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CompoundsSubstances with curated findings
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ReactionsRhea and Human-GEM, by subsystem
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Reference

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

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Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSourceClear

Reactions

5,301–5,350 of 18,558 reactions from Rhea

a 1-acyl-sn-glycero-3-phospho-(1D-myo-inositol) + H2O = sn-glycero-3-phospho-1D-myo-inositol + a fatty acid + H(+)
Direction not assertedBalance undeterminableRhea 32987
2 a 1-acyl-sn-glycero-3-phosphocholine = sn-glycerol 3-phosphocholine + a 1,2-diacyl-sn-glycero-3-phosphocholine
Left to rightBalance undeterminableRhea 32991
a 1-acyl-sn-glycero-3-phosphoethanolamine + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + CoA
Left to rightBalance undeterminableRhea 32995
(+)-amorpha-4,11-diene + 3 reduced [NADPH--hemoprotein reductase] + 3 O2 = (+)-artemisinate + 3 oxidized [NADPH--hemoprotein reductase] + 4 H2O + 4 H(+)
Direction not assertedBalance undeterminableRhea 32999
(+)-amorpha-4,11-diene + reduced [NADPH--hemoprotein reductase] + O2 = (+)-artemisinic alcohol + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)
Direction not assertedBalance undeterminableRhea 33003
(+)-artemisinic alcohol + reduced [NADPH--hemoprotein reductase] + O2 = (+)-artemisinic aldehyde + oxidized [NADPH--hemoprotein reductase] + 2 H2O + H(+)

? Direction not asserted

Balance undeterminable

Rhea 33007

(+)-artemisinic aldehyde + reduced [NADPH--hemoprotein reductase] + O2 = (+)-artemisinate + oxidized [NADPH--hemoprotein reductase] + H2O + 2 H(+)

Direction not assertedBalance undeterminableRhea 33011

[(1R)-2,2,3-trimethyl-5-oxocyclopent-3-enyl]acetyl-CoA + NADPH + O2 + H(+) = [(2R)-3,3,4-trimethyl-6-oxo-3,6-dihydro-1H-pyran-2-yl]acetyl-CoA + NADP(+) + H2O

Direction not assertedBalancedRhea 33015

(3S)-3,6-diaminohexanoate + acetyl-CoA = (3S)-6-acetamido-3-aminohexanoate + CoA + H(+)

Direction not assertedBalancedRhea 33019

6-phospho-D-gluconate + NAD(+) = D-ribulose 5-phosphate + CO2 + NADH

Direction not assertedBalancedRhea 33023

spheroidene + 4 reduced [2Fe-2S]-[ferredoxin] + 2 O2 + 4 H(+) = spheroiden-2-one + 4 oxidized [2Fe-2S]-[ferredoxin] + 3 H2O

Direction not assertedBalance undeterminableRhea 33027

keto-D-fructose + NADH + H(+) = D-sorbitol + NAD(+)

Right to leftBalancedRhea 33031

2-oxospirilloxanthin + 4 reduced [2Fe-2S]-[ferredoxin] + 2 O2 + 4 H(+) = 2,2'-dioxospirilloxanthin + 4 oxidized [2Fe-2S]-[ferredoxin] + 3 H2O

Direction not assertedBalance undeterminableRhea 33035

spirilloxanthin + 4 reduced [2Fe-2S]-[ferredoxin] + 2 O2 + 4 H(+) = 2-oxospirilloxanthin + 4 oxidized [2Fe-2S]-[ferredoxin] + 3 H2O

Direction not assertedBalance undeterminableRhea 33039

(1R,4R)-camphor + NADPH + O2 + H(+) = (+)-6-exo-hydroxycamphor + NADP(+) + H2O

Direction not assertedBalancedRhea 33043

2 reduced [2Fe-2S]-[putidaredoxin] + (1R,4R)-camphor + O2 + 2 H(+) = (+)-6-endo-hydroxycamphor + 2 oxidized [2Fe-2S]-[putidaredoxin] + H2O

Direction not assertedBalance undeterminableRhea 33047

choline + NAD(+) = betaine aldehyde + NADH + H(+)

Direction not assertedBalancedRhea 33051

guanosine 3'-diphosphate 5'-triphosphate + H2O = GTP + diphosphate + H(+)

Direction not assertedBalancedRhea 33055

(R)-dihydrolipoamide + NAD(+) = (R)-lipoamide + NADH + H(+)

Direction not assertedBalancedRhea 33059

2 reduced [2Fe-2S]-[putidaredoxin] + NAD(+) + H(+) = 2 oxidized [2Fe-2S]-[putidaredoxin] + NADH

