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Evidence

CompoundsSubstances with curated findings
OutcomesMeasured endpoints
ProteinsTransporters and enzymes
InteractionsPairs that share biology
PapersEvery paper a finding cites
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ReactionsRhea and Human-GEM, by subsystem
ReachWhat a compound can become

Reference layer

PathwaysReactions grouped under one name
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AnatomyTissues, by what is expressed there
Cell typesCells, by what is expressed there
OrganismsSpecies a compound is prepared from
MaterialsSubstances that are not one molecule
AssessmentsRegulatory determinations, transcribed
DiseasesFeatures, genes, and where each sits

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Reference

Evidence

Compounds
Outcomes
Proteins
Interactions
Papers
Articles

Chemistry

Reactions
Reach

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Pathways
Processes
Anatomy
Cell types
Organisms
Materials
Assessments
Diseases

Atlas Graph Twin Access

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

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Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSourceClear

Reactions

601–650 of 18,558 reactions from Rhea

L-dopa = (E)-caffeate + NH4(+)
Direction not assertedBalancedRhea 12520
L-pipecolate + NADP(+) = Delta(1)-piperideine-2-carboxylate + NADPH + H(+)
Right to leftBalancedRhea 12524
N-acetyl-beta-D-glucosaminyl-(1->4)-[hyaluronan](n) + UDP-alpha-D-glucuronate = [hyaluronan](n+1) + UDP + H(+)
Left to rightBalance undeterminableRhea 12528
coenzyme B + methyl-coenzyme M = methane + coenzyme M-coenzyme B heterodisulfide
Direction not assertedBalancedRhea 12532
L-arogenate + H(+) = L-phenylalanine + CO2 + H2O
Direction not assertedBalancedRhea 12536
tRNA(Ala) + L-alanine + ATP = L-alanyl-tRNA(Ala) + AMP + diphosphate
Direction not assertedBalancedRhea 12540
hydrogenobyrinate + 2 L-glutamine + 2 ATP + 2 H2O = hydrogenobyrinate a,c-diamide + 2 L-glutamate + 2 ADP + 2 phosphate + 2 H(+)

Direction not assertedBalancedRhea 12544

2-cis,4-trans-xanthoxin + NAD(+) = 2-cis-(+)-abscisic aldehyde + NADH + H(+)

Direction not assertedBalancedRhea 12548

(E)-cinnamoyl-CoA + 3 malonyl-CoA + 3 H(+) = (E)-pinosylvin + 4 CO2 + 4 CoA

Direction not assertedBalancedRhea 12552

6-phospho-D-glucono-1,5-lactone + H2O = 6-phospho-D-gluconate + H(+)

Left to rightBalancedRhea 12556

hydroquinone + UDP-alpha-D-glucose = hydroquinone O-beta-D-glucopyranoside + UDP + H(+)

Direction not assertedBalancedRhea 12560

4-nitrophenol + NADH + O2 + H(+) = 4-nitrocatechol + NAD(+) + H2O

Direction not assertedBalancedRhea 12568

(R)-1-aminopropan-2-ol + adenosylcob(III)yrate + ATP = adenosylcob(III)inamide + ADP + phosphate + H(+)

Direction not assertedBalancedRhea 12572

(5R)-5-O-(beta-D-galactosyl)-5-hydroxy-L-lysyl-[collagen] + UDP-alpha-D-glucose = (5R)-5-O-[alpha-D-glucosyl-(1->2)-beta-D-galactosyl]-5-hydroxy-L-lysyl-[collagen] + UDP + H(+)

Direction not assertedBalance undeterminableRhea 12576

tauropine + NAD(+) + H2O = taurine + pyruvate + NADH + H(+)

Direction not assertedBalancedRhea 12580

16alpha-hydroxyprogesterone = 16,17-didehydroprogesterone + H2O

Direction not assertedBalancedRhea 12584

a ganglioside GM3 (d18:1(4E)) + UDP-N-acetyl-alpha-D-galactosamine = a ganglioside GM2 (d18:1(4E)) + UDP + H(+)

Left to rightBalance undeterminableRhea 12588

a CDP-1,2-diacyl-sn-glycerol + sn-glycerol 3-phosphate = a 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycero-3'-phosphate) + CMP + H(+)

Direction not assertedBalance undeterminableRhea 12593

L-phosphinothricin + acetyl-CoA = N-acetyl-L-phosphinothricin + CoA + H(+)

Direction not assertedBalancedRhea 12597

L-2-aminoadipate + 2-oxoglutarate = 2-oxoadipate + L-glutamate

Left to rightBalancedRhea 12601

D-glyceraldehyde 3-phosphate + pyruvate + H(+) = 1-deoxy-D-xylulose 5-phosphate + CO2

Direction not assertedBalancedRhea 12605

mercaptopurine + S-adenosyl-L-methionine = 6-methylthiopurine + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 12609

