Reactions

CYP3A4

185 reactions

• testosterone + reduced [NADPH--hemoprotein reductase] + dioxygen → 6beta,17beta-dihydroxyandrost-4-en-3-one + oxidized [NADPH--hemoprotein reductase] + water + hydron

  → Balance undeterminable

• estrone + reduced [NADPH--hemoprotein reductase] + dioxygen → 16alpha-hydroxyestrone + oxidized [NADPH--hemoprotein reductase] + water + hydron

  → Balance undeterminable

• estrone + reduced [NADPH--hemoprotein reductase] + dioxygen → 2-hydroxyestrone + oxidized [NADPH--hemoprotein reductase] + water + hydron

  → Balance undeterminable

• 17beta-estradiol + reduced [NADPH--hemoprotein reductase] + dioxygen → 2-hydroxy-17beta-estradiol + oxidized [NADPH--hemoprotein reductase] + water + hydron

  → Balance undeterminable

• progesterone + reduced [NADPH--hemoprotein reductase] + dioxygen → 6beta-hydroxyprogesterone + oxidized [NADPH--hemoprotein reductase] + water + hydron

  → Balance undeterminable

• androst-4-ene-3,17-dione + reduced [NADPH--hemoprotein reductase] + dioxygen → 6beta-hydroxyandrost-4-ene-3,17-dione + oxidized [NADPH--hemoprotein reductase] + water + hydron

  → Balance undeterminable

• progesterone + reduced [NADPH--hemoprotein reductase] + dioxygen → 16alpha-hydroxyprogesterone + oxidized [NADPH--hemoprotein reductase] + water + hydron

  → Balance undeterminable

• 17beta-estradiol + reduced [NADPH--hemoprotein reductase] + dioxygen → 4-hydroxy-17beta-estradiol + oxidized [NADPH--hemoprotein reductase] + water + hydron

  → Balance undeterminable

• estrone + reduced [NADPH--hemoprotein reductase] + dioxygen → 4-hydroxyestrone + oxidized [NADPH--hemoprotein reductase] + water + hydron

  → Balance undeterminable

• 17beta-estradiol + reduced [NADPH--hemoprotein reductase] + dioxygen → 16alpha,17beta-estriol + oxidized [NADPH--hemoprotein reductase] + water + hydron

  → Balance undeterminable

• 17beta-estradiol + reduced [NADPH--hemoprotein reductase] + dioxygen → 16beta,17beta-estriol + oxidized [NADPH--hemoprotein reductase] + water + hydron

  → Balance undeterminable

• CHEBI:80788 + reduced [NADPH--hemoprotein reductase] + dioxygen → CHEBI:90956 + oxidized [NADPH--hemoprotein reductase] + water + hydron

  → Balance undeterminable

• (5Z,8Z,11Z,14Z)-eicosatetraenoate + reduced [NADPH--hemoprotein reductase] + dioxygen → (14S,15R)-epoxy-(5Z,8Z,11Z)-eicosatrienoate + oxidized [NADPH--hemoprotein reductase] + water + hydron

  → Balance undeterminable

• (5Z,8Z,11Z,14Z)-eicosatetraenoate + reduced [NADPH--hemoprotein reductase] + dioxygen → (14R,15S)-epoxy-(5Z,8Z,11Z)-eicosatrienoate + oxidized [NADPH--hemoprotein reductase] + water + hydron

  → Balance undeterminable

• cholesterol + reduced [NADPH--hemoprotein reductase] + dioxygen → 25-hydroxycholesterol + oxidized [NADPH--hemoprotein reductase] + water + hydron

  → Balance undeterminable

• cholesterol + reduced [NADPH--hemoprotein reductase] + dioxygen → 26-hydroxycholesterol + oxidized [NADPH--hemoprotein reductase] + water + hydron

  → Balance undeterminable

• all-trans-retinoate + reduced [NADPH--hemoprotein reductase] + dioxygen → all-trans-4-hydroxyretinoate + oxidized [NADPH--hemoprotein reductase] + water + hydron

  → Balance undeterminable

• all-cis-docosa-4,7,10,13,16,19-hexaenoic acid + reduced [NADPH--hemoprotein reductase] + dioxygen → (19R,20S)-epoxy-(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate + oxidized [NADPH--hemoprotein reductase] + water + hydron

