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CompoundsSubstances with curated findings
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ProteinsTransporters and enzymes
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ReactionsRhea and Human-GEM, by subsystem
ReachWhat a compound can become

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PathwaysReactions grouped under one name
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AnatomyTissues, by what is expressed there
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Reference

Evidence

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

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Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSourceClear

Reactions

5,651–5,700 of 18,558 reactions from Rhea

dTDP-6-deoxy-beta-L-talose = dTDP-beta-L-rhamnose
Direction not assertedBalancedRhea 34451
all-trans-beta-carotene = 9-cis-beta-carotene
Direction not assertedBalancedRhea 34455
8-hydroxycopalyl diphosphate + H2O = sclareol + diphosphate
Direction not assertedBalancedRhea 34459
8-hydroxycopalyl diphosphate = cis-abienol + diphosphate
Direction not assertedBalancedRhea 34463
(2E,6E)-farnesyl diphosphate = valerena-4,7(11)-diene + diphosphate
Direction not assertedBalancedRhea 34467
propanoyl-CoA + NAD(+) = acryloyl-CoA + NADH + H(+)
Direction not assertedBalancedRhea 34471
2 (2E,6E,10E)-geranylgeranyl diphosphate = 15-cis-phytoene + 2 diphosphate

? Direction not asserted

Balanced

Rhea 34475

(1R,2R,3R)-prephytoene diphosphate = 15-cis-phytoene + diphosphate

Direction not assertedBalancedRhea 34479

4-coumaroyl-CoA + malonyl-CoA + H2O + H(+) = 4-hydroxybenzalacetone + 2 CO2 + 2 CoA

Direction not assertedBalancedRhea 34483

N-acetyl-alpha-D-glucosaminyl-1-diphospho-trans,octa-cis-decaprenol + dTDP-beta-L-rhamnose = alpha-L-rhamnosyl-(1->3)-N-acetyl-alpha-D-glucosaminyl-diphospho-trans,octa-cis-decaprenol + dTDP + H(+)

Direction not assertedBalancedRhea 34487

UDP-N,N'-diacetylbacillosamine + H2O = 2,4-diacetamido-2,4,6-trideoxy-alpha-D-mannopyranose + UDP + H(+)

Direction not assertedBalancedRhea 34491

(9Z,12Z,15Z)-octadecatrienoate + O2 = (13S)-hydroperoxy-(9Z,11E,15Z)-octadecatrienoate

Direction not assertedBalancedRhea 34495

1-deoxypentalenate + reduced 2[4Fe-4S]-[ferredoxin] + O2 + 2 H(+) = pentalenate + oxidized 2[4Fe-4S]-[ferredoxin] + H2O

Direction not assertedBalance undeterminableRhea 34499

(2E,6E)-farnesyl diphosphate + H2O = (+)-epi-alpha-bisabolol + diphosphate

Direction not assertedBalancedRhea 34503

2,4-diacetamido-2,4,6-trideoxy-alpha-D-mannopyranose + phosphoenolpyruvate + H2O = N,N-diacetyllegionaminate + phosphate

Direction not assertedBalancedRhea 34507

N,N'-diacetyl-alpha-D-bacillosaminyl-tri-trans,hepta-cis-undecaprenyl diphosphate + UDP-N-acetyl-alpha-D-galactosamine = N-acetyl-alpha-D-galactosaminyl-(1->3)-N,N'-diacetyl-alpha-D-bacillosaminyl-tri-trans,hepta-cis-undecaprenyl diphosphate + UDP + H(+)

Direction not assertedBalancedRhea 34511

tri-trans,hepta-cis-undecaprenyl phosphate + UDP-N,N'-diacetylbacillosamine = N,N'-diacetyl-alpha-D-bacillosaminyl-tri-trans,hepta-cis-undecaprenyl diphosphate + UMP

Direction not assertedBalancedRhea 34515

N-acetyl-alpha-D-galactosaminyl-(1->4)-N-acetyl-alpha-D-galactosaminyl-(1->3)-N,N'-diacetyl-alpha-D-bacillosaminyl-tri-trans,heptacis-undecaprenyl diphosphate + 3 UDP-N-acetyl-alpha-D-galactosamine = [alpha-D-GalNAc-(1->4)]4-alpha-D-GalNAc-(1->3)-alpha-D-diNAcBac-tri-trans,hepta-cis-undecaprenyl diphosphate + 3 UDP + 3 H(+)

Direction not assertedBalancedRhea 34519

[alpha-D-GalNAc-(1->4)]4-alpha-D-GalNAc-(1->3)-alpha-D-diNAcBac-tri-trans,hepta-cis-undecaprenyl diphosphate + UDP-alpha-D-glucose = [alpha-D-GalNAc-(1->4)]2-[beta-D-Glc-(1->3)]-[alpha-D-GalNAc-(1->4)]2-alpha-D-GalNAc-(1->3)-alpha-D-diNAcBac-tri-trans,hepta-cis-undecaprenyl diphosphate + UDP + H(+)

Direction not assertedBalancedRhea 34523

L-phenylalanine = (S)-3-amino-3-phenylpropanoate

Direction not assertedBalancedRhea 34527

dTDP-4-amino-4,6-dideoxy-alpha-D-glucose + acetyl-CoA = dTDP-4-acetamido-4,6-dideoxy-alpha-D-glucose + CoA + H(+)

Direction not assertedBalancedRhea 34531

hexadecanoyl-CoA + L-alanine + H(+) = 1-deoxy-3-dehydrosphinganine + CO2 + CoA

Direction not assertedBalancedRhea 34535

tellurite + S-adenosyl-L-methionine = methanetellurite + S-adenosyl-L-homocysteine