L-cystine + 2 glutathione = glutathione disulfide + 2 L-cysteine

Direction not assertedBalancedRhea 12613

N-acetyl-alpha-D-galactosamine + ATP = N-acetyl-alpha-D-galactosamine 1-phosphate + ADP + H(+)

Direction not assertedBalancedRhea 12617

L-aspartate + H(+) = L-alanine + CO2

Direction not assertedBalancedRhea 12621

1-O-(trans-sinapoyl)-beta-D-glucose + (S)-malate = sinapoyl (S)-malate + D-glucose

Direction not assertedBalancedRhea 12625

L-hyoscyamine + 2-oxoglutarate + O2 = (6S)-6-hydroxyhyoscyamine + succinate + CO2

Direction not assertedBalancedRhea 12629

benzoate + NADH + O2 + H(+) = (1R,6S)-1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate + NAD(+)

Direction not assertedBalancedRhea 12633

(5R)-5-hydroxy-L-lysyl-[collagen] + UDP-alpha-D-galactose = (5R)-5-O-(beta-D-galactosyl)-5-hydroxy-L-lysyl-[collagen] + UDP + H(+)

Direction not assertedBalance undeterminableRhea 12637

(2R)-3-phosphoglycerate + NAD(+) = 3-phosphooxypyruvate + NADH + H(+)

Direction not assertedBalancedRhea 12641

indole-3-pyruvate + 2 oxidized [2Fe-2S]-[ferredoxin] + CoA = (indol-3-yl)acetyl-CoA + 2 reduced [2Fe-2S]-[ferredoxin] + CO2 + H(+)

Direction not assertedBalance undeterminableRhea 12645

L-rhamnofuranose + NAD(+) = L-rhamnono-1,4-lactone + NADH + H(+)

Direction not assertedBalancedRhea 12649

(S)-malate + NAD(+) = pyruvate + CO2 + NADH

Direction not assertedBalancedRhea 12653

a (2S)-2-methylacyl-CoA = a (2R)-2-methylacyl-CoA

ReversibleBalance undeterminableRhea 12657

(R)-carnitine + hexadecanoyl-CoA = O-hexadecanoyl-(R)-carnitine + CoA

ReversibleBalancedRhea 12661

a 2-deoxystreptamine antibiotic + acetyl-CoA = an N(3)-acetyl-2-deoxystreptamine antibiotic + CoA + H(+)

Direction not assertedBalance undeterminableRhea 12665

O-phospho-L-seryl-[pyruvate dehydrogenase E1 alpha subunit] + H2O = L-seryl-[pyruvate dehydrogenase E1 alpha subunit] + phosphate

Left to rightBalance undeterminableRhea 12669

an aliphatic primary amide = an aliphatic nitrile + H2O

Direction not assertedBalance undeterminableRhea 12673

Latia luciferin + AH2 + 2 O2 = oxidized Latia luciferin + hnu + formate + A + CO2 + H2O + H(+)

Direction not assertedBalance undeterminableRhea 12677

creatinine + H2O + H(+) = N-methylhydantoin + NH4(+)

Direction not assertedBalancedRhea 12681

2 mycothiol + NADP(+) = mycothione + NADPH + H(+)

Direction not assertedBalancedRhea 12685

2 mycothiol + NAD(+) = mycothione + NADH + H(+)

Direction not assertedBalancedRhea 12689

3,4-dihydroxypyridine + O-acetyl-L-serine = 3-(3,4-dihydroxypyridin-1-yl)-L-alanine + acetate + H(+)

Direction not assertedBalancedRhea 12693

dGMP + ATP = dGDP + ADP

Direction not assertedBalancedRhea 12697

a 2'-deoxyribonucleoside 5'-triphosphate + [thioredoxin]-disulfide + H2O = a ribonucleoside 5'-triphosphate + [thioredoxin]-dithiol

Direction not assertedBalance undeterminableRhea 12701

[protein]-L-isoaspartate + S-adenosyl-L-methionine = [protein]-L-isoaspartate alpha-methyl ester + S-adenosyl-L-homocysteine

Left to rightBalance undeterminableRhea 12705

a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+)

Left to rightBalance undeterminableRhea 12709

a nucleoside 5'-phosphate + ATP = a 5'-phosphonucleoside 3'-diphosphate + AMP + H(+)

Direction not assertedBalance undeterminableRhea 12713

1D-myo-inositol 1,3,4,6-tetrakisphosphate + ATP = 1D-myo-inositol 1,3,4,5,6-pentakisphosphate + ADP + H(+)

Direction not assertedBalancedRhea 12717

S-adenosyl 3-(methylsulfanyl)propylamine + putrescine = S-methyl-5'-thioadenosine + spermidine + H(+)

Direction not assertedBalancedRhea 12721

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