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CompoundsSubstances with curated findings
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ProteinsTransporters and enzymes
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ReactionsRhea and Human-GEM, by subsystem
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PathwaysReactions grouped under one name
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Reference

Evidence

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

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Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSourceClear

Reactions

5,701–5,750 of 18,558 reactions from Rhea

C30 botryococcene + 2 S-adenosyl-L-methionine = 3,20-dimethyl-1,2,21,22-tetradehydro-2,3,20,21-tetrahydrobotryococcene + 2 S-adenosyl-L-homocysteine + 2 H(+)
Direction not assertedBalancedRhea 34655
C30 botryococcene + S-adenosyl-L-methionine = 3-methyl-1,2-didehydro-2,3-dihydrobotryococcene + S-adenosyl-L-homocysteine + H(+)
Direction not assertedBalancedRhea 34659
20-methyl-21,22-didehydro-20,21-dihydrobotryococcene + S-adenosyl-L-methionine = 3,20-dimethyl-1,2,21,22-tetradehydro-2,3,20,21-tetrahydrobotryococcene + S-adenosyl-L-homocysteine + H(+)
Direction not assertedBalancedRhea 34663
C30 botryococcene + S-adenosyl-L-methionine = 20-methyl-21,22-didehydro-20,21-dihydrobotryococcene + S-adenosyl-L-homocysteine + H(+)
Direction not assertedBalancedRhea 34667
3-methyl-1,2-didehydro-2,3-dihydrobotryococcene + S-adenosyl-L-methionine = 3,20-dimethyl-1,2,21,22-tetradehydro-2,3,20,21-tetrahydrobotryococcene + S-adenosyl-L-homocysteine + H(+)
Direction not assertedBalancedRhea 34671
N,N-diacetyllegionaminate + CTP = CMP-N,N-diacetyllegionaminate + diphosphate

Direction not assertedBalancedRhea 34675

methylphosphonate + ATP = alpha-D-ribose 1-methylphosphonate 5-triphosphate + adenine

Direction not assertedBalancedRhea 34679

alpha-D-ribose 1-methylphosphonate 5-triphosphate + H2O = alpha-D-ribose 1-methylphosphonate 5-phosphate + diphosphate + H(+)

Direction not assertedBalancedRhea 34683

(R)-lactoyl-CoA = acryloyl-CoA + H2O

Direction not assertedBalancedRhea 34691

(2E,6E)-farnesyl diphosphate = Delta(6)-protoilludene + diphosphate

Direction not assertedBalancedRhea 34695

(2E,6E)-farnesyl diphosphate = (-)-alpha-isocomene + diphosphate

Direction not assertedBalancedRhea 34699

(2E,6E)-farnesyl diphosphate = (E)-2-epi-beta-caryophyllene + diphosphate

Direction not assertedBalancedRhea 34703

alpha-D-ribose 1-methylphosphonate 5-phosphate + AH2 + S-adenosyl-L-methionine = alpha-D-ribose 1,2-cyclic phosphate 5-phosphate + methane + 5'-deoxyadenosine + L-methionine + A + H(+)

Direction not assertedBalancedRhea 34707

an N-acyl-15-methylhexadecasphing-4-enine + H2O = 15-methylhexadecasphing-4-enine + a fatty acid

Direction not assertedBalance undeterminableRhea 34711

15-methylhexadecasphing-4-enine + ATP = 15-methylhexadecasphing-4-enine 1-phosphate + ADP + H(+)

Direction not assertedBalancedRhea 34715

15-methylhexadecasphing-4-enine 1-phosphate = (2E)-13-methyltetradecenal + phosphoethanolamine

Direction not assertedBalancedRhea 34719

15-methylhexadecasphing-4-enine 1-phosphate + H2O = 15-methylhexadecasphing-4-enine + phosphate

Direction not assertedBalancedRhea 34723

an N-acyl-15-methylhexadecasphinganine + H2O = 15-methylhexadecasphinganine + a carboxylate

Direction not assertedBalance undeterminableRhea 34727

15-methylhexadecasphing-4-enine + a fatty acyl-CoA = an N-acyl-15-methylhexadecasphing-4-enine + CoA + H(+)

Direction not assertedBalance undeterminableRhea 34731

a fatty acyl-CoA + sphinganine = an N-acylsphinganine + CoA + H(+)

Left to rightBalance undeterminableRhea 34735

an N-acyl-15-methylhexadecasphing-4-enine-1-phosphocholine + H2O = an N-acyl-15-methylhexadecasphing-4-enine + phosphocholine + H(+)

Direction not assertedBalance undeterminableRhea 34739

15-methylhexadecasphinganine 1-phosphate = 13-methyltetradecanal + phosphoethanolamine

Direction not assertedBalancedRhea 34743

15-methylhexadecasphinganine + ATP = 15-methylhexadecasphinganine 1-phosphate + ADP + H(+)

Direction not assertedBalancedRhea 34747

an N-acyl-15-methylhexadecasphing-4-enine + ATP = an N-acyl-15-methylhexadecasphing-4-enine-1-phosphate + ADP + H(+)