Direction not assertedBalancedRhea 34539

N-acetyl-alpha-D-galactosaminyl-(1->3)-N,N'-diacetyl-alpha-D-bacillosaminyl-tri-trans,hepta-cis-undecaprenyl diphosphate + UDP-N-acetyl-alpha-D-galactosamine = N-acetyl-alpha-D-galactosaminyl-(1->4)-N-acetyl-alpha-D-galactosaminyl-(1->3)-N,N'-diacetyl-alpha-D-bacillosaminyl-tri-trans,heptacis-undecaprenyl diphosphate + UDP + H(+)

Direction not assertedBalancedRhea 34543

cob(II)yrinate + L-glutamine + ATP + H2O = cob(II)yrinate c monoamide + L-glutamate + ADP + phosphate + H(+)

Direction not assertedBalancedRhea 34547

cob(II)yrinate c monoamide + L-glutamine + ATP + H2O = cob(II)yrinate a,c diamide + L-glutamate + ADP + phosphate + H(+)

Direction not assertedBalancedRhea 34551

a (2S)-2-hydroxycarboxylate + NAD(+) = a 2-oxocarboxylate + NADH + H(+)

Direction not assertedBalance undeterminableRhea 34555

1-deoxy-11beta-hydroxypentalenate + NAD(+) = 1-deoxy-11-oxopentalenate + NADH + H(+)

Direction not assertedBalancedRhea 34559

CDP-alpha-D-abequose + NADP(+) = CDP-4-dehydro-3,6-dideoxy-alpha-D-glucose + NADPH + H(+)

Direction not assertedBalancedRhea 34563

CDP-alpha-D-paratose + NADP(+) = CDP-4-dehydro-3,6-dideoxy-alpha-D-glucose + NADPH + H(+)

Direction not assertedBalancedRhea 34567

C30 botryococcene + diphosphate + NADP(+) = presqualene diphosphate + NADPH + H(+)

Direction not assertedBalancedRhea 34571

pentalenolactone F + 2 reduced [2Fe-2S]-[ferredoxin] + O2 + 2 H(+) = pentalenolactone + 2 oxidized [2Fe-2S]-[ferredoxin] + 2 H2O

Direction not assertedBalance undeterminableRhea 34575

pentalenolactone D + 2 2-oxoglutarate + 2 O2 = pentalenolactone F + 2 succinate + 2 CO2 + H2O

Direction not assertedBalancedRhea 34579

pentalenolactone D + 2-oxoglutarate + O2 = pentalenolactone E + succinate + CO2 + H2O

Direction not assertedBalancedRhea 34583

pentalenolactone E + 2-oxoglutarate + O2 = pentalenolactone F + succinate + CO2

Direction not assertedBalancedRhea 34587

Co-precorrin-7 + S-adenosyl-L-methionine = Co-precorrin-8X + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 34591

isopentadecanoyl-CoA + L-serine + H(+) = 3-dehydro-15-methylhexadecasphinganine + CO2 + CoA

Direction not assertedBalancedRhea 34595

15-methylhexadecasphinganine + NADP(+) = 3-dehydro-15-methylhexadecasphinganine + NADPH + H(+)

Direction not assertedBalancedRhea 34599

15-methylhexadecasphinganine + a fatty acyl-CoA = an N-acyl-15-methylhexadecasphinganine + CoA + H(+)

Direction not assertedBalance undeterminableRhea 34603

an N-acyl-15-methylhexadecasphing-4-enine + a 1,2-diacyl-sn-glycero-3-phosphocholine = an N-acyl-15-methylhexadecasphing-4-enine-1-phosphocholine + a 1,2-diacyl-sn-glycerol

Direction not assertedBalance undeterminableRhea 34607

an N-acyl-15-methylhexadecasphing-4-enine + UDP-alpha-D-glucose = an N-acyl-1-beta-D-glucosyl-15-methylhexadecasphing-4-enine + UDP + H(+)

Direction not assertedBalance undeterminableRhea 34611

2-hydroxyethylphosphonate + O2 = methylphosphonate + hydrogencarbonate + H(+)

Direction not assertedBalancedRhea 34615

1-deoxypentalenate + 2-oxoglutarate + O2 = 1-deoxy-11beta-hydroxypentalenate + succinate + CO2

Direction not assertedBalancedRhea 34619

(25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-al + 2 reduced [adrenodoxin] + O2 + H(+) = (25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oate + 2 oxidized [adrenodoxin] + H2O

Left to rightBalance undeterminableRhea 34627

5beta-cholestane-3alpha,7alpha,12alpha-triol + 6 reduced [adrenodoxin] + 3 O2 + 5 H(+) = (25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oate + 6 oxidized [adrenodoxin] + 4 H2O

Left to rightBalance undeterminableRhea 34631

1-deoxy-11-oxopentalenate + NADPH + O2 + H(+) = pentalenolactone D + NADP(+) + H2O

Direction not assertedBalancedRhea 34635

1-deoxy-11-oxopentalenate + NADPH + O2 + H(+) = neopentalenolactone D + NADP(+) + H2O

Direction not assertedBalancedRhea 34639

squalene + 2 S-adenosyl-L-methionine = 3,22-dimethyl-1,2,23,24-tetradehydro-2,3,22,23-tetrahydrosqualene + 2 S-adenosyl-L-homocysteine + 2 H(+)

Direction not assertedBalancedRhea 34643

squalene + S-adenosyl-L-methionine = 3-methyl-1,2-didehydro-2,3-dihydrosqualene + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 34647

3-methyl-1,2-didehydro-2,3-dihydrosqualene + S-adenosyl-L-methionine = 3,22-dimethyl-1,2,23,24-tetradehydro-2,3,22,23-tetrahydrosqualene + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 34651

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