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CompoundsSubstances with curated findings
OutcomesMeasured endpoints
ProteinsTransporters and enzymes
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ReactionsRhea and Human-GEM, by subsystem
ReachWhat a compound can become

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PathwaysReactions grouped under one name
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MaterialsSubstances that are not one molecule
AssessmentsRegulatory determinations, transcribed
DiseasesFeatures, genes, and where each sits

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Reference

Evidence

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Reach

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

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Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSourceClear

Reactions

6,201–6,250 of 18,558 reactions from Rhea

O-ureido-L-serine = O-ureido-D-serine
Direction not assertedBalancedRhea 36707
O-ureido-D-serine + ATP + H2O + H(+) = D-cycloserine + NH4(+) + ADP + CO2 + phosphate
Direction not assertedBalancedRhea 36711
tetracosenoyl-CoA + sphinganine = an N-tetracosenoylsphinganine + CoA + H(+)
Left to rightBalancedRhea 36715
hexacosenoyl-CoA + sphinganine = N-hexacosenoylsphinganine + CoA + H(+)
Left to rightBalancedRhea 36719
2-phenylethylamine + A + H2O = 2-phenylacetaldehyde + AH2 + NH4(+)
Direction not assertedBalancedRhea 36723
1-nitrocyclohexan + NADP(+) = 1-nitrocyclohexene + NADPH + H(+)
Direction not assertedBalancedRhea 36731
heptadecasphing-4-enine + tetracosanoyl-CoA = N-tetracosanoyl-heptadecasphing-4-enine + CoA + H(+)

Left to rightBalancedRhea 36739

tetracosenoyl-CoA + heptadecasphing-4-enine = N-tetracosenoyl-heptadecasphing-4-enine + CoA + H(+)

Direction not assertedBalancedRhea 36743

N-acetyl-alpha-D-glucosaminyl-di-trans,octa-cis-undecaprenyl diphosphate + UDP-alpha-D-galactose = beta-D-Gal-(1->3)-alpha-D-GlcNAc-di-trans,octa-cis-undecaprenyl diphosphate + UDP + H(+)

Direction not assertedBalancedRhea 36747

N-acetyl-alpha-D-glucosaminyl-di-trans,octa-cis-undecaprenyl diphosphate + UDP-alpha-D-galactose = beta-D-Gal-(1->4)-alpha-D-GlcNAc-di-trans,octa-cis-undecaprenyl diphosphate + UDP + H(+)

Direction not assertedBalancedRhea 36751

N-acetyl-alpha-D-glucosaminyl-di-trans,octa-cis-undecaprenyl diphosphate + UDP-alpha-D-glucose = beta-D-Glc-(1->3)-alpha-D-GlcNAc-di-trans,octa-cis-undecaprenyl diphosphate + UDP + H(+)

Direction not assertedBalancedRhea 36755

N-acetyl-alpha-D-galactosaminyl-di-trans,octa-cis-undecaprenyl diphosphate + UDP-N-acetyl-alpha-D-galactosamine = alpha-D-GalNAc-(1->3)-alpha-D-GalNAc-di-trans,octa-cis-undecaprenyl diphosphate + UDP + H(+)

Direction not assertedBalancedRhea 36759

alpha-D-GalNAc-(1->3)-alpha-D-GalNAc-di-trans,octa-cis-undecaprenyl diphosphate + UDP-alpha-D-galactose = beta-D-Gal-(1->3)-alpha-D-GalNAc-(1->3)-alpha-D-GalNAc-di-trans,octa-cis-undecaprenyl diphosphate + UDP + H(+)

Direction not assertedBalancedRhea 36763

2-hydroxytetracosenoyl-CoA + sphinganine = N-(2-hydroxytetracosenoyl)-sphinganine + CoA + H(+)

Left to rightBalancedRhea 36767

beta-D-Gal-(1->3)-alpha-D-GalNAc-(1->3)-alpha-D-GalNAc-di-trans,octa-cis-undecaprenyl diphosphate + GDP-beta-L-fucose = alpha-L-Fuc-(1->2)-beta-D-Gal-(1->3)-alpha-D-GalNAc-(1->3)-alpha-D-GalNAc-di-trans,octa-cis-undecaprenyl diphosphate + GDP + H(+)

