Skip to content

Reference

Evidence

CompoundsSubstances with curated findings
OutcomesMeasured endpoints
ProteinsTransporters and enzymes
InteractionsPairs that share biology
PapersEvery paper a finding cites
ArticlesReadings of the evidence

Chemistry

ReactionsRhea and Human-GEM, by subsystem
ReachWhat a compound can become

Reference layer

PathwaysReactions grouped under one name
ProcessesWhat proteins are annotated as doing
AnatomyTissues, by what is expressed there
Cell typesCells, by what is expressed there
OrganismsSpecies a compound is prepared from
MaterialsSubstances that are not one molecule
AssessmentsRegulatory determinations, transcribed
DiseasesFeatures, genes, and where each sits

Atlas Graph Twin Access

Search the graph

Reference

Evidence

Compounds
Outcomes
Proteins
Interactions
Papers
Articles

Chemistry

Reactions
Reach

Reference layer

Pathways
Processes
Anatomy
Cell types
Organisms
Materials
Assessments
Diseases

Atlas Graph Twin Access

Loading the page.

Catalyst

Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

The graph

Compounds
Outcomes
Proteins
Atlas
Interactions
Papers
Articles
Graph
Search

Reference layer

Pathways
Processes
Anatomy
Cell types
Organisms
Materials
Assessments
Diseases
Reactions
Reach

How it works

Mission
Method
Twin
How to read the evidence
Sources and licences

Build on it

Access
In your assistant
For agents
Query the graph
Bulk export

A reference for what the literature reports. Not medical advice.

© 2026 CatalystPrivacy TermsReference data under the licences listed on the attribution page.

Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSourceClear

Reactions

6,151–6,200 of 18,558 reactions from Rhea

docosanoyl-CoA + malonyl-CoA + H(+) = 3-oxotetracosanoyl-CoA + CO2 + CoA
Left to rightBalancedRhea 36507
(9Z)-octadecenoyl-CoA + malonyl-CoA + H(+) = 3-oxo-(11Z)-eicosenoyl-CoA + CO2 + CoA
Left to rightBalancedRhea 36511
tetracosanoyl-CoA + malonyl-CoA + H(+) = 3-oxohexacosanoyl-CoA + CO2 + CoA
Left to rightBalancedRhea 36515
hexacosanoyl-CoA + malonyl-CoA + H(+) = 3-oxooctacosanyol-CoA + CO2 + CoA
Left to rightBalancedRhea 36519
(9Z,12Z,15Z)-octadecatrienoyl-CoA + malonyl-CoA + H(+) = (11Z,14Z,17Z)-3-oxoeicosatrienoyl-CoA + CO2 + CoA
Left to rightBalancedRhea 36523
(11Z)-eicosenoyl-CoA + malonyl-CoA + H(+) = 3-oxo-(13Z)-docosenoyl-CoA + CO2 + CoA
Left to rightBalancedRhea 36527
(13Z)-docosenoyl-CoA + malonyl-CoA + H(+) = 3-oxo-(15Z)-tetracosenoyl-CoA + CO2 + CoA

Left to rightBalancedRhea 36531

docosanoyl-CoA + sphinganine = N-docosanoylsphinganine + CoA + H(+)

Left to rightBalancedRhea 36535

sphinganine + hexadecanoyl-CoA = N-hexadecanoylsphinganine + CoA + H(+)

Left to rightBalancedRhea 36539

mycothiol S-conjugate + H2O = an N-acetyl-L-cysteine-S-conjugate + 1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside

Direction not assertedBalance undeterminableRhea 36543

sphinganine + octadecanoyl-CoA = N-(octadecanoyl)-sphinganine + CoA + H(+)

Left to rightBalancedRhea 36547

3-O-[beta-D-GalNAc-(1->3)-beta-D-GlcNAc-(1->4)-(O-6-P-alpha-D-Man)]-Thr-[protein] + CDP-L-ribitol = 3-O-[Rib-ol-P-3-beta-D-GalNAc-(1->3)-beta-D-GlcNAc-(1->4)-(O-6-P-alpha-D-Man)]-Thr-[protein] + CMP + H(+)

Left to rightBalance undeterminableRhea 36551

eicosanoyl-CoA + sphinganine = N-eicosanoylsphinganine + CoA + H(+)

Left to rightBalancedRhea 36555

cis-4-hydroxy-D-proline + A = 4-hydroxy-1-pyrroline-2-carboxylate + AH2 + H(+)

Direction not assertedBalancedRhea 36559

GDP-beta-L-colitose + NADP(+) = GDP-4-dehydro-3,6-dideoxy-alpha-D-mannose + NADPH + H(+)

Direction not assertedBalancedRhea 36563

GDP-beta-L-colitose + NAD(+) = GDP-4-dehydro-3,6-dideoxy-alpha-D-mannose + NADH + H(+)

Direction not assertedBalancedRhea 36567

sphinganine + tetradecanoyl-CoA = N-(tetradecanoyl)-sphinganine + CoA + H(+)

Left to rightBalancedRhea 36571

sphinganine + (9Z)-octadecenoyl-CoA = N-(9Z-octadecenoyl)-sphinganine + CoA + H(+)

Left to rightBalancedRhea 36575

dTDP-alpha-D-fucose + NAD(+) = dTDP-4-dehydro-6-deoxy-alpha-D-glucose + NADH + H(+)

Direction not assertedBalancedRhea 36579

dTDP-alpha-D-fucose + NADP(+) = dTDP-4-dehydro-6-deoxy-alpha-D-glucose + NADPH + H(+)

