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Reference

Evidence

CompoundsSubstances with curated findings
OutcomesMeasured endpoints
ProteinsTransporters and enzymes
InteractionsPairs that share biology
PapersEvery paper a finding cites
ArticlesReadings of the evidence

Chemistry

ReactionsRhea and Human-GEM, by subsystem
ReachWhat a compound can become

Reference layer

PathwaysReactions grouped under one name
ProcessesWhat proteins are annotated as doing
AnatomyTissues, by what is expressed there
Cell typesCells, by what is expressed there
OrganismsSpecies a compound is prepared from
MaterialsSubstances that are not one molecule
AssessmentsRegulatory determinations, transcribed
DiseasesFeatures, genes, and where each sits

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Reference

Evidence

Compounds
Outcomes
Proteins
Interactions
Papers
Articles

Chemistry

Reactions
Reach

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Pathways
Processes
Anatomy
Cell types
Organisms
Materials
Assessments
Diseases

Atlas Graph Twin Access

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

© 2026 CatalystPrivacy TermsReference data under the licences listed on the attribution page.

Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSourceClear

Reactions

5,751–5,800 of 18,558 reactions from Rhea

thiophene-2-carboxylate + ATP + CoA = thiophene-2-carbonyl-CoA + AMP + diphosphate
Direction not assertedBalancedRhea 34867
methanol(out) = methanol(in)
Direction not assertedBalancedTransportRhea 34871
2-oxepin-2(3H)-ylideneacetyl-CoA + NADP(+) + 2 H2O = 3-oxo-5,6-didehydrosuberyl-CoA + NADPH + 2 H(+)
Direction not assertedBalancedRhea 34875
methyl 3-cyano-2-phenylpropanoate + 2 H2O = 4-methoxy-4-oxo-3-phenylbutanoate + NH4(+)
Direction not assertedBalancedRhea 34879
selenate(out) + ATP + H2O = selenate(in) + ADP + phosphate + H(+)
Direction not assertedBalancedTransportRhea 34883
selenate(in) = selenate(out)
Direction not assertedBalancedTransportRhea 34887
selenite(in) = selenite(out)

Direction not assertedBalancedTransportRhea 34891

selenite(out) + ATP + H2O = selenite(in) + ADP + phosphate + H(+)

Direction not assertedBalancedTransportRhea 34895

malonyl-CoA + S-adenosyl-L-methionine = malonyl-CoA methyl ester + S-adenosyl-L-homocysteine

Direction not assertedBalancedRhea 34899

selenite + 4 glutathione + 2 H(+) = selenodiglutathione + glutathione disulfide + 3 H2O

Direction not assertedBalancedRhea 34903

molybdate(in) = molybdate(out)

Direction not assertedBalancedTransportRhea 34907

D-methionine(in) = D-methionine(out)

Direction not assertedBalancedTransportRhea 34911

D-galactose(in) = D-galactose(out)

Direction not assertedBalancedTransportRhea 34915

thiamine(in) = thiamine(out)

Right to leftBalancedTransportRhea 34919

nitrate(in) = nitrate(out)

Direction not assertedBalancedTransportRhea 34923

selenodiglutathione + NADPH + H(+) = glutathioselenol + glutathione + NADP(+)

Direction not assertedBalancedRhea 34927

glutathioselenol + NADPH = hydrogenselenide + glutathione + NADP(+)

Direction not assertedBalancedRhea 34931

2 ATP + H(+) = P(1),P(4)-bis(5'-adenosyl) tetraphosphate + diphosphate

Left to rightBalancedRhea 34935

selenite + menaquinone-8 + H2O = selenate + menaquinol-8

Direction not assertedBalancedRhea 34939

hydroquinone O-beta-D-glucopyranoside(out) + phosphoenolpyruvate(in) = arbutin 6-phosphate(in) + pyruvate(in)

Direction not assertedBalancedRhea 34943

(Z)-3-aminoacrylate + H2O + H(+) = 3-oxopropanoate + NH4(+)

Direction not assertedBalancedRhea 34947

3-hydroxypropanoate(out) = 3-hydroxypropanoate(in)

Direction not assertedBalancedTransportRhea 34951

5-(methylsulfanyl)-D-ribose(in) = 5-(methylsulfanyl)-D-ribose(out)

Direction not assertedBalancedTransportRhea 34955

(R)-carnitine(in) = (R)-carnitine(out)

ReversibleBalancedTransportRhea 34959

Na(+)(in) = Na(+)(out)

Right to leftBalancedTransportRhea 34963

sn-glycerol 3-phosphate(in) = sn-glycerol 3-phosphate(out)

Direction not assertedBalancedTransportRhea 34967

Fe(3+)(in) = Fe(3+)(out)

Direction not assertedBalancedTransportRhea 34971

(R)-pantothenate(in) = (R)-pantothenate(out)

Direction not assertedBalancedTransportRhea 34975

H(+)(in) = H(+)(out)

Left to rightBalancedTransportRhea 34979

sulfate(in) = sulfate(out)

Direction not assertedBalancedTransportRhea 34983

(S)-lactate(in) = (S)-lactate(out)

Direction not assertedBalancedTransportRhea 34987

L-ornithine(in) + L-arginine(out) = L-ornithine(out) + L-arginine(in)

Direction not assertedBalancedTransportRhea 34991

L-rhamnose(in) = L-rhamnose(out)

Direction not assertedBalancedTransportRhea 34995

ADP(in) + ATP(out) = ADP(out) + ATP(in)

ReversibleBalancedTransportRhea 34999

L-fucose(in) = L-fucose(out)

Direction not assertedBalancedTransportRhea 35003

D-fucose(in) = D-fucose(out)

Direction not assertedBalancedTransportRhea 35007

D-fucose(in) + H(+)(in) = D-fucose(out) + H(+)(out)

Direction not assertedBalancedTransportRhea 35011

riboflavin(in) = riboflavin(out)

Direction not assertedBalancedTransportRhea 35015

L-threonine(in) = L-threonine(out)

Direction not assertedBalancedTransportRhea 35019

hydroquinone O-beta-D-glucopyranoside(out) = hydroquinone O-beta-D-glucopyranoside(in)

Direction not assertedBalancedTransportRhea 35023

tungstate(in) + ATP + H2O = tungstate(out) + ADP + phosphate + H(+)

Direction not assertedBalancedTransportRhea 35027

L-serine(in) = L-serine(out)

Left to rightBalancedTransportRhea 35031

4-aminobutanoate(in) = 4-aminobutanoate(out)

Right to leftBalancedTransportRhea 35035

spermidine(in) = spermidine(out)

Direction not assertedBalancedTransportRhea 35039

N-(4-aminobenzoyl)-L-glutamate(in) = N-(4-aminobenzoyl)-L-glutamate(out)

Direction not assertedBalancedTransportRhea 35043

adenylyl-molybdopterin + molybdate = Mo-molybdopterin + AMP + H(+)

Left to rightBalancedRhea 35047

N,N'-diacetylchitobiose(out) = N,N'-diacetylchitobiose(in)

Direction not assertedBalancedTransportRhea 35051

3,6-dichlorocatechol + O2 = (2E,4E)-2,5-dichloromuconate + H(+)

Direction not assertedBalancedRhea 35055

chloramphenicol(in) + H(+)(out) = chloramphenicol(out) + H(+)(in)

Direction not assertedBalancedTransportRhea 35059

pyrazinamide + H2O = pyrazine-2-carboxylate + NH4(+)

Direction not assertedBalancedRhea 35063

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