Skip to content

Reference

Evidence

CompoundsSubstances with curated findings
OutcomesMeasured endpoints
ProteinsTransporters and enzymes
InteractionsPairs that share biology
PapersEvery paper a finding cites
ArticlesReadings of the evidence

Chemistry

ReactionsRhea and Human-GEM, by subsystem
ReachWhat a compound can become

Reference layer

PathwaysReactions grouped under one name
ProcessesWhat proteins are annotated as doing
AnatomyTissues, by what is expressed there
Cell typesCells, by what is expressed there
OrganismsSpecies a compound is prepared from
MaterialsSubstances that are not one molecule
AssessmentsRegulatory determinations, transcribed
DiseasesFeatures, genes, and where each sits

Atlas Graph Twin Access

Search the graph

Reference

Evidence

Compounds
Outcomes
Proteins
Interactions
Papers
Articles

Chemistry

Reactions
Reach

Reference layer

Pathways
Processes
Anatomy
Cell types
Organisms
Materials
Assessments
Diseases

Atlas Graph Twin Access

Loading the page.

Catalyst

Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

The graph

Compounds
Outcomes
Proteins
Atlas
Interactions
Papers
Articles
Graph
Search

Reference layer

Pathways
Processes
Anatomy
Cell types
Organisms
Materials
Assessments
Diseases
Reactions
Reach

How it works

Mission
Method
Twin
How to read the evidence
Sources and licences

Build on it

Access
In your assistant
For agents
Query the graph
Bulk export

A reference for what the literature reports. Not medical advice.

© 2026 CatalystPrivacy TermsReference data under the licences listed on the attribution page.

Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSourceClear

Reactions

5,601–5,650 of 18,558 reactions from Rhea

5-nitrosalicylate + O2 = 4-nitro-6-oxohepta-2,4-dienedioate + H(+)
Direction not assertedBalancedRhea 34231
4-nitro-6-oxohepta-2,4-dienedioate = 2-oxo-3-(5-oxofuran-2-ylidene)propanoate + nitrite
Direction not assertedBalancedRhea 34235
L-glutamate = 3-aminopentanedioate
Direction not assertedBalancedRhea 34239
Mo-molybdopterin + GTP + H(+) = Mo-molybdopterin guanine dinucleotide + diphosphate
Direction not assertedBalancedRhea 34243
1-deoxymethyl-sphinganine + NADP(+) = 1-deoxymethyl-3-dehydrosphinganine + NADPH + H(+)
Direction not assertedBalancedRhea 34247
1-deoxysphinganine + NADP(+) = 1-deoxy-3-dehydrosphinganine + NADPH + H(+)
Direction not assertedBalancedRhea 34251
sporulenol = (R)-tetraprenyl-beta-curcumene + H2O

Direction not assertedBalancedRhea 34255

(+)-larreatricin + AH2 + O2 = (+)-3'-hydroxylarreatricin + A + H2O

Direction not assertedBalancedRhea 34259

fumigaclavine A + dimethylallyl diphosphate = fumigaclavine C + diphosphate

Direction not assertedBalancedRhea 34263

fumigaclavine B + acetyl-CoA = fumigaclavine A + CoA

Direction not assertedBalancedRhea 34267

2-nitroimidazole + H2O = 1,3-dihydro-2H-imidazol-2-one + nitrite + H(+)

Direction not assertedBalancedRhea 34271

2-deoxy-scyllo-inosamine + S-adenosyl-L-methionine = 3-amino-2,3-dideoxy-scyllo-inosose + 5'-deoxyadenosine + L-methionine + H(+)

Direction not assertedBalancedRhea 34275

a di-trans,poly-cis-dolichol + NADP(+) = a di-trans,poly-cis-polyprenol + NADPH + H(+)