Direction not assertedBalancedRhea 36583

an aldopyranose + NADP(+) = aldono-1,5-lactone + NADPH + H(+)

Direction not assertedBalance undeterminableRhea 36587

(S)-2-chloropropanoate + NADP(+) = 2-chloroacrylate + NADPH + H(+)

Direction not assertedBalancedRhea 36591

hydrogen sulfide + NADP(+) = sulfur + NADPH

Direction not assertedBalancedRhea 36595

hydrogen sulfide + NAD(+) = sulfur + NADH

Direction not assertedBalancedRhea 36599

L-enduracididine + 2-oxoglutarate + O2 = (3S)-3-hydroxy-L-enduracididine + succinate + CO2

Direction not assertedBalancedRhea 36603

L-arginine + 2-oxoglutarate + O2 = (2S,3S)-hydroxyarginine + succinate + CO2

Direction not assertedBalancedRhea 36607

(3S,5S)-carbapenam-3-caboxylate + 2-oxoglutarate + O2 = (5R)-carbapen-2-em-3-carboxylate + succinate + CO2 + H2O

Direction not assertedBalancedRhea 36611

2-hydroxyoctadecanoyl-CoA + sphinganine = N-(2-hydroxyoctadecanoyl)-sphinganine + CoA + H(+)

Left to rightBalancedRhea 36615

2-hydroxydocosanoyl-CoA + sphinganine = N-(2-hydroxydocosanoyl)-sphinganine + CoA + H(+)

Left to rightBalancedRhea 36619

3-phenylpyruvate + S-adenosyl-L-methionine = (3S)-2-oxo-3-phenylbutanoate + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 36623

2-hydroxytetracosanoyl-CoA + sphinganine = N-(2-hydroxytetracosanoyl)-sphinganine + CoA + H(+)

Left to rightBalancedRhea 36627

D-ribulose 1,5-bisphosphate + O2 = 2-phosphoglycolate + (2R)-3-phosphoglycerate + 2 H(+)

Direction not assertedBalancedRhea 36631

4-demethyl-7-[(3S)-3-amino-3-carboxypropyl]wyosine(37) in tRNA(Phe) + S-adenosyl-L-methionine = 7-[(3S)-3-amino-3-carboxypropyl]wyosine(37) in tRNA(Phe) + S-adenosyl-L-homocysteine + H(+)

Left to rightBalance undeterminableRhea 36635

3-O-phospho-alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-[alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-Man-(1->2)-alpha-D-Man-(1->2)](n)-alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-GlcNAc-di-trans,octa-cis-undecaprenyl diphosphate + S-adenosyl-L-methionine = 3-O-methylphospho-alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-[alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-Man-(1->2)-alpha-D-Man-(1->2)](n)-alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-GlcNAc-di-trans,octa-cis-undecaprenyl diphosphate + S-adenosyl-L-homocysteine

Direction not assertedBalance undeterminableRhea 36639

emodin + S-adenosyl-L-methionine = questin + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 36643

2-hydroxyhexadecanoyl-CoA + sphinganine = N-(2-hydroxyhexadecanoyl)-sphinganine + CoA + H(+)

Left to rightBalancedRhea 36647

8-desmethylnovobiocic acid + S-adenosyl-L-methionine = novobiocic acid + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 36651

desmethyldescarbamoylnovobiocin + S-adenosyl-L-methionine = descarbamoylnovobiocin + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 36655

descarbamoylnovobiocin + carbamoyl phosphate = novobiocin + phosphate

Direction not assertedBalancedRhea 36659

(S)-1-pyrroline-5-carboxylate + malonyl-CoA + H2O + H(+) = (2S,5S)-5-carboxymethylproline + CO2 + CoA

Direction not assertedBalancedRhea 36663

(15Z)-tetracosenoyl-CoA + sphinganine = N-(15Z-tetracosenoyl)-sphinganine + CoA + H(+)

Left to rightBalancedRhea 36667

(17Z)-hexacosenoyl-CoA + sphinganine = N-[(17Z)-hexacosenoyl]dihydrosphingosine + CoA + H(+)

Direction not assertedBalancedRhea 36671

octacosanoyl-CoA + sphinganine = N-(octacosanoyl)-sphinganine + CoA + H(+)

Left to rightBalancedRhea 36675

dTDP-6-deoxy-alpha-D-allose + NAD(+) = dTDP-4-dehydro-6-deoxy-alpha-D-allose + NADH + H(+)

Direction not assertedBalancedRhea 36679

L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA

Left to rightBalance undeterminableRhea 36683

sphing-4-enine + hexadecanoyl-CoA = N-hexadecanoylsphing-4-enine + CoA + H(+)

Left to rightBalancedRhea 36687

sphing-4-enine + octadecanoyl-CoA = N-octadecanoylsphing-4-enine + CoA + H(+)

Left to rightBalancedRhea 36691

dTDP-4-O-demethyl-beta-L-noviose + novobiocic acid = desmethyldescarbamoylnovobiocin + dTDP + H(+)

Direction not assertedBalancedRhea 36695

3-amino-4,7-dihydroxycoumarin + 3-dimethylallyl-4-hydroxybenzoate + ATP = 8-desmethylnovobiocic acid + AMP + diphosphate

Direction not assertedBalancedRhea 36699

(2S,5S)-5-carboxymethylproline + ATP = (3S,5S)-carbapenam-3-caboxylate + AMP + diphosphate + H(+)

Direction not assertedBalancedRhea 36703

Page 124 of 372