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CompoundsSubstances with curated findings
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ProteinsTransporters and enzymes
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ReactionsRhea and Human-GEM, by subsystem
ReachWhat a compound can become

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Reference

Evidence

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Reach

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

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Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSourceClear

Reactions

4,951–5,000 of 18,558 reactions from Rhea

(2S)-naringenin + S-adenosyl-L-methionine = (2S)-sakuranetin + S-adenosyl-L-homocysteine + H(+)
Direction not assertedBalancedRhea 31539
all-trans-zeaxanthin + 2 UDP-alpha-D-glucose = zeaxanthin bis(beta-D-glucoside) + 2 UDP + 2 H(+)
Direction not assertedBalancedRhea 31543
2 (2E,6E)-farnesyl diphosphate = 15-cis-4,4'-diapophytoene + 2 diphosphate
Direction not assertedBalancedRhea 31547
presqualene diphosphate = 15-cis-4,4'-diapophytoene + diphosphate
Direction not assertedBalancedRhea 31551
(5S)-5-amino-3-oxohexanoate + acetyl-CoA = (3S)-3-aminobutanoyl-CoA + acetoacetate
Direction not assertedBalancedRhea 31555
L-galactose + NAD(+) = L-galactono-1,4-lactone + NADH + H(+)
Direction not assertedBalancedRhea 31559
leukotriene C4 + H2O = leukotriene D4 + L-glutamate

Left to rightBalancedRhea 31563

bisphenol A + NADH + O2 + H(+) = 2,2-bis(4-hydroxyphenyl)-1-propanol + NAD(+) + H2O

Direction not assertedBalancedRhea 31567

1-hydroxy-2-naphthoate + NADPH + O2 + 2 H(+) = naphthalene-1,2-diol + CO2 + NADP(+) + H2O

Direction not assertedBalancedRhea 31571

8-oxo-dGTP + H2O = 8-oxo-dGMP + diphosphate + H(+)

Left to rightBalancedRhea 31575

(8R,9Z,12Z)-8-hydroperoxyoctadeca-9,12-dienoate = (5S,8R,9Z,12Z)-5,8-dihydroxyoctadeca-9,12-dienoate

Direction not assertedBalancedRhea 31579

2-oxo-dATP + H2O = 2-oxo-dAMP + diphosphate + H(+)

Left to rightBalancedRhea 31583

uracil + FMNH2 + NADH + O2 = (Z)-3-ureidoacrylate + FMN + NAD(+) + H2O + H(+)

Direction not assertedBalancedRhea 31587

(Z)-2-methylureidoacrylate + H2O = (Z)-2-methylaminoacrylate + carbamate + H(+)

Direction not assertedBalancedRhea 31595

thymine + FMNH2 + NADH + O2 = (Z)-2-methylureidoacrylate + FMN + NAD(+) + H2O + H(+)

Direction not assertedBalancedRhea 31599

(Z)-3-ureidoacrylate + H2O = (Z)-3-aminoacrylate + carbamate + H(+)

Direction not assertedBalancedRhea 31603

rhodopin = all-trans-lycopene + H2O

Direction not assertedBalancedRhea 31607

1,1'-dihydroxy-1,1',2,2'-tetrahydrolycopene = rhodopin + H2O

Direction not assertedBalancedRhea 31611

dTDP-3-amino-3,6-dideoxy-alpha-D-galactopyranose + 2 S-adenosyl-L-methionine = dTDP-D-ravidosamine + 2 S-adenosyl-L-homocysteine + 2 H(+)

Direction not assertedBalancedRhea 31615

dTDP-3-amino-3,6-dideoxy-alpha-D-galactopyranose + 2-oxoglutarate = dTDP-3-dehydro-6-deoxy-alpha-D-galactose + L-glutamate

Direction not assertedBalancedRhea 31619

L-olivosyl-oleandolide + S-adenosyl-L-methionine = L-oleandrosyl-oleandolide + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 31623

10-deoxymethynolide + dTDP-alpha-D-desosamine = 10-deoxymethymycin + dTDP + H(+)

Direction not assertedBalancedRhea 31627

2,4-diacetamido-2,4,6-trideoxy-beta-L-altrose + phosphoenolpyruvate + H2O = pseudaminate + phosphate

Direction not assertedBalancedRhea 31631

beta-D-Delta(4)-GlcA-(1->4)-beta-D-Glc-(1->4)-alpha-L-Rha-(1->3)-D-Glc + H2O = beta-D-Glc-(1->4)-alpha-L-Rha-(1->3)-D-Glc + 5-dehydro-4-deoxy-D-glucuronate

Direction not assertedBalancedRhea 31635

mycinamicin III + S-adenosyl-L-methionine = mycinamicin IV + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 31639

mycinamicin VI + S-adenosyl-L-methionine = mycinamicin III + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 31643

beta-D-4-deoxy-Delta(4)-GlcpA-(1->3)-beta-D-GalpNAc6S + H2O = N-acetyl-beta-D-galactosamine 6-sulfate + 5-dehydro-4-deoxy-D-glucuronate

