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ReactionsRhea and Human-GEM, by subsystem
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Reference

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

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Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSourceClear

Reactions

5,401–5,450 of 18,558 reactions from Rhea

glycine + ATP + H(+) = glycyl-5'-AMP + diphosphate
Direction not assertedBalancedRhea 33407
(S)-malyl N-acetyl-alpha-D-glucosaminide + H2O = (S)-malyl alpha-D-glucosaminide + acetate
Direction not assertedBalancedRhea 33411
bornane-2,6-dione + H2O = [(1S)-4-hydroxy-2,2,3-trimethylcyclopent-3-enyl]acetate + H(+)
Direction not assertedBalancedRhea 33415
[(1R)-2,2,3-trimethyl-5-oxocyclopent-3-en-1-yl]acetate + ATP + CoA = [(1R)-2,2,3-trimethyl-5-oxocyclopent-3-enyl]acetyl-CoA + AMP + diphosphate
Direction not assertedBalancedRhea 33419
N,N'-diacetylchitobiose(out) + N(pros)-phospho-L-histidyl-[protein] = diacetylchitobiose-6'-phosphate(in) + L-histidyl-[protein]
Direction not assertedBalance undeterminableRhea 33423
(S)-malyl alpha-D-glucosaminide + L-cysteine = bacillithiol + H2O
Direction not assertedBalancedRhea 33427

(2Z,4E)-2-hydroxyhexa-2,4-dienedioate = (3E)-2-oxohex-3-enedioate

Direction not assertedBalancedRhea 33431

fecosterol = episterol

Direction not assertedBalancedRhea 33435

glyoxal + O2 + H2O = glyoxylate + H2O2 + H(+)

Direction not assertedBalancedRhea 33439

4beta-methylzymosterol-4alpha-carboxylate + NADP(+) = 3-dehydro-4-methylzymosterol + CO2 + NADPH

Left to rightBalancedRhea 33447

N(6),N(6)-dimethyl-L-lysyl-[protein] + A + H2O = N(6)-methyl-L-lysyl-[protein] + formaldehyde + AH2

Direction not assertedBalance undeterminableRhea 33451

4alpha-carboxyzymosterol + NADP(+) = zymosterone + CO2 + NADPH

Left to rightBalancedRhea 33455

zymosterone + NADPH + H(+) = zymosterol + NADP(+)

Left to rightBalancedRhea 33459

episterol + NADPH + O2 + H(+) = 5-dehydroepisterol + NADP(+) + 2 H2O

Direction not assertedBalancedRhea 33463

5-dehydroepisterol + NADPH + O2 + H(+) = ergosta-5,7,22,24(28)-tetraen-3beta-ol + NADP(+) + 2 H2O

Direction not assertedBalancedRhea 33467

an N-acyl-(4R)-4-hydroxysphinganine + a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) = an N-acyl-(4R)-4-hydroxysphinganine-1-phosphoinositol + a 1,2-diacyl-sn-glycerol

Direction not assertedBalance undeterminableRhea 33471

an N-acylsphinganine + a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) = an N-acylsphinganine-(1D-myo-inositol) + a 1,2-diacyl-sn-glycerol

Direction not assertedBalance undeterminableRhea 33475

lanosterol + an acyl-CoA = lanosteryl ester + CoA

Direction not assertedBalance undeterminableRhea 33479

ergosterol + an acyl-CoA = ergosteryl ester + CoA

Direction not assertedBalance undeterminableRhea 33483

2-hydroxyhexacosanoyl-CoA + (4R)-hydroxysphinganine = N-(2-hydroxyhexacosanyl)-(4R)-hydroxysphinganine + CoA + H(+)

Direction not assertedBalancedRhea 33487

2-hydroxyhexacosanoyl-CoA + sphinganine = N-(2-hydroxyhexacosanoyl)-sphinganine + CoA + H(+)

Direction not assertedBalancedRhea 33491

sn-glycerol 1-phosphate + all-trans-heptaprenyl diphosphate = 3-heptaprenyl-sn-glycero-1-phosphate + diphosphate

Direction not assertedBalancedRhea 33495

prephenate + H(+) = 3-[(4R)-4-hydroxycyclohexa-1,5-dien-1-yl]-2-oxopropanoate + CO2

Direction not assertedBalancedRhea 33499

itraconazole(in) + ATP + H2O = itraconazole(out) + ADP + phosphate + H(+)

