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Reference

Evidence

CompoundsSubstances with curated findings
OutcomesMeasured endpoints
ProteinsTransporters and enzymes
InteractionsPairs that share biology
PapersEvery paper a finding cites
ArticlesReadings of the evidence

Chemistry

ReactionsRhea and Human-GEM, by subsystem
ReachWhat a compound can become

Reference layer

PathwaysReactions grouped under one name
ProcessesWhat proteins are annotated as doing
AnatomyTissues, by what is expressed there
Cell typesCells, by what is expressed there
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MaterialsSubstances that are not one molecule
AssessmentsRegulatory determinations, transcribed
DiseasesFeatures, genes, and where each sits

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Reference

Evidence

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Outcomes
Proteins
Interactions
Papers
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Chemistry

Reactions
Reach

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Anatomy
Cell types
Organisms
Materials
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Diseases

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

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Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSourceClear

Reactions

551–600 of 18,558 reactions from Rhea

a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + H2O = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + phosphate
Left to rightBalance undeterminableRhea 12316
17-O-acetylnorajmaline + NADP(+) = (2R)-1,2-dihydrovomilenine + NADPH + 2 H(+)
Direction not assertedBalancedRhea 12320
N(4)-(beta-N-acetyl-D-glucosaminyl)-L-asparagine + H2O = N-acetyl-D-glucosamine + L-asparagine
Direction not assertedBalancedRhea 12324
[(1->3)-alpha-D-glucosyl](n) + phosphate = [(1->3)-alpha-D-glucosyl](n-1) + beta-D-glucose 1-phosphate
Direction not assertedBalance undeterminableRhea 12328
Fe(3+)(out) + ATP + H2O = Fe(3+)(in) + ADP + phosphate + H(+)
Direction not assertedBalancedTransportRhea 12332
carboxymethoxysuccinate = glycolate + fumarate
Direction not assertedBalancedRhea 12336

N-terminal L-lysyl-[protein] + L-leucyl-tRNA(Leu) = N-terminal L-leucyl-L-lysyl-[protein] + tRNA(Leu) + H(+)

Direction not assertedBalance undeterminableRhea 12340

(S)-4-amino-5-oxopentanoate + tRNA(Glu) + NADP(+) = L-glutamyl-tRNA(Glu) + NADPH + H(+)

Direction not assertedBalancedRhea 12344

(S)-muconolactone = (4,5-dihydro-5-oxofuran-2-yl)-acetate

Direction not assertedBalancedRhea 12348

L-gulono-1,4-lactone + O2 = L-xylo-hex-3-ulonolactone + H2O2

Direction not assertedBalancedRhea 12352

D-mannose 6-phosphate = D-fructose 6-phosphate

Direction not assertedBalancedRhea 12356

13-hydroxylupanine + (2E)-2-methylbut-2-enoyl-CoA = 13-(2-methylcrotonoyloxy)lupanine + CoA

Direction not assertedBalancedRhea 12360

1-(beta-D-ribofuranosyl)-1,4-dihydronicotinamide + a quinone + H(+) = beta-nicotinamide D-riboside + a quinol

Direction not assertedBalance undeterminableRhea 12364

2-dehydro-D-gluconate + A = 2,5-didehydro-D-gluconate + AH2

Direction not assertedBalancedRhea 12368

2-(5-oxo-2,5-dihydrofuran-2-ylidene)acetate + H2O = 4-oxohex-2-enedioate + H(+)

Direction not assertedBalancedRhea 12372

L-fuculose + ATP = L-fuculose 1-phosphate + ADP + H(+)

Direction not assertedBalancedRhea 12376

L-2,4-diaminobutanoate + pyruvate = L-aspartate 4-semialdehyde + L-alanine

Direction not assertedBalancedRhea 12380

5,6-dihydrouracil + O2 = uracil + H2O2

Direction not assertedBalancedRhea 12384

formononetin + reduced [NADPH--hemoprotein reductase] + O2 = 2'-hydroxyformononetin + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 12388

dTDP-D-galactose + 2 NADP(+) + H2O = dTDP-D-galacturonate + 2 NADPH + 3 H(+)

Direction not assertedBalancedRhea 12396

beta-nicotinamide D-ribonucleotide + H2O = nicotinate beta-D-ribonucleotide + NH4(+)

Direction not assertedBalancedRhea 12400

D-glucose + UDP-alpha-D-galactose = lactose + UDP + H(+)

