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Subsystem: Drug metabolism Remove
501–550 of 572 reactions in Drug metabolism
Gliclazide[c] = Gliclazide[r]
ReversibleBalancedTransportHuman-GEM MAR12953
glucuronide-thiomethyl-acetaminophen conjugate[c] = glucuronide-thiomethyl-acetaminophen conjugate[r]
ReversibleBalancedTransportHuman-GEM MAR12954
ibuprofen-R[c] = ibuprofen-R[r]
ReversibleBalancedTransportHuman-GEM MAR12955
ibuprofen-S[c] = ibuprofen-S[r]
ReversibleBalancedTransportHuman-GEM MAR12956
ibuprofen acyl glucuronide[r] = ibuprofen acyl glucuronide[c]
ReversibleBalancedTransportHuman-GEM MAR12957
Losartan-N1-glucuronide[c] = Losartan-N1-glucuronide[r]
ReversibleBalancedTransportHuman-GEM MAR12958
Losartan[c] = Losartan[r]
ReversibleBalancedTransportHuman-GEM MAR12959
Losartan-M1[c] = Losartan-M1[r]
ReversibleBalancedTransportHuman-GEM MAR12960
Losartan-M2[c] = Losartan-M2[r]
ReversibleBalancedTransportHuman-GEM MAR12961
Losartan-M4 (glucuronide derivative)[c] = Losartan-M4 (glucuronide derivative)[r]
ReversibleBalancedTransportHuman-GEM MAR12962
Losartan-M5[c] = Losartan-M5[r]
ReversibleBalancedTransportHuman-GEM MAR12963
Losartan-N2-glucuronide / Losartan-M7[r] = Losartan-N2-glucuronide / Losartan-M7[c]
ReversibleBalancedTransportHuman-GEM MAR12964
lovastatin lactone form[c] = lovastatin lactone form[r]
ReversibleBalancedTransportHuman-GEM MAR12965
lovastatin-hydroxyacid form[c] = lovastatin-hydroxyacid form[r]
ReversibleBalancedTransportHuman-GEM MAR12967
Midazolam[c] = Midazolam[r]
ReversibleBalancedTransportHuman-GEM MAR12968
Midazolam-glucuronide[r] = Midazolam-glucuronide[c]
ReversibleBalancedTransportHuman-GEM MAR12969
N-desmethyl-rosuvastatin[c] = N-desmethyl-rosuvastatin[r]
ReversibleBalancedTransportHuman-GEM MAR12970
Nitropyridine metabolite of nifedipine[c] = Nitropyridine metabolite of nifedipine[r]
ReversibleBalancedTransportHuman-GEM MAR12971
hydroxy metabolite of nifedipine[r] = hydroxy metabolite of nifedipine[c]
ReversibleBalancedTransportHuman-GEM MAR12972
des-isoproylpropionic-acid-fluvastatin-CoA[x] = des-isoproylpropionic-acid-fluvastatin-CoA[c]
ReversibleBalancedTransportHuman-GEM MAR12973
pitavastatin-lactone[r] = pitavastatin-lactone[c]
ReversibleBalancedTransportHuman-GEM MAR12974
pitavastatin-M13[r] = pitavastatin-M13[c]
ReversibleBalancedTransportHuman-GEM MAR12975
pitavastatin-M13[c] = pitavastatin-M13[e]
ReversibleBalancedTransportHuman-GEM MAR12976
pitavastatin-M3[c] = pitavastatin-M3[r]
ReversibleBalancedTransportHuman-GEM MAR12978
pravastatin[c] = pravastatin[r]
ReversibleBalancedTransportHuman-GEM MAR12979
pravastatin glucuronide[r] = pravastatin glucuronide[c]
ReversibleBalancedTransportHuman-GEM MAR12980
