Skip to content

Reference

Evidence

CompoundsSubstances with curated findings
OutcomesMeasured endpoints
ProteinsTransporters and enzymes
InteractionsPairs that share biology
PapersEvery paper a finding cites
ArticlesReadings of the evidence

Chemistry

ReactionsRhea and Human-GEM, by subsystem
ReachWhat a compound can become

Reference layer

PathwaysReactions grouped under one name
ProcessesWhat proteins are annotated as doing
AnatomyTissues, by what is expressed there
Cell typesCells, by what is expressed there
OrganismsSpecies a compound is prepared from
MaterialsSubstances that are not one molecule
AssessmentsRegulatory determinations, transcribed
DiseasesFeatures, genes, and where each sits

Atlas Graph Twin Access

Search the graph

Reference

Evidence

Compounds
Outcomes
Proteins
Interactions
Papers
Articles

Chemistry

Reactions
Reach

Reference layer

Pathways
Processes
Anatomy
Cell types
Organisms
Materials
Assessments
Diseases

Atlas Graph Twin Access

Loading the page.

Catalyst

Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

The graph

Compounds
Outcomes
Proteins
Atlas
Interactions
Papers
Articles
Graph
Search

Reference layer

Pathways
Processes
Anatomy
Cell types
Organisms
Materials
Assessments
Diseases
Reactions
Reach

How it works

Mission
Method
Twin
How to read the evidence
Sources and licences

Build on it

Access
In your assistant
For agents
Query the graph
Bulk export

A reference for what the literature reports. Not medical advice.

© 2026 CatalystPrivacy TermsReference data under the licences listed on the attribution page.

Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSourceClear

Reactions

6,051–6,100 of 18,558 reactions from Rhea

gibberellin A4 + S-adenosyl-L-methionine = O-methyl gibberellin A4 + S-adenosyl-L-homocysteine
Direction not assertedBalancedRhea 36107
gibberellin A1 + S-adenosyl-L-methionine = O-methyl gibberellin A1 + S-adenosyl-L-homocysteine
Direction not assertedBalancedRhea 36111
gibberellin A3 + S-adenosyl-L-methionine = O-methyl gibberellin A3 + S-adenosyl-L-homocysteine
Direction not assertedBalancedRhea 36115
gibberellin A9 + S-adenosyl-L-methionine = O-methyl gibberellin A9 + S-adenosyl-L-homocysteine
Direction not assertedBalancedRhea 36119
gibberellin A20 + S-adenosyl-L-methionine = gibberellin A20 methyl ester + S-adenosyl-L-homocysteine
Direction not assertedBalancedRhea 36123
gibberellin A34 + S-adenosyl-L-methionine = O-methyl gibberellin A34 + S-adenosyl-L-homocysteine
Direction not assertedBalancedRhea 36127

(indol-3-yl)acetate + S-adenosyl-L-methionine = methyl (indol-3-yl)acetate + S-adenosyl-L-homocysteine

Direction not assertedBalancedRhea 36131

(2E)-hexadecenal + NAD(+) + H2O = (E)-hexadec-2-enoate + NADH + 2 H(+)

Left to rightBalancedRhea 36135

(E)-hexadec-2-enoate + ATP + CoA = (2E)-hexadecenoyl-CoA + AMP + diphosphate

Left to rightBalancedRhea 36139

(2E)-hexadecenoyl-CoA + NADPH + H(+) = hexadecanoyl-CoA + NADP(+)

Left to rightBalancedRhea 36143

benzyl alcohol + acetyl-CoA = benzyl acetate + CoA

Direction not assertedBalancedRhea 36147

(E)-cinnamyl alcohol + acetyl-CoA = (E)-cinnamyl acetate + CoA

Direction not assertedBalancedRhea 36151

Co(II)-factor III + AH2 + S-adenosyl-L-methionine = Co-precorrin-4 + A + S-adenosyl-L-homocysteine

Direction not assertedBalancedRhea 36155

2,3-bis-O-(phytanyl)-sn-glycerol 1-phosphate + 8 oxidized 2[4Fe-4S]-[ferredoxin] = 2,3-bis-O-(geranylgeranyl)-sn-glycerol 1-phosphate + 8 reduced 2[4Fe-4S]-[ferredoxin] + 16 H(+)

Direction not assertedBalance undeterminableRhea 36159

5-phospho-alpha-D-ribose 1-diphosphate + nicotinate + ATP + H2O = nicotinate beta-D-ribonucleotide + ADP + phosphate + diphosphate

Direction not assertedBalancedRhea 36163

a 2'-deoxyribonucleoside 5'-phosphate + H2O = a 2'-deoxyribonucleoside + phosphate

Direction not assertedBalance undeterminableRhea 36167

a long chain fatty alcohol + a 1-acylglycerone 3-phosphate = a 1-O-alkylglycerone 3-phosphate + a long-chain fatty acid + H(+)

Left to rightBalance undeterminableRhea 36171

a 1-O-alkylglycerone 3-phosphate + NADPH + H(+) = a 1-O-alkyl-sn-glycero-3-phosphate + NADP(+)

Direction not assertedBalance undeterminableRhea 36175

1-O-alkyl-2-acyl-sn-glycerol + CDP-choline = a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine + CMP + H(+)

Left to rightBalance undeterminableRhea 36179

a 1-O-alkyl-2-acetyl-sn-glycerol + CDP-choline = a 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine + CMP + H(+)

