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CompoundsSubstances with curated findings
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ReactionsRhea and Human-GEM, by subsystem
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Reference

Evidence

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Reach

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

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Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSourceClear

Reactions

6,101–6,150 of 18,558 reactions from Rhea

(E)-caffeoyl-CoA + H2O = 3,4-dihydroxybenzaldehyde + acetyl-CoA
Direction not assertedBalancedRhea 36307
3,4-dihydroxybenzaldehyde + NAD(+) + H2O = 3,4-dihydroxybenzoate + NADH + 2 H(+)
Direction not assertedBalancedRhea 36311
hexadecanoyl-CoA + 2 NADPH + 2 H(+) = hexadecan-1-ol + 2 NADP(+) + CoA
Left to rightBalancedRhea 36315
octadecanoyl-CoA + 2 NADPH + 2 H(+) = octadecan-1-ol + 2 NADP(+) + CoA
Left to rightBalancedRhea 36319
(9Z)-octadecenoyl-CoA + 2 NADPH + 2 H(+) = (9Z)-octadecen-1-ol + 2 NADP(+) + CoA
Left to rightBalancedRhea 36323
dimethylallyl diphosphate + ADP = N(6)-(dimethylallyl)adenosine 5'-diphosphate + diphosphate
Direction not assertedBalancedRhea 36327
dimethylallyl diphosphate + ATP = N(6)-(dimethylallyl)adenosine 5'-triphosphate + diphosphate

Direction not assertedBalancedRhea 36331

D-glucuronate + NAD(+) + H2O = D-glucarate + NADH + 2 H(+)

Direction not assertedBalancedRhea 36335

N(6)-dimethylallyladenosine(37) in tRNA + (sulfur carrier)-SH + AH2 + S-adenosyl-L-methionine = 2-thio-N(6)-dimethylallyladenosine(37) in tRNA + (sulfur carrier)-H + 5'-deoxyadenosine + L-methionine + A + H(+)

Direction not assertedBalancedRhea 36339

2-methylsulfanyl-N(6)-(Delta(2)-isopentenyl)adenosine in tRNA + NADPH + O2 + H(+) = 2-methylsulfanyl-N(6)-(cis-4-hydroxy-Delta(2)-isopentenyl)adenosine in tRNA + NADP(+) + H2O

Direction not assertedBalancedRhea 36343

N(1)-methylguanosine(37) in tRNA(Phe) + pyruvate + S-adenosyl-L-methionine = 4-demethylwyosine(37) in tRNA(Phe) + 5'-deoxyadenosine + L-methionine + CO2 + H2O

Left to rightBalancedRhea 36347

L-aspartate(89)-[ribosomal protein uS12]-methanesulfate + AH2 + S-adenosyl-L-methionine = 3-methylsulfanyl-L-aspartate(89)-[ribosomal protein uS12]-hydrogen + 5'-deoxyadenosine + L-methionine + A + H(+)

Direction not assertedBalance undeterminableRhea 36351

4-demethylwyosine(37) in tRNA(Phe) + S-adenosyl-L-methionine = 4-demethyl-7-[(3S)-3-amino-3-carboxypropyl]wyosine(37) in tRNA(Phe) + S-methyl-5'-thioadenosine + H(+)

Direction not assertedBalance undeterminableRhea 36355

2 a plastoquinone + 4 hnu + 2 H2O = 2 a plastoquinol + O2

Direction not assertedBalance undeterminableRhea 36359

(9Z,12Z)-octadecadienoyl-CoA + 2 NADPH + 2 H(+) = (9Z,12Z)-octadecadien-1-ol + 2 NADP(+) + CoA

Left to rightBalancedRhea 36363

(S)-alpha-hydroxyglutarate-gamma-lactone + H2O = 2-hydroxyglutarate + H(+)

Direction not assertedBalancedRhea 36367

(2S)-hydroxybutanoate + NAD(+) = 2-oxobutanoate + NADH + H(+)

Direction not assertedBalancedRhea 36371

carbamoyl phosphate + ATP + H2O = carbamoyl adenylate + phosphate + diphosphate

Direction not assertedBalancedRhea 36375

3-dehydro-4alpha-methylzymosterol + NADPH + H(+) = 4alpha-methylzymosterol + NADP(+)

Left to rightBalancedRhea 36379

tobramycin + carbamoyl adenylate = nebramycin 5' + AMP + H(+)

Direction not assertedBalancedRhea 36383

carbamoyl adenylate + kanamycin A = 6''-O-carbamoylkanamycin A + AMP + H(+)

Direction not assertedBalancedRhea 36387

cholesterol + NADP(+) = desmosterol + NADPH + H(+)

Right to leftBalancedRhea 36391

7-dehydrocholesterol + NADP(+) = 7-dehydrodesmosterol + NADPH + H(+)

Direction not assertedBalancedRhea 36395

5alpha-cholest-8-en-3beta-ol + NADP(+) = zymosterol + NADPH + H(+)

Right to leftBalancedRhea 36399

a cholesterol ester + H2O = cholesterol + a fatty acid + H(+)

Left to rightBalance undeterminableRhea 36403

L-threonine + hydrogencarbonate + ATP = L-threonylcarbamoyladenylate + diphosphate + H2O