Direction not assertedBalancedRhea 36771

alpha-L-Fuc-(1->2)-beta-D-Gal-(1->3)-alpha-D-GalNAc-(1->3)-alpha-D-GalNAc-di-trans,octa-cis-undecaprenyl diphosphate + UDP-alpha-D-galactose = alpha-L-Fuc-(1->2)-[alpha-D-Gal-(1->3)]-beta-D-Gal-(1->3)-alpha-D-GalNAc-(1->3)-alpha-D-GalNAc-di-trans,octa-cis-undecaprenyl diphosphate + UDP + H(+)

Direction not assertedBalancedRhea 36775

GDP-alpha-D-perosamine + 2-oxoglutarate = GDP-4-dehydro-alpha-D-rhamnose + L-glutamate

Direction not assertedBalancedRhea 36779

L-histidyl-[translation elongation factor 2] + S-adenosyl-L-methionine = 2-[(3S)-amino-3-carboxypropyl]-L-histidyl-[translation elongation factor 2] + S-methyl-5'-thioadenosine + H(+)

Direction not assertedBalance undeterminableRhea 36783

di-trans,octa-cis-undecaprenyl phosphate + UDP-N-acetyl-alpha-D-galactosamine = N-acetyl-alpha-D-galactosaminyl-di-trans,octa-cis-undecaprenyl diphosphate + UMP

Direction not assertedBalancedRhea 36787

N(omega)-hydroxy-L-arginine + H2O = hydroxyurea + L-ornithine

Direction not assertedBalancedRhea 36791

a ribonucleoside 5'-triphosphate + 2 H2O = a ribonucleoside 5'-phosphate + 2 phosphate + 2 H(+)

Left to rightBalance undeterminableRhea 36795

a ribonucleoside 5'-diphosphate + H2O = a ribonucleoside 5'-phosphate + phosphate + H(+)

Left to rightBalance undeterminableRhea 36799

2-hydroxy-2,3-dihydrogenistein = genistein + H2O + H(+)

Direction not assertedBalancedRhea 36803

octacosanoyl-CoA + malonyl-CoA + H(+) = 3-oxo-triacontanoyl-CoA + CO2 + CoA

Left to rightBalancedRhea 36807

GDP-alpha-D-perosamine + acetyl-CoA = GDP-N-acetyl-alpha-D-perosamine + CoA + H(+)

Direction not assertedBalancedRhea 36811

dTDP-alpha-D-fucose = dTDP-alpha-D-fucofuranose

Direction not assertedBalancedRhea 36815

(11Z,14Z,17Z,20Z,23Z)-hexacosapentaenoyl-CoA + malonyl-CoA + H(+) = 3-oxo-(13Z,16Z,19Z,22Z,25Z)-octacosapentaenoyl-CoA + CO2 + CoA

Left to rightBalancedRhea 36819

CDP-2,3-bis-O-(phytanyl)-sn-glycerol + 1D-myo-inositol 3-phosphate = saturated 1-archaetidyl-1D-myo-inositol 3-phosphate + CMP + H(+)

Direction not assertedBalancedRhea 36823

dioscin + 3 H2O = diosgenin + 2 L-rhamnopyranose + D-glucose

Direction not assertedBalancedRhea 36827

2 caldariellaquinol + O2 + n H(+)(in) = 2 caldariellaquinone + 2 H2O + n H(+)(out)

Direction not assertedBalance undeterminableTransportRhea 36831

1-octadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol) + (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA = 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phospho-(1D-myo-inositol) + CoA

Left to rightBalancedRhea 36835

1-octadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol) + (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoyl-CoA = 1-octadecanoyl-2-(5Z,8Z,11Z,14Z,17Z-eicosapentaenoyl)-sn-glycero-3-phospho-(1D-myo-inositol) + CoA

Direction not assertedBalancedRhea 36839

(13Z,16Z,19Z,22Z,25Z)-octacosapentaenoyl-CoA + malonyl-CoA + H(+) = 3-oxo-(15Z,18Z,21Z,24Z,27Z)-triacontapentaenoyl-CoA + CO2 + CoA

