2

Direction not assertedBalancedRhea 38987

1-dodecanoyl-sn-glycero-3-phosphocholine + H2O = 1-dodecanoyl-sn-glycerol 3-phosphate + choline + H(+)

Left to rightBalancedRhea 38991

a 1-acyl-sn-glycero-3-phosphocholine + H2O = a 1-acyl-sn-glycero-3-phosphate + choline + H(+)

Left to rightBalance undeterminableRhea 38995

a 1-acyl-sn-glycero-3-phospho-L-serine + H2O = a 1-acyl-sn-glycero-3-phosphate + L-serine + H(+)

Left to rightBalance undeterminableRhea 38999

a 1-acyl-sn-glycero-3-phosphoethanolamine + H2O = a 1-acyl-sn-glycero-3-phosphate + ethanolamine + H(+)

Left to rightBalance undeterminableRhea 39003

a cholesterol ester(in) = a cholesterol ester(out)

Left to rightBalance undeterminableTransportRhea 39007

a triacyl-sn-glycerol(in) = a triacyl-sn-glycerol(out)

Left to rightBalance undeterminableTransportRhea 39011

22-oxodocosanoate + NAD(+) + H2O = docosanedioate + NADH + 2 H(+)

Direction not assertedBalancedRhea 39015

a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,5-bisphosphate) + H2O = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-5-phosphate) + phosphate

Left to rightBalance undeterminableRhea 39019

an omega-methyl fatty acid + reduced [NADPH--hemoprotein reductase] + O2 = an omega-hydroxy fatty acid + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 39023

a 1,2-diacyl-3-O-(beta-D-Glc-(1->6)-beta-D-Glc)-sn-glycerol + UDP-alpha-D-glucose = a 1,2-diacyl-3-O-(beta-D-Glc-(1->6)-beta-D-Glc-(1->6)-beta-D-Glc)-sn-glycerol + UDP + H(+)

Direction not assertedBalance undeterminableRhea 39027

a 1,2-diacyl-3-O-(beta-D-glucopyranosyl)-sn-glycerol + UDP-alpha-D-glucose = a 1,2-diacyl-3-O-(beta-D-Glc-(1->6)-beta-D-Glc)-sn-glycerol + UDP + H(+)

Direction not assertedBalance undeterminableRhea 39031

an omega-hydroxy fatty acid + NAD(+) = an omega-oxo fatty acid + NADH + H(+)

Direction not assertedBalance undeterminableRhea 39035

an omega-oxo fatty acid + NAD(+) + H2O = a dicarboxylate + NADH + 2 H(+)

Direction not assertedBalance undeterminableRhea 39039

22-oxodocosanoate + reduced [NADPH--hemoprotein reductase] + O2 = docosanedioate + oxidized [NADPH--hemoprotein reductase] + H2O + 2 H(+)

Left to rightBalance undeterminableRhea 39043

26-oxohexacosanoate + reduced [NADPH--hemoprotein reductase] + O2 = hexacosanedioate + oxidized [NADPH--hemoprotein reductase] + H2O + 2 H(+)

Left to rightBalance undeterminableRhea 39047

cholesterol(in) + ATP + H2O = cholesterol(out) + ADP + phosphate + H(+)

Left to rightBalancedTransportRhea 39051

22-hydroxydocosanoate + reduced [NADPH--hemoprotein reductase] + O2 = 22-oxodocosanoate + oxidized [NADPH--hemoprotein reductase] + 2 H2O + H(+)

Left to rightBalance undeterminableRhea 39055

26-hydroxyhexacosanoate + reduced [NADPH--hemoprotein reductase] + O2 = 26-oxohexacosanoate + oxidized [NADPH--hemoprotein reductase] + 2 H2O + H(+)

Left to rightBalance undeterminableRhea 39059

scyllo-inositol + NADP(+) = scyllo-inosose + NADPH + H(+)

Direction not assertedBalancedRhea 39063

3-oxooctanedioyl-CoA + CoA = hexanedioyl-CoA + acetyl-CoA

Direction not assertedBalancedRhea 39067

dodecanedioyl-CoA + O2 = (2E)-dodecenedioyl-CoA + H2O2

Direction not assertedBalancedRhea 39071

(2E)-dodecenedioyl-CoA + H2O = (3S)-hydroxydodecanedioyl-CoA

Direction not assertedBalancedRhea 39075

(3S)-hydroxydodecanedioyl-CoA + NAD(+) = 3-oxododecanedioyl-CoA + NADH + H(+)