Direction not assertedBalancedRhea 31647

beta-D-4-deoxy-Delta(4)-GlcpA-(1->3)-beta-D-GalpNAc + H2O = 5-dehydro-4-deoxy-D-glucuronate + N-acetyl-beta-D-galactosamine

Direction not assertedBalancedRhea 31651

4-deoxy-Delta(4)-beta-D-GlcpA2S-(1->3)-beta-D-GalpNAc + H2O = 5-dehydro-4-deoxy-2-O-sulfo-D-glucuronate + N-acetyl-beta-D-galactosamine

Direction not assertedBalancedRhea 31655

beta-D-4-deoxy-Delta(4)-GlcpA-(1->3)-beta-D-GlcpNAc + H2O = 5-dehydro-4-deoxy-D-glucuronate + N-acetyl-beta-D-galactosamine

Direction not assertedBalancedRhea 31659

UDP-N-acetylbacillosamine + 2-oxoglutarate = UDP-2-acetamido-2,6-dideoxy-alpha-D-xylo-hex-4-ulose + L-glutamate

Direction not assertedBalancedRhea 31663

dTDP-3-amino-3,6-dideoxy-alpha-D-glucose + 2-oxoglutarate = dTDP-3-dehydro-6-deoxy-alpha-D-glucose + L-glutamate

Direction not assertedBalancedRhea 31667

dTDP-3-amino-3,6-dideoxy-alpha-D-glucose + 2 S-adenosyl-L-methionine = dTDP-alpha-D-mycaminose + 2 S-adenosyl-L-homocysteine + 2 H(+)

Direction not assertedBalancedRhea 31671

raucaffrinoline + NADP(+) = perakine + NADPH + H(+)

Direction not assertedBalancedRhea 31675

prosolanapyrone II + O2 = prosolanapyrone III + H2O2

Direction not assertedBalancedRhea 31679

prosolanapyrone III = (-)-solanapyrone A

Direction not assertedBalancedRhea 31683

(9Z,12Z,15Z)-octadecatrienoate + O2 = (9R,10E,12Z,15Z)-9-hydroperoxyoctadeca-10,12,15-trienoate

Direction not assertedBalancedRhea 31687

(9Z,12Z)-octadecadienoate + O2 = (9R)-hydroperoxy-(10E,12Z)-octadecadienoate

Direction not assertedBalancedRhea 31691

(9Z,12Z)-octadecadienoate + O2 = (8E,10R,12Z)-10-hydroperoxyoctadeca-8,12-dienoate

Direction not assertedBalancedRhea 31695

pentalenene + 4 reduced [2Fe-2S]-[ferredoxin] + 2 O2 + 4 H(+) = pentalen-13-al + 4 oxidized [2Fe-2S]-[ferredoxin] + 3 H2O

Direction not assertedBalance undeterminableRhea 31699

pentalenene + 2 reduced [2Fe-2S]-[ferredoxin] + O2 + 2 H(+) = pentalen-13-ol + 2 oxidized [2Fe-2S]-[ferredoxin] + H2O

Direction not assertedBalance undeterminableRhea 31703

pentalen-13-ol + 2 reduced [2Fe-2S]-[ferredoxin] + O2 + 2 H(+) = pentalen-13-al + 2 oxidized [2Fe-2S]-[ferredoxin] + 2 H2O

Direction not assertedBalance undeterminableRhea 31707

beta-amyrin + 2 reduced [NADPH--hemoprotein reductase] + 2 O2 = 11-oxo-beta-amyrin + 2 oxidized [NADPH--hemoprotein reductase] + 3 H2O + 2 H(+)

Direction not assertedBalance undeterminableRhea 31711

beta-amyrin + reduced [NADPH--hemoprotein reductase] + O2 = 11alpha-hydroxy-beta-amyrin + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 31715

11alpha-hydroxy-beta-amyrin + reduced [NADPH--hemoprotein reductase] + O2 = 11-oxo-beta-amyrin + oxidized [NADPH--hemoprotein reductase] + 2 H2O + H(+)

Direction not assertedBalance undeterminableRhea 31719

(2S)-liquiritigenin + reduced [NADPH--hemoprotein reductase] + O2 = (2R,3S)-2,4',7-trihydroxyisoflavanone + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 31723

styrene + FADH2 + O2 = (S)-styrene oxide + FAD + H2O + H(+)

Direction not assertedBalancedRhea 31727

3-hydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione + FMNH2 + O2 = 3,4-dihydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione + FMN + H2O + H(+)

Direction not assertedBalancedRhea 31731

3-oxocholan-24-oyl-CoA + NAD(+) = 3-oxochol-4-en-24-oyl-CoA + NADH + H(+)

Direction not assertedBalancedRhea 31735

a 4'-hydroxyisoflavone + S-adenosyl-L-methionine = a 4'-methoxyisoflavone + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalance undeterminableRhea 31739

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