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CompoundsSubstances with curated findings
OutcomesMeasured endpoints
ProteinsTransporters and enzymes
InteractionsPairs that share biology
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ReactionsRhea and Human-GEM, by subsystem
ReachWhat a compound can become

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PathwaysReactions grouped under one name
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AnatomyTissues, by what is expressed there
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MaterialsSubstances that are not one molecule
AssessmentsRegulatory determinations, transcribed
DiseasesFeatures, genes, and where each sits

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Reference

Evidence

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Reach

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

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Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSourceClear

Reactions

5,251–5,300 of 18,558 reactions from Rhea

glycine betaine(out) + ATP + H2O = glycine betaine(in) + ADP + phosphate + H(+)
Direction not assertedBalancedTransportRhea 32783
L-ectoine(out) + ATP + H2O = L-ectoine(in) + ADP + phosphate + H(+)
Direction not assertedBalancedTransportRhea 32787
L-ectoine(in) = L-ectoine(out)
Direction not assertedBalancedTransportRhea 32791
L-cysteine(out) + ATP + H2O = L-cysteine(in) + ADP + phosphate + H(+)
Direction not assertedBalancedTransportRhea 32795
urea(in) = urea(out)
Direction not assertedBalancedTransportRhea 32799
urea(out) + ATP + H2O = urea(in) + ADP + phosphate + H(+)
Direction not assertedBalancedTransportRhea 32803
thiosulfate(in) = thiosulfate(out)

Direction not assertedBalancedTransportRhea 32807

benzoate(in) = benzoate(out)

Direction not assertedBalancedTransportRhea 32811

Hg(2+)(in) = Hg(2+)(out)

Direction not assertedBalancedTransportRhea 32815

chromate(in) = chromate(out)

Direction not assertedBalancedTransportRhea 32819

phosphate(in) = phosphate(out)

Left to rightBalancedTransportRhea 32823

methionine(out) + ATP + H2O = methionine(in) + ADP + phosphate + H(+)

Direction not assertedBalancedTransportRhea 32827

an R-cob(III)alamin(in) = an R-cob(III)alamin(out)

Direction not assertedBalance undeterminableTransportRhea 32831

4-(trimethylamino)butanoate(in) = 4-(trimethylamino)butanoate(out)

Direction not assertedBalancedTransportRhea 32835

a 1,2-diacyl-sn-glycerol + a 1,2-diacyl-sn-glycero-3-phosphocholine = a triacyl-sn-glycerol + a 1-acyl-sn-glycero-3-phosphocholine

Direction not assertedBalance undeterminableRhea 32843

a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + a 1,2-diacyl-sn-glycerol = a triacyl-sn-glycerol + a 1-acyl-sn-glycero-3-phosphoethanolamine

Direction not assertedBalance undeterminableRhea 32847

a 2-acylglycerol + a 1,2-diacyl-sn-glycero-3-phosphocholine = a 1-acyl-sn-glycero-3-phosphocholine + a 1,2-diacyl-sn-glycerol

Direction not assertedBalance undeterminableRhea 32851

a 2-acylglycerol + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine = a 1-acyl-sn-glycero-3-phosphoethanolamine + a 1,2-diacyl-sn-glycerol

Direction not assertedBalance undeterminableRhea 32855

a 1-acyl-sn-glycerol + a 1,2-diacyl-sn-glycero-3-phosphocholine = a 1-acyl-sn-glycero-3-phosphocholine + a 1,2-diacyl-sn-glycerol

Direction not assertedBalance undeterminableRhea 32859

a 1-acyl-sn-glycerol + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine = a 1-acyl-sn-glycero-3-phosphoethanolamine + a 1,2-diacyl-sn-glycerol

Direction not assertedBalance undeterminableRhea 32863

myo-inositol(out) = myo-inositol(in)

Direction not assertedBalancedTransportRhea 32867

a 2-acylglycerol + H2O = a carboxylate + glycerol + H(+)

Direction not assertedBalance undeterminableRhea 32871

a 1-acyl-sn-glycerol + H2O = glycerol + a fatty acid + H(+)

Direction not assertedBalance undeterminableRhea 32875

(1R,4R,5R)-5-hydroxycamphor + NAD(+) = (1R,4R)-bornane-2,5-dione + NADH + H(+)