Direction not assertedBalancedRhea 39079

3-oxododecanedioyl-CoA + CoA = decanedioyl-CoA + acetyl-CoA

Direction not assertedBalancedRhea 39083

decanedioyl-CoA + O2 = (2E)-decenedioyl-CoA + H2O2

Direction not assertedBalancedRhea 39087

(2E)-decenedioyl-CoA + H2O = (3S)-hydroxydecanedioyl-CoA

Direction not assertedBalancedRhea 39091

(3S)-hydroxydecanedioyl-CoA + NAD(+) = 3-oxodecanedioyl-CoA + NADH + H(+)

Direction not assertedBalancedRhea 39095

3-oxodecanedioyl-CoA + CoA = octanedioyl-CoA + acetyl-CoA

Direction not assertedBalancedRhea 39099

sitosterol(in) + ATP + H2O = sitosterol(out) + ADP + phosphate + H(+)

Left to rightBalancedTransportRhea 39103

(5S)-hydroperoxy-(18S)-hydroxy-(6E,8Z,11Z,14Z,16E)-eicosapentaenoate = (5S,6S)-epoxy-(18S)-hydroxy-(7E,9E,11Z,14Z,16E)-eicosapentaenoate + H2O

Left to rightBalancedRhea 39107

4-hydroxy-2,5-dimethyl-furan-3(2H)-one + NADP(+) = 4-hydroxy-5-methyl-2-methylenefuran-3(2H)-one + NADPH + H(+)

Direction not assertedBalancedRhea 39111

4-hydroxy-2,5-dimethyl-furan-3(2H)-one + NAD(+) = 4-hydroxy-5-methyl-2-methylenefuran-3(2H)-one + NADH + H(+)

Direction not assertedBalancedRhea 39115

(6Z,9Z,12Z,15Z,18Z,21Z)-tetracosahexaenoyl-CoA + O2 = (2E,6Z,9Z,12Z,15Z,18Z,21Z)-tetracosaheptaenoyl-CoA + H2O2

Left to rightBalancedRhea 39119

(2E,6Z,9Z,12Z,15Z,18Z,21Z)-tetracosaheptaenoyl-CoA + H2O = (S)-3-hydroxy-(6Z,9Z,12Z,15Z,18Z,21Z)-tetracosahexaenoyl-CoA

Direction not assertedBalancedRhea 39123

(S)-3-hydroxy-(6Z,9Z,12Z,15Z,18Z,21Z)-tetracosahexaenoyl-CoA + NAD(+) = 3-oxo-(6Z,9Z,12Z,15Z,18Z,21Z)-tetracosahexaenoyl-CoA + NADH + H(+)

Direction not assertedBalancedRhea 39127

3-oxo-(6Z,9Z,12Z,15Z,18Z,21Z)-tetracosahexaenoyl-CoA + CoA = (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA + acetyl-CoA

Left to rightBalancedRhea 39131

(6Z,9Z,12Z,15Z,18Z)-tetracosapentaenoyl-CoA + O2 = (2E,6Z,9Z,12Z,15Z,18Z)-tetracosahexaenoyl-CoA + H2O2

Left to rightBalancedRhea 39135

(2E,6Z,9Z,12Z,15Z,18Z)-tetracosahexaenoyl-CoA + H2O = (S)-3-hydroxy-(6Z,9Z,12Z,15Z,18Z)-tetracosapentaenoyl-CoA

Direction not assertedBalancedRhea 39139

(S)-3-hydroxy-(6Z,9Z,12Z,15Z,18Z)-tetracosapentaenoyl-CoA + NAD(+) = 3-oxo-(6Z,9Z,12Z,15Z,18Z)-tetracosapentaenoyl-CoA + NADH + H(+)

Direction not assertedBalancedRhea 39143

3-oxo-(6Z,9Z,12Z,15Z,18Z)-tetracosapentaenoyl-CoA + CoA = (4Z,7Z,10Z,13Z,16Z)-docosapentaenoyl-CoA + acetyl-CoA

Left to rightBalancedRhea 39147

3-oxooctadecanoyl-CoA + NADPH + H(+) = (3R)-hydroxyoctadecanoyl-CoA + NADP(+)

Direction not assertedBalancedRhea 39151

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