Direction not assertedBalance undeterminableRhea 34279

2 L-tyrosine + O2 = 2 L-dopa

Direction not assertedBalancedRhea 34283

2 L-dopa + O2 = 2 L-dopaquinone + 2 H2O

Left to rightBalancedRhea 34287

2',4,4',6'-tetrahydroxychalcone + UDP-alpha-D-glucose = 2',4,4',6'-tetrahydroxychalcone 4'-O-beta-D-glucoside + UDP + H(+)

Direction not assertedBalancedRhea 34291

2',3,4,4',6'-pentahydroxychalcone + UDP-alpha-D-glucose = 2',3,4,4',6'-pentahydroxychalcone 4'-O-beta-D-glucoside + UDP + H(+)

Direction not assertedBalancedRhea 34295

2'-deamino-2'-hydroxyneamine + 2-oxoglutarate = 2'-deamino-2'-hydroxy-6'-dehydroparomamine + L-glutamate

Direction not assertedBalancedRhea 34299

L-lysine = L-pipecolate + NH4(+)

Direction not assertedBalancedRhea 34303

4-nitrocatechol + NADPH + O2 = 2-hydroxy-1,4-benzoquinone + nitrite + NADP(+) + H2O

Direction not assertedBalancedRhea 34307

4-nitrocatechol + NADH + O2 = 2-hydroxy-1,4-benzoquinone + nitrite + NAD(+) + H2O

Direction not assertedBalancedRhea 34311

4-nitrophenol + NADPH + O2 + H(+) = 1,4-benzoquinone + nitrite + NADP(+) + H2O

Direction not assertedBalancedRhea 34327

indole-3-pyruvate + NADPH + O2 + H(+) = (indol-3-yl)acetate + CO2 + NADP(+) + H2O

Direction not assertedBalancedRhea 34331

2 reduced [adrenodoxin] + cholesterol + O2 + 2 H(+) = (22R)-hydroxycholesterol + 2 oxidized [adrenodoxin] + H2O

Left to rightBalance undeterminableRhea 34335

(22R)-hydroxycholesterol + 2 reduced [adrenodoxin] + O2 + 2 H(+) = (20R,22R)-20,22-dihydroxycholesterol + 2 oxidized [adrenodoxin] + H2O

Left to rightBalance undeterminableRhea 34339

(20R,22R)-20,22-dihydroxycholesterol + 2 reduced [adrenodoxin] + O2 + 2 H(+) = 4-methylpentanal + pregnenolone + 2 oxidized [adrenodoxin] + 2 H2O

Left to rightBalance undeterminableRhea 34343

(2E)-geraniol + NAD(+) = (2E)-geranial + NADH + H(+)

Direction not assertedBalancedRhea 34347

(2E)-geranial + NAD(+) + H2O = geranate + NADH + 2 H(+)

Direction not assertedBalancedRhea 34351

a 1,2-diacylglycerol + H2O = a 2-acylglycerol + a carboxylate + H(+)

Direction not assertedBalance undeterminableRhea 34359

N-acetyl-alpha-D-galactosamine 1-phosphate + UTP + H(+) = UDP-N-acetyl-alpha-D-galactosamine + diphosphate

Left to rightBalancedRhea 34363

acrylamide + H2O = acrylate + NH4(+)

Direction not assertedBalancedRhea 34367

indole-3-acetamide + H2O = (indol-3-yl)acetate + NH4(+)

Direction not assertedBalancedRhea 34371

4-guanidinobutanamide + H2O = 4-guanidinobutanoate + NH4(+)

Direction not assertedBalancedRhea 34375

alpha-L-rhamnosyl-(1->3)-N-acetyl-alpha-D-glucosaminyl-diphospho-trans,octa-cis-decaprenol + 2 UDP-alpha-D-galactofuranose = beta-D-galactofuranosyl-(1->5)-beta-D-galactofuranosyl-(1->4)-alpha-L-rhamnosyl-(1->3)-N-acetyl-alpha-D-glucosaminyl-diphospho-trans,octa-cis-decaprenol + 2 UDP + 2 H(+)

