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CompoundsSubstances with curated findings
OutcomesMeasured endpoints
ProteinsTransporters and enzymes
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ReactionsRhea and Human-GEM, by subsystem
ReachWhat a compound can become

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PathwaysReactions grouped under one name
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Reference

Evidence

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Reach

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

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Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSourceClear

Reactions

5,001–5,050 of 18,558 reactions from Rhea

a 4'-hydroxyflavanone + S-adenosyl-L-methionine = a 4'-methoxyflavanone + S-adenosyl-L-homocysteine + H(+)
Direction not assertedBalance undeterminableRhea 31743
3-oxo-5,6-dehydrosuberyl-CoA semialdehyde + NADP(+) + H2O = 3-oxo-5,6-didehydrosuberyl-CoA + NADPH + 2 H(+)
Direction not assertedBalancedRhea 31747
chlorophyllide a + 2 oxidized [2Fe-2S]-[ferredoxin] + H2O = 7(1)-hydroxychlorophyllide a + 2 reduced [2Fe-2S]-[ferredoxin] + 2 H(+)
Direction not assertedBalance undeterminableRhea 31751
2-oxepin-2(3H)-ylideneacetyl-CoA + H2O = 3-oxo-5,6-dehydrosuberyl-CoA semialdehyde
Direction not assertedBalancedRhea 31755
dTDP-3-amino-3,4,6-trideoxy-alpha-D-glucose + 2 S-adenosyl-L-methionine = dTDP-alpha-D-desosamine + 2 S-adenosyl-L-homocysteine + 2 H(+)
Direction not assertedBalancedRhea 31759
a 2-oxocarboxylate + L-methionine = 4-methylsulfanyl-2-oxobutanoate + an L-alpha-amino acid
Direction not asserted

Balance undeterminable

Rhea 31763

UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine + 2-oxoglutarate = UDP-2-acetamido-2,6-dideoxy-beta-L-arabino-hex-4-ulose + L-glutamate

Direction not assertedBalancedRhea 31767

an all-trans-retinyl ester + H2O = 11-cis-retinol + a fatty acid + H(+)

Direction not assertedBalance undeterminableRhea 31771

all-trans-retinyl hexadecanoate + H2O = 11-cis-retinol + hexadecanoate + H(+)

Direction not assertedBalancedRhea 31775

an all-trans-retinyl ester + H2O = 13-cis-retinol + a fatty acid + H(+)

Direction not assertedBalance undeterminableRhea 31779

tuberculosinyl diphosphate + H2O = tuberculosinol + diphosphate

Direction not assertedBalancedRhea 31783

tuberculosinyl diphosphate + H2O = (13R)-edaxadiene + diphosphate

Direction not assertedBalancedRhea 31787

tuberculosinyl diphosphate + H2O = (13S)-edaxadiene + diphosphate

Direction not assertedBalancedRhea 31791

(+)-(E)-beta-caryophyllene + H2O = (+)-caryolan-1-ol

Direction not assertedBalancedRhea 31795

4-amino-5-aminomethyl-2-methylpyrimidine + H2O = 4-amino-5-hydroxymethyl-2-methylpyrimidine + NH4(+)

Direction not assertedBalancedRhea 31799

UDP-2,4-diacetamido-2,4,6-trideoxy-beta-L-altrose + H2O = 2,4-diacetamido-2,4,6-trideoxy-beta-L-altrose + UDP + H(+)

Direction not assertedBalancedRhea 31803

(2E,6E)-farnesyl diphosphate = alpha-guaiene + diphosphate

Direction not assertedBalancedRhea 31807

(2E,6E)-farnesyl diphosphate = viridiflorene + diphosphate

Direction not assertedBalancedRhea 31811

(2E,6E)-farnesyl diphosphate = (+)-(E)-beta-caryophyllene + diphosphate

Direction not assertedBalancedRhea 31815

(2E,6E)-farnesyl diphosphate = 5-epi-alpha-selinene + diphosphate

Direction not assertedBalancedRhea 31819

(2E,6E)-farnesyl diphosphate + H2O = cubebol + diphosphate

Direction not assertedBalancedRhea 31823

(2E,6E)-farnesyl diphosphate = (+)-gamma-cadinene + diphosphate

Direction not assertedBalancedRhea 31827

(2E,6E)-farnesyl diphosphate = delta-guaiene + diphosphate

Direction not assertedBalancedRhea 31831

dTDP-4-dehydro-6-deoxy-alpha-D-glucose = dTDP-3-dehydro-6-deoxy-alpha-D-galactose