Direction not assertedBalance undeterminableRhea 33063

(4R)-hydroxysphinganine 1-phosphate + H2O = (4R)-hydroxysphinganine + phosphate

Left to rightBalancedRhea 33067

D-glucose 6-phosphate = 2-deoxy-L-scyllo-inosose + phosphate

Direction not assertedBalancedRhea 33071

3-[(1-carboxyvinyl)-oxy]benzoate + S-adenosyl-L-methionine + H2O = 6-amino-6-deoxyfutalosine + hydrogencarbonate + L-methionine + H(+)

Direction not assertedBalancedRhea 33075

6-amino-6-deoxyfutalosine + H2O = dehypoxanthine futalosine + adenine

Direction not assertedBalancedRhea 33079

dehypoxanthine futalosine + S-adenosyl-L-methionine = cyclic dehypoxanthinylfutalosinate + 5'-deoxyadenosine + L-methionine + H(+)

Direction not assertedBalancedRhea 33083

cyclic dehypoxanthinylfutalosinate = 1,4-dihydroxy-6-naphthoate + dihydroxyacetone

Direction not assertedBalancedRhea 33087

1,4-dihydroxy-6-naphthoate + all-trans-octaprenyl diphosphate + H(+) = 2-demethylmenaquinol-8 + CO2 + diphosphate

Direction not assertedBalancedRhea 33091

chorismate + inosine + phosphoenolpyruvate = futalosine

Direction not assertedUnbalancedRhea 33095

spermine + acetyl-CoA = N(1)-acetylspermine + CoA + H(+)

Left to rightBalancedRhea 33099

(2E,6E)-farnesyl diphosphate = alpha-muurolene + diphosphate

Direction not assertedBalancedRhea 33103

(2E,6E)-farnesyl diphosphate = gamma-muurolene + diphosphate

Direction not assertedBalancedRhea 33107

(2E,6E)-farnesyl diphosphate = beta-copaene + diphosphate

Direction not assertedBalancedRhea 33111

malonate(in) = malonate(out)

Direction not assertedBalancedTransportRhea 33115

(2E,6E)-farnesyl diphosphate = (+)-sativene + diphosphate

Direction not assertedBalancedRhea 33119

all-trans-heptaprenyl diphosphate = (R)-tetraprenyl-beta-curcumene + diphosphate

Direction not assertedBalancedRhea 33123

salicin-6-phosphate + H2O = salicyl alcohol + beta-D-glucose 6-phosphate

Direction not assertedBalancedRhea 33127

tetrahydro-4-hydroxyphenylpyruvate + L-phenylalanine = tetrahydrotyrosine + 3-phenylpyruvate

Direction not assertedBalancedRhea 33131

malonate(in) + Na(+)(in) = malonate(out) + Na(+)(out)

Direction not assertedBalancedTransportRhea 33135

L-aspartate(in) + L-alanine(out) = L-aspartate(out) + L-alanine(in)

Direction not assertedBalancedTransportRhea 33139

galactitol(in) = galactitol(out)

Direction not assertedBalancedTransportRhea 33143

daunorubicin(in) + ATP + H2O = daunorubicin(out) + ADP + phosphate + H(+)

Left to rightBalancedTransportRhea 33147

(R)-dihydrolipoamide + acetyl-CoA = (R)-S(6)-acetyldihydrolipoamide + CoA

Direction not assertedBalancedRhea 33151

a 1-acyl-sn-glycero-3-phosphate + H2O = a 1-acyl-sn-glycerol + phosphate

Left to rightBalance undeterminableRhea 33155

an N-acyl-1,2-diacyl-sn-glycero-3-phosphoethanolamine + H2O = an N-acylethanolamine + a 1,2-diacyl-sn-glycero-3-phosphate + H(+)

Left to rightBalance undeterminableRhea 33159

beta-nicotinamide D-riboside(in) = beta-nicotinamide D-riboside(out)

Direction not assertedBalancedTransportRhea 33163

2 a 1-acyl-sn-glycero-3-phospho-(1D-myo-inositol) = sn-glycero-3-phospho-1D-myo-inositol + a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol)

Direction not assertedBalance undeterminableRhea 33167

D-maltose(in) = D-maltose(out)

Direction not assertedBalancedTransportRhea 33171

4-hydroxyphenylacetate(in) = 4-hydroxyphenylacetate(out)

Direction not assertedBalancedTransportRhea 33175

a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + H2O = 1D-myo-inositol 1,4,5-trisphosphate + a 1,2-diacyl-sn-glycerol + H(+)

Left to rightBalance undeterminableRhea 33179

citrate(in) = citrate(out)

Left to rightBalancedTransportRhea 33183

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