rosuvastatin-5S-lactone[c] = rosuvastatin-5S-lactone[r]
ReversibleBalancedTransportHuman-GEM MAR12981
Tacrolimus[c] = Tacrolimus[r]
ReversibleBalancedTransportHuman-GEM MAR12982
thiomethyl-sulphoxide-conjugate-acetaminophen[r] = thiomethyl-sulphoxide-conjugate-acetaminophen[c]
ReversibleBalancedTransportHuman-GEM MAR12983
trans-lactone-fluvastatin[r] = trans-lactone-fluvastatin[c]
ReversibleBalancedTransportHuman-GEM MAR12984
thiomethyl-conjugate-acetaminophen[r] = thiomethyl-conjugate-acetaminophen[c]
ReversibleBalancedTransportHuman-GEM MAR12985
Torasemide[c] = Torasemide[r]
ReversibleBalancedTransportHuman-GEM MAR12986
Torasemide-M1[r] = Torasemide-M1[c]
ReversibleBalancedTransportHuman-GEM MAR12987
Torasemide-M3[c] = Torasemide-M3[r]
ReversibleBalancedTransportHuman-GEM MAR12988
Torasemide-M5[c] = Torasemide-M5[r]
ReversibleBalancedTransportHuman-GEM MAR12989
thiomethyl-sulphoxide-acetaminophen-glucuronide[c] = thiomethyl-sulphoxide-acetaminophen-glucuronide[r]
ReversibleBalancedTransportHuman-GEM MAR12990
ATP[c] + CoA[c] + 3'-S-hydroxy-pravastatin[c] = AMP[c] + PPi[c] + 3'-S-hydroxy-pravastatin-CoA[c]
Left to rightUnbalancedHuman-GEM MAR12991
H2O[c] + 3'-S-hydroxy-pravastatin-tetranor-CoA[c] = CoA[c] + H+[c] + 3'-S-hydroxy-pravastatin-tetranor[c]
Left to rightUnbalancedHuman-GEM MAR12992
acetaminophen-glutathione-conjugate[r] = glutamate[r] + glycine[r] + cysteine-conjugate-acetaminophen[r]
Left to rightUnbalancedHuman-GEM MAR12993
ATP[c] + CoA[c] + fluvastatin[c] = AMP[c] + PPi[c] + fluvastatin-CoA form[c]
Left to rightUnbalancedHuman-GEM MAR12994
UDP-glucuronate[r] + Midazolam[r] = UDP[r] + Midazolam-glucuronide[r]
Left to rightUnbalancedHuman-GEM MAR12995
5 H+[r] + 6 NADPH[r] + O2[r] + PAPS[r] + SAM[r] + NAPQI[r] = 5 H2O[r] + 6 NADP+[r] + PAP[r] + SAH[r] + thiomethyl-conjugate-acetaminophen[r]
Left to rightBalancedHuman-GEM MAR12996
1'-OH-midazolam[r] = 1'-OH-midazolam[c]
ReversibleBalancedTransportHuman-GEM MAR12997
cysteine-conjugate-acetaminophen[r] = cysteine-conjugate-acetaminophen[c]
ReversibleBalancedTransportHuman-GEM MAR12998
acid metabolite of nifedipine[r] = acid metabolite of nifedipine[c]
ReversibleBalancedTransportHuman-GEM MAR12999
acetaminophen-glutathione-conjugate[c] = acetaminophen-glutathione-conjugate[r]
ReversibleBalancedTransportHuman-GEM MAR13000
H+[r] + NADPH[r] + O2[r] + acetaminophen/paracetamol[r] = 2 H2O[r] + NADP+[r] + NAPQI[r]
Left to rightBalancedHuman-GEM MAR13001
H2O2[r] = H2O2[c]
ReversibleBalancedTransportHuman-GEM MAR13002
H2O[c] + NAD+[c] + UDP-glucuronate[c] = CO2[c] + NADH[c] + udp-ribose[c]
Left to rightBalancedHuman-GEM MAR13003
glycine[r] = glycine[c]
ReversibleBalancedTransportHuman-GEM MAR13004