Direction not assertedBalancedRhea 32879

(11R)-dihydroartemisinic aldehyde + NADP(+) = (+)-artemisinic aldehyde + NADPH + H(+)

Direction not assertedBalancedRhea 32883

all-trans-beta-carotene + O2 = 2 all-trans-retinal

Left to rightBalancedRhea 32887

(1S,5S)-alpha-pinene + NADH + O2 + H(+) = alpha-pinene oxide + NAD(+) + H2O

Direction not assertedBalancedRhea 32891

1,8-cineole + reduced [NADPH--hemoprotein reductase] + O2 = 2-exo-hydroxy-1,8-cineole + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 32895

1,8-cineole + reduced [flavodoxin] + O2 = 2-endo-hydroxy-1,8-cineole + oxidized [flavodoxin] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 32899

calciol + reduced [NADPH--hemoprotein reductase] + O2 = calcidiol + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Left to rightBalance undeterminableRhea 32903

a 1,2-diacyl-sn-glycero-3-phosphocholine + 2 H2O = sn-glycerol 3-phosphocholine + 2 a carboxylate + 2 H(+)

Direction not assertedBalance undeterminableRhea 32907

sn-glycerol 3-phosphocholine(out) = sn-glycerol 3-phosphocholine(in)

Direction not assertedBalancedTransportRhea 32911

sn-glycero-3-phospho-1D-myo-inositol(out) = sn-glycero-3-phospho-1D-myo-inositol(in)

Direction not assertedBalancedTransportRhea 32915

methyl (indol-3-yl)acetate + H2O = (indol-3-yl)acetate + methanol + H(+)

Direction not assertedBalancedRhea 32919

sn-glycero-3-phospho-(1'-sn-glycerol) + H2O = sn-glycerol 3-phosphate + glycerol + H(+)

Direction not assertedBalancedRhea 32923

a 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) + H2O = sn-glycerol 3-phosphate + a 1,2-diacyl-sn-glycerol + H(+)

Direction not assertedBalance undeterminableRhea 32927

a CDP-1,2-diacyl-sn-glycerol + a 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) = a cardiolipin + CMP + H(+)

Direction not assertedBalance undeterminableRhea 32931

a cardiolipin + H2O = 1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl-sn-glycero-3-phospho]-glycerol + a fatty acid + H(+)

Left to rightBalance undeterminableRhea 32935

CDP-choline + a 1,2-diacyl-sn-glycerol = a 1,2-diacyl-sn-glycero-3-phosphocholine + CMP + H(+)

Left to rightBalance undeterminableRhea 32939

CDP-ethanolamine + a 1,2-diacyl-sn-glycerol = a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + CMP + H(+)

Left to rightBalance undeterminableRhea 32943

a 2-acylglycerol + an acyl-CoA = a 1,2-diacyl-sn-glycerol + CoA

Left to rightBalance undeterminableRhea 32947

sucrose = trehalulose

Direction not assertedBalancedRhea 32951

a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,5-bisphosphate) + H2O = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + phosphate

Left to rightBalance undeterminableRhea 32955

L-isoleucine + NAD(+) + H2O = (S)-3-methyl-2-oxopentanoate + NH4(+) + NADH + H(+)

Direction not assertedBalancedRhea 32959

2-oxoglutaramate + H2O = 2-oxoglutarate + NH4(+)

Left to rightBalancedRhea 32963

a 1-acyl-sn-glycero-3-phosphoethanolamine + H2O = sn-glycero-3-phosphoethanolamine + a fatty acid + H(+)

Left to rightBalance undeterminableRhea 32967

a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + 2 H2O = sn-glycero-3-phosphoethanolamine + 2 a carboxylate + 2 H(+)

Direction not assertedBalance undeterminableRhea 32971

a 1,2-diacyl-sn-glycero-3-phospho-L-serine + 2 H2O = sn-glycero-3-phospho-L-serine + 2 a carboxylate + 2 H(+)

Direction not assertedBalance undeterminableRhea 32975

a 1-acyl-sn-glycero-3-phospho-L-serine + H2O = sn-glycero-3-phospho-L-serine + a fatty acid + H(+)

Left to rightBalance undeterminableRhea 32979

a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + 2 H2O = sn-glycero-3-phospho-1D-myo-inositol + 2 a carboxylate + 2 H(+)

Direction not assertedBalance undeterminableRhea 32983

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