Left to rightBalancedRhea 36843

L-threonyl-[protein] + FAD = FMN-L-threonyl-[protein] + AMP + H(+)

Direction not assertedBalance undeterminableRhea 36847

(15Z,18Z,21Z,24Z,27Z)-triacontapentaenoyl-CoA + malonyl-CoA + H(+) = 3-oxo-(17Z,20Z,23Z,26Z,29Z)-dotriacontapentaenoyl-CoA + CO2 + CoA

Left to rightBalancedRhea 36851

an N-acetyl-L-cysteine-S-conjugate + H2O = an S-substituted L-cysteine + acetate

Direction not assertedBalance undeterminableRhea 36855

(17Z,20Z,23Z,26Z,29Z)-dotriacontapentaenoyl-CoA + malonyl-CoA + H(+) = 3-oxo-(19Z,22Z,25Z,28Z,31Z)-tetratriacontapentaenoyl-CoA + CO2 + CoA

Left to rightBalancedRhea 36859

(9Z)-octadecenoyl-CoA + AH2 + O2 = (9Z,12Z)-octadecadienoyl-CoA + A + 2 H2O

Direction not assertedBalancedRhea 36863

(5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O

Direction not assertedBalance undeterminableRhea 36867

(19Z,22Z,25Z,28Z,31Z)-tetratriacontapentaenoyl-CoA + malonyl-CoA + H(+) = 3-oxo-(21Z,24Z,27Z,30Z,33Z)-hexatriacontapentaenoyl-CoA + CO2 + CoA

Left to rightBalancedRhea 36871

(21Z,24Z,27Z,30Z,33Z)-hexatriacontapentaenoyl-CoA + malonyl-CoA + H(+) = 3-oxo-(23Z,26Z,29Z,32Z,35Z)-octatriacontapentaenoyl-CoA + CO2 + CoA

Left to rightBalancedRhea 36875

(8Z,11Z,14Z)-eicosatrienoyl-CoA + AH2 + O2 = (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + A + 2 H2O

Direction not assertedBalancedRhea 36879

(8Z,11Z,14Z)-eicosatrienoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (8Z,11Z,14Z,17Z)-eicosatetraenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O

Direction not assertedBalance undeterminableRhea 36883

(8Z,11Z,14Z,17Z)-eicosatetraenoyl-CoA + AH2 + O2 = (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoyl-CoA + A + 2 H2O

Direction not assertedBalancedRhea 36887

(9Z,12Z)-octadecadienoyl-CoA + AH2 + O2 = (9Z,12Z,15Z)-octadecatrienoyl-CoA + A + 2 H2O

Direction not assertedBalancedRhea 36891

(9Z,12Z,15Z)-octadecatrienoyl-CoA + AH2 + O2 = (6Z,9Z,12Z,15Z)-octadecatetraenoyl-CoA + A + 2 H2O

Direction not assertedBalancedRhea 36895

guanosine(37) in tRNA + S-adenosyl-L-methionine = N(1)-methylguanosine(37) in tRNA + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 36899

7-[(3S)-3-amino-3-carboxypropyl]wyosine(37) in tRNA(Phe) + S-adenosyl-L-methionine = 7-[(3S)-(3-amino-3-methoxycarbonyl)propyl]wyosine(37) in tRNA(Phe) + S-adenosyl-L-homocysteine

Direction not assertedBalance undeterminableRhea 36903

(11Z,14Z,17Z,20Z)-hexacosatetraenoyl-CoA + malonyl-CoA + H(+) = (13Z,16Z,19Z,22Z)-3-oxooctacosatetraenoyl-CoA + CO2 + CoA

Left to rightBalancedRhea 36907

(13Z,16Z,19Z,22Z)-octacosatetraenoyl-CoA + malonyl-CoA + H(+) = 3-oxo-(15Z,18Z,21Z,24Z)-triacontatetraenoyl-CoA + CO2 + CoA

Left to rightBalancedRhea 36911

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