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CompoundsSubstances with curated findings
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ProteinsTransporters and enzymes
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ReactionsRhea and Human-GEM, by subsystem
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Reference

Evidence

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Reach

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

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Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSourceClear

Reactions

5,201–5,250 of 18,558 reactions from Rhea

dihydrocarvone + NADPH + O2 + H(+) = 6-isopropenyl-3-methyloxepan-2-one + NADP(+) + H2O
Direction not assertedBalancedRhea 32583
(1R,4R)-dihydrocarvone + NADPH + O2 + H(+) = (3R,6R)-6-isopropenyl-3-methyloxepan-2-one + NADP(+) + H2O
Direction not assertedBalancedRhea 32587
(4R,7S)-7-isopropyl-4-methyloxepan-2-one + H2O = (3R,6S)-6-hydroxy-3,7-dimethyloctanoate + H(+)
Direction not assertedBalancedRhea 32591
7-isopropyl-4-methyloxepan-2-one + H2O = 6-hydroxy-3,7-dimethyloctanoate + H(+)
Direction not assertedBalancedRhea 32595
7-hydroxy-4-isopropenyl-7-methyloxepan-2-one = 3-isopropenyl-6-oxoheptanoate + H(+)
Direction not assertedBalancedRhea 32599
(6E)-8-hydroxygeraniol + NADP(+) = (6E)-8-oxogeraniol + NADPH + H(+)
Direction not assertedBalancedRhea 32603
(6E)-8-hydroxygeraniol + NADP(+) = (6E)-8-hydroxygeranial + NADPH + H(+)

Direction not assertedBalancedRhea 32607

(6E)-8-hydroxygeranial + NADP(+) = (6E)-8-oxogeranial + NADPH + H(+)

Direction not assertedBalancedRhea 32611

(6E)-8-oxogeraniol + NADP(+) = (6E)-8-oxogeranial + NADPH + H(+)

Direction not assertedBalancedRhea 32615

L-threo-7,8-dihydrobiopterin + NADP(+) = L-sepiapterin + NADPH + H(+)

Direction not assertedBalancedRhea 32619

L-threo-tetrahydrobiopterin + 2 NADP(+) = 6-pyruvoyl-5,6,7,8-tetrahydropterin + 2 NADPH + 2 H(+)

Direction not assertedBalancedRhea 32623

(6R)-L-erythro-5,6,7,8-tetrahydrobiopterin + 2 NADP(+) = 6-pyruvoyl-5,6,7,8-tetrahydropterin + 2 NADPH + 2 H(+)

Right to leftBalancedRhea 32627

erythromycin D + NADPH + O2 + H(+) = erythromycin C + NADP(+) + H2O

Direction not assertedBalancedRhea 32631

linalool + 2 reduced [NADPH--hemoprotein reductase] + 2 O2 = (6E)-8-oxolinalool + 2 oxidized [NADPH--hemoprotein reductase] + 3 H2O + 2 H(+)

Direction not assertedBalance undeterminableRhea 32635

(6E)-8-hydroxylinalool + reduced [NADPH--hemoprotein reductase] + O2 = (6E)-8-oxolinalool + oxidized [NADPH--hemoprotein reductase] + 2 H2O + H(+)

Direction not assertedBalance undeterminableRhea 32639

lupanine + 2 Fe(III)-[cytochrome c] + H2O = 17-hydroxylupanine + 2 Fe(II)-[cytochrome c] + 2 H(+)

Direction not assertedBalance undeterminableRhea 32643

erythromycin C + S-adenosyl-L-methionine = erythromycin A + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 32647

erythromycin D + S-adenosyl-L-methionine = erythromycin B + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 32651

eugenol + a carboxylate + NADP(+) = a coniferyl ester + NADPH

Direction not assertedBalance undeterminableRhea 32655

(6E)-8-hydroxygeraniol + 2 NADP(+) = (6E)-8-oxogeranial + 2 NADPH + 2 H(+)

Direction not assertedBalancedRhea 32659

5-guanidino-2-oxopentanoate + S-adenosyl-L-methionine = (3R)-5-guanidino-3-methyl-2-oxopentanoate + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 32663

methanethiol + coenzyme M = methyl-coenzyme M + hydrogen sulfide + H(+)

Direction not assertedBalancedRhea 32667

UDP-N-acetyl-alpha-D-glucosamine + ATP = UDP-N-acetyl-alpha-D-glucosamine 3'-phosphate + ADP + H(+)

