Skip to content

Reference

Evidence

CompoundsSubstances with curated findings
OutcomesMeasured endpoints
ProteinsTransporters and enzymes
InteractionsPairs that share biology
PapersEvery paper a finding cites
ArticlesReadings of the evidence

Chemistry

ReactionsRhea and Human-GEM, by subsystem
ReachWhat a compound can become

Reference layer

PathwaysReactions grouped under one name
ProcessesWhat proteins are annotated as doing
AnatomyTissues, by what is expressed there
Cell typesCells, by what is expressed there
OrganismsSpecies a compound is prepared from
MaterialsSubstances that are not one molecule
AssessmentsRegulatory determinations, transcribed
DiseasesFeatures, genes, and where each sits

Atlas Graph Twin Access

Search the graph

Reference

Evidence

Compounds
Outcomes
Proteins
Interactions
Papers
Articles

Chemistry

Reactions
Reach

Reference layer

Pathways
Processes
Anatomy
Cell types
Organisms
Materials
Assessments
Diseases

Atlas Graph Twin Access

Loading the page.

Catalyst

Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

The graph

Compounds
Outcomes
Proteins
Atlas
Interactions
Papers
Articles
Graph
Search

Reference layer

Pathways
Processes
Anatomy
Cell types
Organisms
Materials
Assessments
Diseases
Reactions
Reach

How it works

Mission
Method
Twin
How to read the evidence
Sources and licences

Build on it

Access
In your assistant
For agents
Query the graph
Bulk export

A reference for what the literature reports. Not medical advice.

© 2026 CatalystPrivacy TermsReference data under the licences listed on the attribution page.

Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSourceClear

Reactions

5,901–5,950 of 18,558 reactions from Rhea

(2S)-naringenin + reduced [NADPH--hemoprotein reductase] + O2 = 2-hydroxy-2,3-dihydrogenistein + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)
Direction not assertedBalance undeterminableRhea 35487
N-(4-aminobenzoyl)-L-glutamate + H2O = 4-aminobenzoate + L-glutamate
Direction not assertedBalancedRhea 35495
11-oxo-beta-amyrin + 3 reduced [NADPH--hemoprotein reductase] + 3 O2 = glycyrrhetinate + 3 oxidized [NADPH--hemoprotein reductase] + 4 H2O + 4 H(+)
Direction not assertedBalance undeterminableRhea 35499
11-oxo-beta-amyrin + reduced [NADPH--hemoprotein reductase] + O2 = 30-hydroxy-11-oxo-beta-amyrin + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)
Direction not assertedBalance undeterminableRhea 35503
30-hydroxy-11-oxo-beta-amyrin + reduced [NADPH--hemoprotein reductase] + O2 = glycyrrhetaldehyde + oxidized [NADPH--hemoprotein reductase] + 2 H2O + H(+)
Direction not assertedBalance undeterminableRhea 35507
glycyrrhetaldehyde + reduced [NADPH--hemoprotein reductase] + O2 = glycyrrhetinate + oxidized [NADPH--hemoprotein reductase] + H2O + 2 H(+)

Direction not assertedBalance undeterminableRhea 35511

4'''-demalonylsalvianin + malonyl-CoA = salvianin + CoA

Direction not assertedBalancedRhea 35515

(5Z,8Z,11Z,14Z,17Z-eicosapentaenoyl) ethanolamine + H2O = (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate + ethanolamine

Direction not assertedBalancedRhea 35519

N-ethylmaleimide + NADPH + H(+) = N-ethylsuccinimide + NADP(+)

Direction not assertedBalancedRhea 35523

N-ethylmaleimide + NADH + H(+) = N-ethylsuccinimide + NAD(+)

Direction not assertedBalancedRhea 35527

cyclo(L-phenylalanyl-L-leucyl) + 2 O2 = albonoursin + 2 H2O2

Direction not assertedBalancedRhea 35531

cyclo(L-phenylalanyl-L-leucyl) + O2 = cyclo[(Z)-alpha,beta-didehydrophenylalanyl-L-leucyl] + H2O2

Direction not assertedBalancedRhea 35535

cyclo[(Z)-alpha,beta-didehydrophenylalanyl-L-leucyl] + O2 = albonoursin + H2O2

Direction not assertedBalancedRhea 35539

3-phosphooxypyruvate + H2O = 3-hydroxypyruvate + phosphate

Direction not assertedBalancedRhea 35543

cyclo(L-tyrosyl-L-tyrosyl) + 2 reduced [2Fe-2S]-[ferredoxin] + O2 + 2 H(+) = mycoclysin + 2 oxidized [2Fe-2S]-[ferredoxin] + 2 H2O

Direction not assertedBalance undeterminableRhea 35547

cyclo(L-leucyl-L-leucyl) + 6 reduced [2Fe-2S]-[ferredoxin] + 3 O2 + 4 H(+) = pulcherriminic acid + 6 oxidized [2Fe-2S]-[ferredoxin] + 4 H2O

Direction not assertedBalance undeterminableRhea 35555

menaquinone-7 + NADH + H(+) = menaquinol-7 + NAD(+)