Direction not assertedBalancedRhea 31835

dTDP-4-dehydro-6-deoxy-alpha-D-glucose = dTDP-3-dehydro-6-deoxy-alpha-D-glucose

Direction not assertedBalancedRhea 31839

2-(1,2-epoxy-1,2-dihydrophenyl)acetyl-CoA = 2-oxepin-2(3H)-ylideneacetyl-CoA

Direction not assertedBalancedRhea 31843

(S)-2,3-epoxysqualene = shionone

Direction not assertedBalancedRhea 31847

(S)-2,3-epoxysqualene = parkeol

Direction not assertedBalancedRhea 31851

(S)-2,3-epoxysqualene = achilleol B

Direction not assertedBalancedRhea 31855

(S)-2,3-epoxysqualene = glutinol

Direction not assertedBalancedRhea 31859

(S)-2,3-epoxysqualene = friedelin

Direction not assertedBalancedRhea 31863

(S)-2,3-epoxysqualene = baccharis oxide

Direction not assertedBalancedRhea 31867

(S)-2,3-epoxysqualene = alpha-seco-amyrin

Direction not assertedBalancedRhea 31871

(S)-2,3-epoxysqualene = marneral

Direction not assertedBalancedRhea 31875

(S)-2,3-epoxysqualene = beta-seco-amyrin

Direction not assertedBalancedRhea 31879

(S)-2,3-epoxysqualene = delta-amyrin

Direction not assertedBalancedRhea 31883

(S)-2,3-epoxysqualene = tirucalla-7,24-dien-3beta-ol

Direction not assertedBalancedRhea 31887

2-hydroxy-1-phenyl-1-propanone + NADP(+) = 1-phenyl-1,2-propanedione + NADPH + H(+)

Direction not assertedBalancedRhea 31891

(2E,6E)-farnesyl diphosphate = alpha-humulene + diphosphate

Direction not assertedBalancedRhea 31895

indole + reduced [NADPH--hemoprotein reductase] + O2 = indolin-2-one + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 31899

(S)-norcoclaurine + S-adenosyl-L-methionine = (S)-coclaurine + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 31907

beta-D-fructose 1,6-bisphosphate + methylglyoxal = 1-deoxy-D-threo-hexo-2,5-diulose 6-phosphate + D-glyceraldehyde 3-phosphate

Direction not assertedBalancedRhea 31911

D-maltose + ATP = alpha-maltose 1-phosphate + ADP + H(+)

Direction not assertedBalancedRhea 31915

indolin-2-one + reduced [NADPH--hemoprotein reductase] + O2 = 3-hydroxyindolin-2-one + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 31919

3-hydroxyindolin-2-one + reduced [NADPH--hemoprotein reductase] + O2 = 2-hydroxy-2H-1,4-benzoxazin-3(4H)-one + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 31927

2-hydroxy-2H-1,4-benzoxazin-3(4H)-one + reduced [NADPH--hemoprotein reductase] + O2 = DIBOA + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 31939

cholest-4-en-3-one + 2 reduced [2Fe-2S]-[ferredoxin] + O2 + 2 H(+) = (25S)-3-oxocholest-4-en-26-ol + 2 oxidized [2Fe-2S]-[ferredoxin] + H2O

Direction not assertedBalance undeterminableRhea 31943

ent-isokaurene + reduced [NADPH--hemoprotein reductase] + O2 = ent-isokauren-2beta-ol + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 31947

9beta-pimara-7,15-diene + 3 reduced [NADPH--hemoprotein reductase] + 3 O2 = 9beta-pimara-7,15-dien-19-oate + 3 oxidized [NADPH--hemoprotein reductase] + 4 H2O + 4 H(+)

Direction not assertedBalance undeterminableRhea 31951

9beta-pimara-7,15-diene + reduced [NADPH--hemoprotein reductase] + O2 = 9beta-pimara-7,15-dien-19-ol + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 31955

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