Left to rightBalancedRhea 12404

L-lysine + NAD(+) = L-1-piperideine-6-carboxylate + NH4(+) + NADH + 2 H(+)

Direction not assertedBalancedRhea 12408

(2R)-3-phosphoglycerate + H2O = (R)-glycerate + phosphate

Direction not assertedBalancedRhea 12412

beta-alanyl-CoA = acryloyl-CoA + NH4(+)

Direction not assertedBalancedRhea 12416

D-tagatofuranose 6-phosphate + ATP = D-tagatofuranose 1,6-bisphosphate + ADP + H(+)

Direction not assertedBalancedRhea 12420

(3S)-3-hydroxy-L-aspartate = oxaloacetate + NH4(+)

Direction not assertedBalancedRhea 12424

2-hydroxy-1,4-benzoquinone + NADH + 2 H(+) = benzene-1,2,4-triol + NAD(+)

Direction not assertedBalancedRhea 12428

UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-gamma-D-glutamyl-L-lysyl-D-alanyl-D-alanine + L-alanyl-tRNA(Ala) = UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-gamma-D-glutamyl-N(6)-(L-alanyl)-L-lysyl-D-alanyl-D-alanine + tRNA(Ala) + H(+)

Direction not assertedBalancedRhea 12432

(E)-caffeoyl-CoA + putrescine = N-caffeoylputrescine + CoA + H(+)

Direction not assertedBalancedRhea 12436

L-saccharopine + NAD(+) + H2O = L-lysine + 2-oxoglutarate + NADH + H(+)

Direction not assertedBalancedRhea 12440

hexadecanal + NADP(+) = (2E)-hexadecenal + NADPH + H(+)

Direction not assertedBalancedRhea 12444

(R)-pantothenate + H2O = (R)-pantoate + beta-alanine

Direction not assertedBalancedRhea 12448

1D-myo-inositol 3,4,5,6-tetrakisphosphate + ATP = 1D-myo-inositol 1,3,4,5,6-pentakisphosphate + ADP + H(+)

ReversibleBalancedRhea 12452

D-ribitol 5-phosphate + CTP + H(+) = CDP-L-ribitol + diphosphate

Direction not assertedBalancedRhea 12456

(S)-malate = fumarate + H2O

ReversibleBalancedRhea 12460

myo-inositol + UDP-alpha-D-galactose = alpha-D-galactosyl-(1->3)-1D-myo-inositol + UDP + H(+)

Direction not assertedBalancedRhea 12464

avenacoside A + H2O = 26-desgluco-avenacoside A + D-glucose

Direction not assertedBalancedRhea 12468

N-ethylglycine + O2 + H2O = ethylamine + glyoxylate + H2O2

Direction not assertedBalancedRhea 12472

N-formyl-L-glutamate + H2O = formate + L-glutamate

Direction not assertedBalancedRhea 12476

5-aminolevulinate + pyruvate = 4,5-dioxopentanoate + L-alanine

Direction not assertedBalancedRhea 12480

a ribonucleoside 5'-phosphate + H2O = a ribonucleoside + phosphate

Left to rightBalance undeterminableRhea 12484

2-amino-2-deoxy-D-gluconate = 2-dehydro-3-deoxy-D-gluconate + NH4(+)

Direction not assertedBalancedRhea 12488

L-methionine = D-methionine

Direction not assertedBalancedRhea 12492

2 Fe(2+) + O2 + 4 H2O = 2 iron(III) oxide-hydroxide + H2O2 + 6 H(+)

Direction not assertedBalancedRhea 12496

(3R)-1,4-thiomorpholine-3-carboxylate + NADP(+) = 3,4-dehydrothiomorpholine-3-carboxylate + NADPH + 2 H(+)

Right to leftBalancedRhea 12500

(3R)-1,4-thiomorpholine-3-carboxylate + NAD(+) = 3,4-dehydrothiomorpholine-3-carboxylate + NADH + 2 H(+)

Right to leftBalancedRhea 12504

loganate + S-adenosyl-L-methionine = loganin + S-adenosyl-L-homocysteine

Direction not assertedBalancedRhea 12508

D-aspartate + O2 + H2O = oxaloacetate + H2O2 + NH4(+)

Left to rightBalancedRhea 12512

(2E,6E)-farnesyl diphosphate = (+)-(R)-germacrene A + diphosphate

Direction not assertedBalancedRhea 12516

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