  → Balance undeterminable

• all-cis-docosa-4,7,10,13,16,19-hexaenoic acid + reduced [NADPH--hemoprotein reductase] + dioxygen → (19S,20R)-epoxy-(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate + oxidized [NADPH--hemoprotein reductase] + water + hydron

  → Balance undeterminable

• (9Z,12Z)-octadecadienoate + reduced [NADPH--hemoprotein reductase] + dioxygen → 11-hydroxy-(9Z,12Z)-octadecadienoate + oxidized [NADPH--hemoprotein reductase] + water + hydron

  → Balance undeterminable

• (5Z,8Z,11Z,14Z)-eicosatetraenoate + reduced [NADPH--hemoprotein reductase] + dioxygen → 7-hydroxy-(5Z,8Z,11Z,14Z)-eicosatetraenoate + oxidized [NADPH--hemoprotein reductase] + water + hydron

  → Balance undeterminable

• (5Z,8Z,11Z,14Z)-eicosatetraenoate + reduced [NADPH--hemoprotein reductase] + dioxygen → 13-hydroxy-(5Z,8Z,11Z,14Z)-eicosatetraenoate + oxidized [NADPH--hemoprotein reductase] + water + hydron

  → Balance undeterminable

• (5Z,8Z,11Z,14Z)-eicosatetraenoate + reduced [NADPH--hemoprotein reductase] + dioxygen → 10-hydroxy-(5Z,8Z,11Z,14Z)-eicosatetraenoate + oxidized [NADPH--hemoprotein reductase] + water + hydron

  → Balance undeterminable

• N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-ethanolamine + reduced [NADPH--hemoprotein reductase] + dioxygen → CHEBI:136989 + oxidized [NADPH--hemoprotein reductase] + water + hydron

  → Balance undeterminable

• N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-ethanolamine + reduced [NADPH--hemoprotein reductase] + dioxygen → CHEBI:136990 + oxidized [NADPH--hemoprotein reductase] + water + hydron

  → Balance undeterminable

• N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-ethanolamine + reduced [NADPH--hemoprotein reductase] + dioxygen → CHEBI:136991 + oxidized [NADPH--hemoprotein reductase] + water + hydron

  → Balance undeterminable

• 17beta-hydroxy-5alpha-androstan-3-one + reduced [NADPH--hemoprotein reductase] + dioxygen → CHEBI:137031 + oxidized [NADPH--hemoprotein reductase] + water + hydron

  → Balance undeterminable

• 17beta-hydroxy-5alpha-androstan-3-one + reduced [NADPH--hemoprotein reductase] + dioxygen → CHEBI:137037 + oxidized [NADPH--hemoprotein reductase] + water + hydron

  → Balance undeterminable

• testosterone + reduced [NADPH--hemoprotein reductase] + dioxygen → 1beta-hydroxytestosterone + oxidized [NADPH--hemoprotein reductase] + water + hydron

  → Balance undeterminable

• testosterone + reduced [NADPH--hemoprotein reductase] + dioxygen → 2beta-hydroxytestosterone + oxidized [NADPH--hemoprotein reductase] + water + hydron

  → Balance undeterminable

• testosterone + reduced [NADPH--hemoprotein reductase] + dioxygen → 11beta,17beta-dihydroxyandrost-4-ene-3-one + oxidized [NADPH--hemoprotein reductase] + water + hydron

  → Balance undeterminable

• cortisol + reduced [NADPH--hemoprotein reductase] + dioxygen → CHEBI:139271 + oxidized [NADPH--hemoprotein reductase] + water + hydron

  → Balance undeterminable

• cortisone + reduced [NADPH--hemoprotein reductase] + dioxygen → CHEBI:139269 + oxidized [NADPH--hemoprotein reductase] + water + hydron

  → Balance undeterminable

• CHEBI:16664 + reduced [NADPH--hemoprotein reductase] + dioxygen → CHEBI:16959 + oxidized [NADPH--hemoprotein reductase] + water + hydron

  → Balance undeterminable

• CHEBI:77092 + reduced [NADPH--hemoprotein reductase] + dioxygen → CHEBI:35812 + oxidized [NADPH--hemoprotein reductase] + water + hydron

  → Balance undeterminable

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