Direction not assertedBalancedRhea 36407

7-dehydrocholesterol + hnu = calciol

Direction not assertedBalance undeterminableRhea 36411

2-[(3S)-amino-3-carboxypropyl]-L-histidyl-[translation elongation factor 2] + 3 S-adenosyl-L-methionine = diphthine-[translation elongation factor 2] + 3 S-adenosyl-L-homocysteine + 3 H(+)

Direction not assertedBalance undeterminableRhea 36415

2-[(3S)-amino-3-carboxypropyl]-L-histidyl-[translation elongation factor 2] + S-adenosyl-L-methionine = 2-[(3S)-3-carboxy-3-(methylamino)propyl]-L-histidyl-[translation elongation factor 2] + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalance undeterminableRhea 36419

2-[(3S)-3-carboxy-3-(methylamino)propyl]-L-histidyl-[translation elongation factor 2] + S-adenosyl-L-methionine = 2-[(3S)-3-carboxy-3-(dimethylamino)propyl]-L-histidyl-[translation elongation factor 2] + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalance undeterminableRhea 36423

2-[(3S)-3-carboxy-3-(dimethylamino)propyl]-L-histidyl-[translation elongation factor 2] + S-adenosyl-L-methionine = diphthine-[translation elongation factor 2] + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalance undeterminableRhea 36427

a purine 2'-deoxy-D-ribonucleoside + phosphate = a purine nucleobase + 2-deoxy-alpha-D-ribose 1-phosphate

Direction not assertedBalance undeterminableRhea 36431

a 1,2-diacyl-sn-glycero-3-phosphate(in) = a 1,2-diacyl-sn-glycero-3-phosphate(out)

Left to rightBalance undeterminableTransportRhea 36435

a 1,2-diacyl-sn-glycero-3-phosphoethanolamine(in) + ATP + H2O = a 1,2-diacyl-sn-glycero-3-phosphoethanolamine(out) + ADP + phosphate + H(+)

Left to rightBalance undeterminableTransportRhea 36439

dihydrochanoclavine-I aldehyde = 6,8-dimethyl-6,7-didehydroergoline + H2O

Direction not assertedBalancedRhea 36443

glycyl-L-proline(out) + ATP + H2O = glycyl-L-proline(in) + ADP + phosphate + H(+)

Direction not assertedBalancedTransportRhea 36447

glycyl-L-glutamate(out) + ATP + H2O = glycyl-L-glutamate(in) + ADP + phosphate + H(+)

Direction not assertedBalancedTransportRhea 36451

L-alanylglycine(out) + ATP + H2O = L-alanylglycine(in) + ADP + phosphate + H(+)

Direction not assertedBalancedTransportRhea 36455

glycyl-L-proline + H2O = L-proline + glycine

Direction not assertedBalancedRhea 36459

glycyl-L-glutamate + H2O = glycine + L-glutamate

Direction not assertedBalancedRhea 36463

L-alanylglycine + H2O = L-alanine + glycine

Direction not assertedBalancedRhea 36467

3,4,5-trihydroxybenzoate(out) + H(+)(out) = 3,4,5-trihydroxybenzoate(in) + H(+)(in)

Direction not assertedBalancedTransportRhea 36471

(5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + malonyl-CoA + H(+) = (7Z,10Z,13Z,16Z)-3-oxodocosatetraenoyl-CoA + CO2 + CoA

Left to rightBalancedRhea 36475

(7Z,10Z,13Z,16Z)-docosatetraenoyl-CoA + malonyl-CoA + H(+) = (9Z,12Z,15Z,18Z)-3-oxotetracosatetraenoyl-CoA + CO2 + CoA

Left to rightBalancedRhea 36479

(5Z,8Z,11Z,14Z,17Z)-eicosapentaenoyl-CoA + malonyl-CoA + H(+) = 3-oxo-(7Z,10Z,13Z,16Z,19Z)-docosapentaenoyl-CoA + CO2 + CoA

Left to rightBalancedRhea 36483

S-adenosyl 3-(methylsulfanyl)propylamine + agmatine = N(1)-(3-aminopropyl)agmatine + S-methyl-5'-thioadenosine + H(+)

Direction not assertedBalancedRhea 36487

(7Z,10Z,13Z,16Z,19Z)-docosapentaenoyl-CoA + malonyl-CoA + H(+) = (9Z,12Z,15Z,18Z,21Z)-3-oxotetracosapentaenoyl-CoA + CO2 + CoA

Left to rightBalancedRhea 36491

alpha-D-glucose + ATP = alpha-D-glucose 6-phosphate + ADP + H(+)

Direction not assertedBalancedRhea 36495

2-dehydro-3-deoxy-L-rhamnonate + NAD(+) = 2,4-didehydro-3-deoxy-L-rhamnonate + NADH + H(+)

Direction not assertedBalancedRhea 36499

(9Z,12Z)-octadecadienoyl-CoA + malonyl-CoA + H(+) = (11Z,14Z)-3-oxoicosa-11,14-dienoyl-CoA + CO2 + CoA

Left to rightBalancedRhea 36503

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