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CompoundsSubstances with curated findings
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ProteinsTransporters and enzymes
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ReactionsRhea and Human-GEM, by subsystem
ReachWhat a compound can become

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PathwaysReactions grouped under one name
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Reference

Evidence

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Interactions
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Reactions
Reach

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Organisms
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Diseases

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

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Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSourceClear

Reactions

5,501–5,550 of 18,558 reactions from Rhea

3-(4-hydroxycyclohex-2-en-1-ylidene)pyruvate + NADH + H(+) = tetrahydro-4-hydroxyphenylpyruvate + NAD(+)
Direction not assertedBalancedRhea 33823
ergosterol = vitamin D2
Direction not assertedBalancedRhea 33827
N-hexacosanoyl-(4R)-hydroxysphinganine + H2O = hexacosanoate + (4R)-hydroxysphinganine
Direction not assertedBalancedRhea 33835
2-O,3-dimethylflaviolin + (2E)-geranyl diphosphate + H(+) = 7-O-geranyl-2-O,3-dimethylflaviolin + diphosphate
Direction not assertedBalancedRhea 33839
N-tetracosanoylsphinganine + H2O = tetracosanoate + sphinganine
Direction not assertedBalancedRhea 33843
N-tetracosanoyl-(4R)-hydroxysphinganine + H2O = tetracosanoate + (4R)-hydroxysphinganine
Direction not assertedBalancedRhea 33847
N-tetracosanoylsphinganine-(1D-myo-inositol) + GDP-alpha-D-mannose = mannosyl-alpha-1->6-inositol phospho-N-tetracosanoylsphinganine + GDP + H(+)

Direction not assertedBalancedRhea 33851

an inositol-1-phosphophytoceramide + GDP-alpha-D-mannose = a mannosylinositol-1-phosphophytoceramide + GDP + H(+)

Direction not assertedBalance undeterminableRhea 33855

(2S-3S)-versiconal hemiacetal = versicolorin B + H2O

Direction not assertedBalancedRhea 33859

menaquinone-7 + succinate = menaquinol-7 + fumarate

Direction not assertedBalancedRhea 33863

(S)-2-ureidoglycine + glyoxylate = N-carbamoyl-2-oxoglycine + glycine

Direction not assertedBalancedRhea 33867

(S)-2-ureidoglycine + H2O = urea + glyoxylate + NH4(+)

Direction not assertedBalancedRhea 33871

cholesteryl (9Z-octadecenoate) + H2O = cholesterol + (9Z)-octadecenoate + H(+)

Left to rightBalancedRhea 33875

2-deoxy-scyllo-inosamine + NADP(+) = 3-amino-2,3-dideoxy-scyllo-inosose + NADPH + H(+)

Direction not assertedBalancedRhea 33879

2-deoxy-scyllo-inosamine + NAD(+) = 3-amino-2,3-dideoxy-scyllo-inosose + NADH + H(+)

Direction not assertedBalancedRhea 33883

(-)-secoisolariciresinol + 2 NAD(+) = (-)-matairesinol + 2 NADH + 2 H(+)

Direction not assertedBalancedRhea 33887

chanoclavine-I + NAD(+) = chanoclavine-I aldehyde + NADH + H(+)

Direction not assertedBalancedRhea 33891

trans,octa-cis-decaprenylphospho-beta-D-arabinofuranose + NAD(+) = trans,octa-cis-decaprenylphospho-beta-D-erythro-pentofuranosid-2-ulose + NADH + H(+)

Direction not assertedBalancedRhea 33895

trans,octa-cis-decaprenylphospho-beta-D-ribofuranose + FAD + H(+) = trans,octa-cis-decaprenylphospho-beta-D-erythro-pentofuranosid-2-ulose + FADH2

Direction not assertedBalancedRhea 33899

4-(methylamino)butanoate + O2 + H2O = 4-aminobutanoate + formaldehyde + H2O2

Direction not assertedBalancedRhea 33907

an N-alkylglycine + O2 + H2O = an alkylamine + glyoxylate + H2O2

Direction not assertedBalance undeterminableRhea 33911

4-(methylamino)butanoate + O2 + H2O = succinate semialdehyde + methylamine + H2O2

Direction not assertedBalancedRhea 33915

lanosterol + NADPH + H(+) = 24,25-dihydrolanosterol + NADP(+)

Left to rightBalancedRhea 33919

(1R,4R)-5-oxo-1,2-campholide = [(1R)-2,2,3-trimethyl-5-oxocyclopent-3-en-1-yl]acetate + H(+)