Direction not assertedBalancedTransportRhea 33503

sphing-4-enine 1-phosphate = (2E)-hexadecenal + phosphoethanolamine

Left to rightBalancedRhea 33507

2 5,6-dihydroxyindole + O2 = 2 indole-5,6-quinone + 2 H2O

Direction not assertedBalancedRhea 33515

sphinganine + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (4R)-hydroxysphinganine + 2 Fe(III)-[cytochrome b5] + H2O

Direction not assertedBalance undeterminableRhea 33519

ergosta-5,7,22,24(28)-tetraen-3beta-yl acetate + H2O = ergosta-5,7,22,24(28)-tetraen-3beta-ol + acetate + H(+)

Direction not assertedBalancedRhea 33523

ergosta-5,7,22,24(28)-tetraen-3beta-ol + acetyl-CoA = ergosta-5,7,22,24(28)-tetraen-3beta-yl acetate + CoA

Direction not assertedBalancedRhea 33527

lanosteryl ester + H2O = lanosterol + a carboxylate + H(+)

Direction not assertedBalance undeterminableRhea 33535

ergosteryl ester + H2O = ergosterol + a carboxylate + H(+)

Direction not assertedBalance undeterminableRhea 33539

ergosteryl hexadecanoate + H2O = ergosterol + hexadecanoate + H(+)

Direction not assertedBalancedRhea 33543

lanosteryl hexadecanoate + H2O = lanosterol + hexadecanoate + H(+)

Direction not assertedBalancedRhea 33547

an N-acylsphinganine + H2O = sphinganine + a fatty acid

Left to rightBalance undeterminableRhea 33551

an N-acyl-(4R)-4-hydroxysphinganine + H2O = (4R)-hydroxysphinganine + a fatty acid

Left to rightBalance undeterminableRhea 33555

sn-glycerol 3-phosphate + an acyl-CoA = a 2-acyl-sn-glycerol 3-phosphate + CoA

Direction not assertedBalance undeterminableRhea 33559

(4R)-hydroxysphinganine + ATP = (4R)-hydroxysphinganine 1-phosphate + ADP + H(+)

Direction not assertedBalancedRhea 33563

ethanol + A = acetaldehyde + AH2

Direction not assertedBalancedRhea 33567

methanol + A = formaldehyde + AH2

Direction not assertedBalancedRhea 33571

an inositol-1-phosphophytoceramide + beta-D-mannose = a mannosylinositol-1-phosphophytoceramide + H2O

Direction not assertedBalance undeterminableRhea 33575

UDP-2-acetamido-2-deoxy-alpha-D-glucuronate + NAD(+) = UDP-2-acetamido-2-deoxy-alpha-D-ribo-hex-3-uluronate + NADH + H(+)

Direction not assertedBalancedRhea 33579

UDP-2-acetamido-2-deoxy-alpha-D-ribo-hex-3-uluronate + L-glutamate = UDP-2-acetamido-3-amino-2,3-dideoxy-alpha-D-glucuronate + 2-oxoglutarate

Direction not assertedBalancedRhea 33583

UDP-2-acetamido-3-amino-2,3-dideoxy-alpha-D-glucuronate + acetyl-CoA = UDP-2,3-diacetamido-2,3-dideoxy-alpha-D-glucuronate + CoA + H(+)

Direction not assertedBalancedRhea 33587

tetracosanoyl-CoA + sphinganine = N-tetracosanoylsphinganine + CoA + H(+)

Left to rightBalancedRhea 33591

tetracosanoyl-CoA + (4R)-hydroxysphinganine = N-tetracosanoyl-(4R)-hydroxysphinganine + CoA + H(+)

Direction not assertedBalancedRhea 33595

N-hexacosanoylsphinganine + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = N-hexacosanoyl-(4R)-hydroxysphinganine + 2 Fe(III)-[cytochrome b5] + H2O

Direction not assertedBalance undeterminableRhea 33599

N-hexacosanoylsphinganine + NADPH + O2 + H(+) = N-(2-hydroxyhexacosanoyl)-sphinganine + NADP(+) + H2O

Direction not assertedBalancedRhea 33603

(9Z)-octadecenoate + ATP + CoA = (9Z)-octadecenoyl-CoA + AMP + diphosphate

Left to rightBalancedRhea 33607

methyl salicylate + H2O = salicylate + methanol + H(+)

Direction not assertedBalancedRhea 33611

octadecanoate + ATP + CoA = octadecanoyl-CoA + AMP + diphosphate

Left to rightBalancedRhea 33615

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