Direction not assertedBalancedRhea 34379

alpha-L-rhamnosyl-(1->3)-N-acetyl-alpha-D-glucosaminyl-diphospho-trans,octa-cis-decaprenol + UDP-alpha-D-galactofuranose = beta-D-galactofuranosyl-(1->4)-alpha-L-rhamnosyl-(1->3)-N-acetyl-alpha-D-glucosaminyl-diphospho-trans-octa-cis-decaprenol + UDP + H(+)

Direction not assertedBalancedRhea 34383

beta-D-galactofuranosyl-(1->4)-alpha-L-rhamnosyl-(1->3)-N-acetyl-alpha-D-glucosaminyl-diphospho-trans-octa-cis-decaprenol + UDP-alpha-D-galactofuranose = beta-D-galactofuranosyl-(1->5)-beta-D-galactofuranosyl-(1->4)-alpha-L-rhamnosyl-(1->3)-N-acetyl-alpha-D-glucosaminyl-diphospho-trans,octa-cis-decaprenol + UDP + H(+)

Direction not assertedBalancedRhea 34387

beta-D-galactofuranosyl-(1->5)-beta-D-galactofuranosyl-(1->4)-alpha-L-rhamnosyl-(1->3)-N-acetyl-alpha-D-glucosaminyl-diphospho-trans,octa-cis-decaprenol + 28 UDP-alpha-D-galactofuranose = [beta-D-galactofuranosyl-(1->5)-beta-D-galactofuranosyl-(1->6)]14-beta-D-galactofuranosyl-(1->5)-beta-D-galactofuranosyl-(1->4)-alpha-L-rhamnopyranosyl-(1->3)-N-acetyl-alpha-D-glucosaminyl-diphospho-trans,octa-cis-decaprenol + 28 UDP + 28 H(+)

Direction not assertedBalancedRhea 34391

L-phenylalanine = (3R)-beta-phenylalanine

Direction not assertedBalancedRhea 34395

9-cis-beta-carotene + O2 = 9-cis-10'-apo-beta-carotenal + beta-ionone

Direction not assertedBalancedRhea 34399

9-cis-10'-apo-beta-carotenal + 2 O2 = (2E,4E,6E)-7-hydroxy-4-methylhepta-2,4,6-trienal + (11R)-carlactone

Direction not assertedBalancedRhea 34403

3 ATP = 5'-triphosphoadenylyl-(2'->5')-adenylyl-(2'->5')-adenosine + 2 diphosphate

Left to rightBalancedRhea 34407

cannabigerolate + O2 = cannabidiolate + H2O2

Direction not assertedBalancedRhea 34411

(1R,4R)-bornane-2,5-dione + FMNH2 + O2 = (1R,4R)-5-oxo-1,2-campholide + FMN + H2O + H(+)

Direction not assertedBalancedRhea 34415

(+)-lariciresinol + NADP(+) = (+)-pinoresinol + NADPH + H(+)

Direction not assertedBalancedRhea 34419

(-)-secoisolariciresinol + NADP(+) = (+)-lariciresinol + NADPH + H(+)

Direction not assertedBalancedRhea 34423

(-)-lariciresinol + NADP(+) = (-)-pinoresinol + NADPH + H(+)

Direction not assertedBalancedRhea 34427

(+)-secoisolariciresinol + NADP(+) = (-)-lariciresinol + NADPH + H(+)

Direction not assertedBalancedRhea 34431

4-(3-methylbut-2-enyl)-L-tryptophan + S-adenosyl-L-methionine = 4-(3-methylbut-2-enyl)-L-abrine + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 34435

dTDP-4-amino-4,6-dideoxy-alpha-D-galactose + acetyl-CoA = dTDP-4-acetamido-4,6-dideoxy-alpha-D-galactose + CoA + H(+)

Direction not assertedBalancedRhea 34443

dTDP-6-deoxy-beta-L-talose + NAD(+) = dTDP-4-dehydro-beta-L-rhamnose + NADH + H(+)

Direction not assertedBalancedRhea 34447

Page 113 of 372