Direction not assertedBalance undeterminableRhea 34751

an N-acyl-1-beta-D-glucosyl-15-methylhexadecasphing-4-enine + H2O = an N-acyl-15-methylhexadecasphing-4-enine + D-glucose

Direction not assertedBalance undeterminableRhea 34755

glycerol 2-phosphate(out) + ATP + H2O = glycerol 2-phosphate(in) + ADP + phosphate + H(+)

Direction not assertedBalancedTransportRhea 34759

(S,S)-tartrate(out) + succinate(in) = (S,S)-tartrate(in) + succinate(out)

Direction not assertedBalancedTransportRhea 34763

(6R)-5,10-methenyltetrahydrofolate + H2O = (6S)-5-formyl-5,6,7,8-tetrahydrofolate + H(+)

Left to rightBalancedRhea 34767

a 3beta-hydroxysteroid-4alpha-carboxylate + NADP(+) = a 3-oxosteroid + CO2 + NADPH

Direction not assertedBalance undeterminableRhea 34771

a 3beta-hydroxysteroid-4alpha-carboxylate + NAD(+) = a 3-oxosteroid + CO2 + NADH

Direction not assertedBalance undeterminableRhea 34775

a 3alpha-hydroxysteroid + NAD(+) = a 3-oxosteroid + NADH + H(+)

Direction not assertedBalance undeterminableRhea 34779

a 3alpha-hydroxysteroid + NADP(+) = a 3-oxosteroid + NADPH + H(+)

Right to leftBalance undeterminableRhea 34783

a 3beta-hydroxysteroid + NADP(+) = a 3-oxosteroid + NADPH + H(+)

Right to leftBalance undeterminableRhea 34787

2-hydroxyethylphosphonate + O2 = hydroxymethylphosphonate + formate + H(+)

Direction not assertedBalancedRhea 34791

alpha-D-ribose 1,2-cyclic phosphate 5-phosphate + H2O = alpha-D-ribose 1,5-bisphosphate + H(+)

Direction not assertedBalancedRhea 34795

2,3-didehydroadipoyl-CoA + acetyl-CoA = 3-oxo-5,6-didehydrosuberyl-CoA + CoA

Direction not assertedBalancedRhea 34799

2 4-coumaroyl-CoA + malonyl-CoA + H2O + H(+) = bisdemethoxycurcumin + 2 CO2 + 3 CoA

Direction not assertedBalancedRhea 34803

(R)-dihydrocamalexate + reduced [NADPH--hemoprotein reductase] + O2 = camalexin + oxidized [NADPH--hemoprotein reductase] + CO2 + 2 H2O

Direction not assertedBalance undeterminableRhea 34807

tetrahydrocurcumin + NADP(+) = dihydrocurcumin + NADPH + H(+)

Direction not assertedBalancedRhea 34811

tetrahydrocurcumin + 2 NADP(+) = curcumin + 2 NADPH + 2 H(+)

Direction not assertedBalancedRhea 34815

dihydrocurcumin + NADP(+) = curcumin + NADPH + H(+)

Direction not assertedBalancedRhea 34819

(E)-feruloylacetyl-CoA + (E)-feruloyl-CoA + H2O = curcumin + CO2 + 2 CoA

Direction not assertedBalancedRhea 34823

an N-acyl-15-methylhexadecasphing-4-enine-1-phosphate + H2O = an N-acyl-15-methylhexadecasphing-4-enine + phosphate

Direction not assertedBalance undeterminableRhea 34831

an N-acyl-4-hydroxy-15-methylhexadecasphinganine + a 1,2-diacyl-sn-glycero-3-phosphocholine = N-acyl-4-hydroxy-15-methylhexadecasphinganine-1-phosphocholine + a 1,2-diacyl-sn-glycerol

Direction not assertedBalance undeterminableRhea 34835

5 malonyl-CoA + 4 H(+) = 5,7-dihydroxy-2-methyl-4H-chromen-4-one + 5 CO2 + 5 CoA + H2O

Direction not assertedBalancedRhea 34839

7,8-dihydromonapterin 3'-triphosphate + 3 H2O = 7,8-dihydromonapterin + 3 phosphate + 2 H(+)

Direction not assertedBalancedRhea 34843

7,8-dihydromonapterin + NADPH + H(+) = 5,6,7,8-tetrahydromonapterin + NADP(+)

Direction not assertedBalancedRhea 34847

(3S)-3-hydroxyadipyl-CoA + NAD(+) = 3-oxoadipyl-CoA + NADH + H(+)

Direction not assertedBalancedRhea 34851

iminodiacetonitrile + 2 H2O = N-(cyanomethyl)glycine + NH4(+)

Direction not assertedBalancedRhea 34855

3-oxocyclopentanecarbonitrile + 2 H2O = 3-oxocyclopentanecarboxylate + NH4(+)

Direction not assertedBalancedRhea 34859

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