Direction not assertedBalance undeterminableRhea 36183

1-O-alkyl-2-acyl-sn-glycerol + CDP-ethanolamine = a 1-O-alkyl-2-acyl-sn-glycero-3-phosphoethanolamine + CMP + H(+)

Left to rightBalance undeterminableRhea 36187

a 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphoethanolamine + choline = a 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphocholine + ethanolamine

Direction not assertedBalance undeterminableRhea 36191

a 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphoethanolamine + H2O = a 1-O-(1Z-alkenyl)-sn-glycero-3-phosphoethanolamine + a carboxylate + H(+)

Direction not assertedBalance undeterminableRhea 36195

a 1-O-(1Z-alkenyl)-sn-glycero-3-phosphoethanolamine + H2O = 1-O-(1Z-alkenyl)-sn-glycerol + phosphoethanolamine + H(+)

Direction not assertedBalance undeterminableRhea 36199

a 1-O-(1Z-alkenyl)-sn-glycero-3-phosphoethanolamine + H2O = a 1-O-(1Z-alkenyl)-sn-glycero-3-phosphate + ethanolamine + H(+)

Direction not assertedBalance undeterminableRhea 36203

a 1-O-(1Z-alkenyl)-sn-glycero-3-phosphate + an acyl-CoA = 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphate + CoA

Direction not assertedBalance undeterminableRhea 36207

1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphate + H2O = a 1-O-(1Z-alkenyl)-2-acyl-sn-glycerol + phosphate

Direction not assertedBalance undeterminableRhea 36211

a 1-O-(1Z-alkenyl)-2-acyl-sn-glycerol + CDP-ethanolamine = a 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphoethanolamine + CMP + H(+)

Direction not assertedBalance undeterminableRhea 36215

a 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphoethanolamine + H2O = 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphate + ethanolamine + H(+)

Direction not assertedBalance undeterminableRhea 36219

a 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphoethanolamine + H2O = a 1-O-(1Z-alkenyl)-2-acyl-sn-glycerol + phosphoethanolamine + H(+)

Direction not assertedBalance undeterminableRhea 36223

a 1-O-(1Z-alkenyl)-2-acyl-sn-glycerol + CDP-choline = a 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphocholine + CMP + H(+)

Left to rightBalance undeterminableRhea 36227

a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine + H2O = a 1-O-alkyl-sn-glycero-3-phosphocholine + a fatty acid + H(+)

Left to rightBalance undeterminableRhea 36231

a 1-O-alkyl-sn-glycero-3-phosphate + an acyl-CoA = 1-O-alkyl-2-acyl-sn-glycero-3-phosphate + CoA

Direction not assertedBalance undeterminableRhea 36235

1-O-alkyl-2-acyl-sn-glycero-3-phosphate + H2O = 1-O-alkyl-2-acyl-sn-glycerol + phosphate

Direction not assertedBalance undeterminableRhea 36239

(E)-anol + acetate + NADP(+) = (E)-coumaryl acetate + NADPH

Direction not assertedBalancedRhea 36243

(E)-anol + S-adenosyl-L-methionine = (E)-anethole + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 36247

(E)-ferulate + ATP + CoA = (E)-feruloyl-CoA + AMP + diphosphate

Direction not assertedBalancedRhea 36251

1-O-(1,2-saturated-alkyl)-sn-glycerol + (6R)-L-erythro-5,6,7,8-tetrahydrobiopterin + O2 = a 1-(1-hydroxyalkyl)-sn-glycerol + (6R)-L-erythro-6,7-dihydrobiopterin + H2O

Direction not assertedBalance undeterminableRhea 36255

a 1-(1-hydroxyalkyl)-sn-glycerol = an aldehyde + glycerol

Direction not assertedBalance undeterminableRhea 36259

hydroxyurea + O-acetyl-L-serine = O-ureido-L-serine + acetate + H(+)

Direction not assertedBalancedRhea 36263

caffeine + NADH + O2 + H(+) = theobromine + formaldehyde + NAD(+) + H2O

Direction not assertedBalancedRhea 36267

caffeine + NADPH + O2 + H(+) = theobromine + formaldehyde + NADP(+) + H2O

Direction not assertedBalancedRhea 36271

theophylline + NADPH + O2 + H(+) = 3-methylxanthine + formaldehyde + NADP(+) + H2O

Direction not assertedBalancedRhea 36275

theophylline + NADH + O2 + H(+) = 3-methylxanthine + formaldehyde + NAD(+) + H2O

Direction not assertedBalancedRhea 36279

1,7-dimethylxanthine + NADPH + O2 + H(+) = 7-methylxanthine + formaldehyde + NADP(+) + H2O

Direction not assertedBalancedRhea 36283

theobromine + NADPH + O2 + H(+) = 7-methylxanthine + formaldehyde + NADP(+) + H2O

Direction not assertedBalancedRhea 36287

3-methylxanthine + NADPH + O2 + H(+) = xanthine + formaldehyde + NADP(+) + H2O

Direction not assertedBalancedRhea 36291

alpha-maltose 6'-phosphate + H2O = D-maltose + phosphate

Direction not assertedBalancedRhea 36295

(E)-caffeate + ATP + CoA = (E)-caffeoyl-CoA + AMP + diphosphate

Direction not assertedBalancedRhea 36299

a fatty acyl-CoA + 2 NADPH + 2 H(+) = a long-chain primary fatty alcohol + 2 NADP(+) + CoA

Direction not assertedBalance undeterminableRhea 36303

Page 122 of 372