Direction not assertedBalancedRhea 32671

alpha,alpha-trehalose + H2O = alpha-D-glucose + beta-D-glucose

Direction not assertedBalancedRhea 32675

(2E)-geranyl diphosphate + H2O = (2E)-geraniol + diphosphate

Direction not assertedBalancedRhea 32679

5-hydroxymethylfurfural + 3 O2 + 2 H2O = 2,5-dicarboxyfuran + 3 H2O2 + 2 H(+)

Direction not assertedBalancedRhea 32683

(2E)-geranyl diphosphate = tricyclene + diphosphate

Direction not assertedBalancedRhea 32687

(2E)-geranyl diphosphate = (E)-beta-ocimene + diphosphate

Direction not assertedBalancedRhea 32691

(2E)-geranyl diphosphate = (-)-car-3-ene + diphosphate

Direction not assertedBalancedRhea 32695

(2E,6E)-farnesyl diphosphate = beta-sesquiphellandrene + diphosphate

Direction not assertedBalancedRhea 32699

(2E,6E,10E)-geranylgeranyl diphosphate + H2O = 8-hydroxycopalyl diphosphate

Direction not assertedBalancedRhea 32703

(2E)-geranyl diphosphate = (2R,4S)-bornyl diphosphate

Direction not assertedBalancedRhea 32707

a (3R)-3-hydroxyacyl-CoA + NAD(+) = a 3-oxoacyl-CoA + NADH + H(+)

Left to rightBalance undeterminableRhea 32711

(2R,3S)-3-methylmalate + NAD(+) = 2-oxobutanoate + CO2 + NADH

Direction not assertedBalancedRhea 32715

L-dihomomethionine + 2 reduced [NADPH--hemoprotein reductase] + 2 O2 = (E)-5-(methylsulfanyl)pentanal oxime + 2 oxidized [NADPH--hemoprotein reductase] + CO2 + 3 H2O + 2 H(+)

Direction not assertedBalance undeterminableRhea 32719

L-trihomomethionine + 2 reduced [NADPH--hemoprotein reductase] + 2 O2 = (E)-6-(methylsulfanyl)hexanal oxime + 2 oxidized [NADPH--hemoprotein reductase] + CO2 + 3 H2O + 2 H(+)

Direction not assertedBalance undeterminableRhea 32723

a very-long-chain acyl-CoA + malonyl-CoA + H(+) = a very-long-chain 3-oxoacyl-CoA + CO2 + CoA

Left to rightBalance undeterminableRhea 32727

a diacylglycerol + H2O = a monoacylglycerol + a fatty acid + H(+)

Left to rightBalance undeterminableRhea 32731

a 1,2-diacyl-sn-glycero-3-phospho-N-methylethanolamine + S-adenosyl-L-methionine = a 1,2-diacyl-sn-glycero-3-phospho-N,N-dimethylethanolamine + S-adenosyl-L-homocysteine + H(+)

Left to rightBalance undeterminableRhea 32735

a 1,2-diacyl-sn-glycero-3-phospho-N,N-dimethylethanolamine + S-adenosyl-L-methionine = a 1,2-diacyl-sn-glycero-3-phosphocholine + S-adenosyl-L-homocysteine + H(+)

Left to rightBalance undeterminableRhea 32739

O-acetyl-L-serine + L-homocysteine = L,L-cystathionine + acetate + H(+)

Direction not assertedBalancedRhea 32743

ethanolamine(in) = ethanolamine(out)

Direction not assertedBalancedTransportRhea 32747

choline(out) = choline(in)

Direction not assertedBalancedTransportRhea 32751

(2S)-naringenin + 2-oxoglutarate + O2 = apigenin + succinate + CO2 + H2O + H(+)

Direction not assertedBalancedRhea 32755

L-lysine = (3R)-3-methyl-D-ornithine

Direction not assertedBalancedRhea 32759

(3R)-3-methyl-D-ornithine + L-lysine + ATP = (3R)-3-methyl-D-ornithyl-N(6)-L-lysine + ADP + phosphate + H(+)

Direction not assertedBalancedRhea 32763

cytidine(4) in tRNA(Pro) + S-adenosyl-L-methionine = 2'-O-methylcytidine(4) in tRNA(Pro) + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 32767

2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate = 2,6-dioxo-6-phenylhexa-3-enoate

Direction not assertedBalancedRhea 32771

(2-aminoethyl)phosphonate(out) + ATP + H2O = (2-aminoethyl)phosphonate(in) + ADP + phosphate + H(+)

Direction not assertedBalancedTransportRhea 32775

Co(2+)(out) + ATP + H2O = Co(2+)(in) + ADP + phosphate + H(+)

Direction not assertedBalancedTransportRhea 32779

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