Direction not assertedBalancedRhea 35559

N-(9Z-hexadecenoyl) ethanolamine + H2O = (9Z)-hexadecenoate + ethanolamine

Left to rightBalancedRhea 35563

N-(9Z,12Z-octadecadienoyl)-ethanolamine + H2O = ethanolamine + (9Z,12Z)-octadecadienoate

Direction not assertedBalancedRhea 35567

(1'S)-averantin + reduced [NADPH--hemoprotein reductase] + O2 = (1'S,5'S)-5'-hydroxyaverantin + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 35571

(1'S)-averantin + reduced [NADPH--hemoprotein reductase] + O2 = (1'S,5'R)-5'-hydroxyaverantin + oxidized [NADPH--hemoprotein reductase] + H2O

Direction not assertedBalance undeterminableRhea 35575

anthocyanin A8 + 1-O-(trans-sinapoyl)-beta-D-glucose = anthocyanin A11 + D-glucose

Direction not assertedBalancedRhea 35579

2-dehydro-3-deoxy-D-gluconate = D-glyceraldehyde + pyruvate

Direction not assertedBalancedRhea 35583

FMN + H2O = riboflavin + phosphate

Direction not assertedBalancedRhea 35587

n sulfur + H2 = (n-1) sulfur + hydrogen sulfide + H(+)

Direction not assertedBalance undeterminableRhea 35591

benzene-1,2,4-triol + O2 = maleylacetate + 2 H(+)

Direction not assertedBalancedRhea 35595

propane-1,3-diol + NADP(+) = 3-hydroxypropanal + NADPH + H(+)

Direction not assertedBalancedRhea 35599

beta-D-fructose 1-phosphate + H2O = D-fructose + phosphate

Left to rightBalancedRhea 35603

acetoin + NADP(+) = diacetyl + NADPH + H(+)

Right to leftBalancedRhea 35607

menadiol + 2 O2 = menadione + 2 superoxide + 2 H(+)

Direction not assertedBalancedRhea 35611

hydroxyacetone + NAD(+) = methylglyoxal + NADH + H(+)

Direction not assertedBalancedRhea 35615

L-idarate = D-glucarate

Direction not assertedBalancedRhea 35619

D-glutamine + D-glutamate = gamma-D-glutamyl-D-glutamate + NH4(+)

Direction not assertedBalancedRhea 35623

delphinidin 3,5-bis-O-beta-D-glucoside + UDP-alpha-D-glucose = delphinidin 3,3',5-tri-O-beta-D-glucoside + UDP + H(+)

Direction not assertedBalancedRhea 35627

cyanidin + UDP-alpha-D-galactose = cyanidin 3-O-beta-D-galactoside + UDP + H(+)

Direction not assertedBalancedRhea 35631

an anthocyanidin 3-O-[2-O-(4-coumaroyl)-alpha-L-rhamnosyl-(1->6)-beta-D-glucoside] + UDP-alpha-D-glucose = an anthocyanidin 3-O-[2-O-(4-coumaroyl)-alpha-L-rhamnosyl-(1->6)-beta-D-glucoside] 5-O-beta-D-glucoside + UDP + H(+)

Direction not assertedBalance undeterminableRhea 35635

(4S)-4-hydroxy-2-oxoglutarate = glyoxylate + pyruvate

Direction not assertedBalancedRhea 35639

a (2R)-2-hydroxycarboxylate + NAD(+) = a 2-oxocarboxylate + NADH + H(+)

Direction not assertedBalance undeterminableRhea 35643

GTP + ATP = 3',3'-cGAMP + 2 diphosphate

Direction not assertedBalancedRhea 35647

(4R)-hydroxysphinganine + a fatty acyl-CoA = an N-acyl-(4R)-4-hydroxysphinganine + CoA + H(+)

Direction not assertedBalance undeterminableRhea 35651

2 ATP = 3',3'-c-di-AMP + 2 diphosphate

Left to rightBalancedRhea 35655

an N-acyl-(4R)-4-hydroxysphinganine-1-phosphoinositol + GDP-alpha-D-mannose = mannosylinositol phosphorylphytoceramide + GDP + H(+)

Direction not assertedBalance undeterminableRhea 35659

a 1,2-diacyl-sn-glycerol + H2O = a 1-acyl-sn-glycerol + a fatty acid + H(+)

Direction not assertedBalance undeterminableRhea 35663

a triacylglycerol + H2O = a 1,2-diacylglycerol + a fatty acid + H(+)

Left to rightBalance undeterminableRhea 35667

(S)-5'-oxoaverantin + H(+) = (1'S,5'S)-averufin + H2O

Direction not assertedBalancedRhea 35671

tetradecanoyl-CoA + L-serine + H(+) = 3-oxohexadecasphinganine + CO2 + CoA

Left to rightBalancedRhea 35675

dodecanoyl-CoA + L-serine + H(+) = 3-oxotetradecasphinganine + CO2 + CoA

Left to rightBalancedRhea 35679

hexadecasphinganine + NADP(+) = 3-oxohexadecasphinganine + NADPH + H(+)

Direction not assertedBalancedRhea 35683

tetradecasphinganine + NADP(+) = 3-oxotetradecasphinganine + NADPH + H(+)

Direction not assertedBalancedRhea 35687

(2S)-versicolorone + NADP(+) = 1'-hydroxyversicolorone + NADPH + H(+)

Direction not assertedBalancedRhea 35691

Page 119 of 372