Direction not assertedBalancedRhea 33923

4-(6-hydroxypyridin-3-yl)-4-oxobutanoate + 2 NADH + O2 + 2 H(+) = 2,5-dihydroxypyridine + succinate semialdehyde + 2 NAD(+) + H2O

Direction not assertedBalancedRhea 33927

all-trans-zeaxanthin + O2 = (3R)-11-cis-3-hydroxyretinal + (3R)-all-trans-3-hydroxyretinal

Direction not assertedBalancedRhea 33931

2 N(omega)-hydroxy-L-arginine + NADH + 2 O2 = 2 L-citrulline + 2 nitric oxide + NAD(+) + 2 H2O + H(+)

Direction not assertedBalancedRhea 33935

L-arginine + NADH + O2 + H(+) = N(omega)-hydroxy-L-arginine + NAD(+) + H2O

Direction not assertedBalancedRhea 33939

2 L-arginine + 3 NADH + 4 O2 + H(+) = 2 L-citrulline + 2 nitric oxide + 3 NAD(+) + 4 H2O

Direction not assertedBalancedRhea 33943

2-deoxystreptamine + UDP-N-acetyl-alpha-D-glucosamine = 2'-N-acetylparomamine + UDP + H(+)

Direction not assertedBalancedRhea 33947

ribostamycin + UDP-N-acetyl-alpha-D-glucosamine = 2'''-acetyl-6'''-hydroxyneomycin C + UDP + H(+)

Direction not assertedBalancedRhea 33951

DIBOA + UDP-alpha-D-glucose = DIBOA beta-D-glucoside + UDP + H(+)

Direction not assertedBalancedRhea 33955

neomycin C + 2-oxoglutarate = 6'''-deamino-6'''-oxoneomycin C + L-glutamate

Direction not assertedBalancedRhea 33959

isopentenyl phosphate + ATP = isopentenyl diphosphate + ADP

Direction not assertedBalancedRhea 33963

2-oxo-3-(5-oxofuran-2-ylidene)propanoate + H2O = 3-maleylpyruvate + H(+)

Direction not assertedBalancedRhea 33967

5''-phosphoribostamycin + H2O = ribostamycin + phosphate

Direction not assertedBalancedRhea 33971

DIMBOA beta-D-glucoside + H2O = DIMBOA + D-glucose

Direction not assertedBalancedRhea 33975

DIBOA beta-D-glucoside + H2O = DIBOA + D-glucose

Direction not assertedBalancedRhea 33979

(+)-copalyl diphosphate = miltiradiene + diphosphate

Direction not assertedBalancedRhea 33983

(+)-copalyl diphosphate = neoabietadiene + diphosphate

Direction not assertedBalancedRhea 33987

(2E,6E)-farnesyl diphosphate = alpha-copaene + diphosphate

Direction not assertedBalancedRhea 33991

gamma-L-glutamyl-butirosin B = butirosin B + 5-oxo-L-proline

Direction not assertedBalancedRhea 33995

zymosterol = 5alpha-cholesta-7,24-dien-3beta-ol

Left to rightBalancedRhea 33999

5alpha-cholesta-7,24-dien-3beta-ol + NADPH + O2 + H(+) = 7-dehydrodesmosterol + NADP(+) + 2 H2O

Direction not assertedBalancedRhea 34003

7-dehydrodesmosterol + S-adenosyl-L-methionine = 5-dehydroepisterol + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 34007

5-dehydroepisterol + NADP(+) + 2 H2O = ergosta-5,7-dien-3betabeta-ol + NADPH + O2 + H(+)

Direction not assertedBalancedRhea 34011

ergosta-5,7-dien-3betabeta-ol + NADPH + O2 + H(+) = ergosterol + NADP(+) + 2 H2O

Direction not assertedBalancedRhea 34015

a 1-acylglycerol + H2O = glycerol + a fatty acid + H(+)

Left to rightBalance undeterminableRhea 34019

3,3'-bipyridine-2,2',5,5',6,6'-hexol + NAD(+) = (E)-2,2',5,5'-tetrahydroxy-6H,6'H-(3,3'-bipyridinylidene)-6,6'-dione + NADH + 3 H(+)

Direction not assertedBalancedRhea 34023

3,3'-bipyridine-2,2',5,5',6,6'-hexol + NADP(+) = (E)-2,2',5,5'-tetrahydroxy-6H,6'H-(3,3'-bipyridinylidene)-6,6'-dione + NADPH + 3 H(+)

Direction not assertedBalancedRhea 34027

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