Reactions
CYP17A1
29 reactions
- MAM00592c + proton + NADPH(4-) + dioxygen → (20R)-17alpha,20-dihydroxycholesterol + water + NADP(3-)
→ Balanced · EC 1.14.14.19
- proton + NADPH(4-) + dioxygen + pregnenolone → 17alpha-hydroxypregnenolone + water + NADP(3-)
→ Balanced · EC 1.14.14.19
- proton + NADPH(4-) + dioxygen + pregnenolone → 17alpha-hydroxypregnenolone + water + NADP(3-)
→ Balanced · EC 1.14.14.19
- 17alpha-hydroxypregnenolone + 2 proton + 2 NADPH(4-) + dioxygen → acetaldehyde + 3beta-hydroxyandrost-5-en-17-one + 2 water + 2 NADP(3-)
→ Balanced · EC 1.14.14.32
- 17alpha-hydroxypregnenolone + NADPH(4-) + dioxygen → acetate + 3beta-hydroxyandrost-5-en-17-one + water + NADP(3-)
→ Balanced · EC 1.14.99.-
- 17alpha-hydroxypregnenolone + NADPH(4-) + dioxygen ⇌ acetate + 3beta-hydroxyandrost-5-en-17-one + water + NADP(3-)
⇌ Balanced · EC 1.14.99.-
- proton + NADPH(4-) + dioxygen + progesterone → 17alpha-hydroxyprogesterone + water + NADP(3-)
→ Balanced · EC 1.14.14.19
- 17alpha-hydroxyprogesterone + NADPH(4-) + dioxygen → androst-4-ene-3,17-dione + acetate + water + NADP(3-)
→ Balanced · EC 1.14.99.-
- 17alpha-hydroxyprogesterone + NADPH(4-) + dioxygen ⇌ androst-4-ene-3,17-dione + acetate + water + NADP(3-)
⇌ Balanced · EC 1.14.99.-
- MAM00603c + water + NADP(3-) → 11beta-hydroxyprogesterone + proton + NADPH(4-) + dioxygen
→ Balanced · EC 1.14.14.19
- cortisol + proton + 2 NADPH(4-) + dioxygen → 11beta-hydroxyandrost-4-ene-3,17-dione + acetate + 2 water + 2 NADP(3-)
→ Balanced · EC 1.14.15.4, 1.14.14.19
- cortisol + proton + 2 NADPH(4-) + dioxygen → 11beta-hydroxyandrost-4-ene-3,17-dione + acetate + 2 water + 2 NADP(3-)
→ Balanced · EC 1.14.15.4, 1.14.99.-
- cortisol + proton + 2 NADPH(4-) + dioxygen → 11beta-hydroxyandrost-4-ene-3,17-dione + acetate + 2 water + 2 NADP(3-)
→ Balanced · EC 1.14.15.4, 1.14.99.-
- 17alpha-hydroxyprogesterone + NADPH(4-) + dioxygen → androst-4-ene-3,17-dione + acetate + water + NADP(3-)
→ Balanced · EC 2.4.1.17
- 17alpha-hydroxypregnenolone + NADPH(4-) + dioxygen → acetate + 3beta-hydroxyandrost-5-en-17-one + water + NADP(3-)
→ Balanced · EC 2.4.1.17
- cortisol + proton + NADPH(4-) → 11beta-hydroxyandrost-4-ene-3,17-dione + acetaldehyde + water + NADP(3-)
→ Balanced · EC 2.3.1.65
- 17alpha-hydroxypregnenolone + proton + NADPH(4-) + 0.5 dioxygen → acetaldehyde + 3beta-hydroxyandrost-5-en-17-one + water + NADP(3-)
→ Balanced · EC 1.14.14.19
- proton + NADPH(4-) + dioxygen + progesterone → 17alpha-hydroxyprogesterone + water + NADP(3-)
→ Balanced · EC 1.14.14.19
- 17alpha-hydroxyprogesterone + proton + NADPH(4-) + 0.5 dioxygen → androst-4-ene-3,17-dione + acetaldehyde + water + NADP(3-)
→ Balanced · EC 1.14.14.19
- 17alpha-hydroxyprogesterone + reduced [NADPH--hemoprotein reductase] + dioxygen → androst-4-ene-3,17-dione + acetate + oxidized [NADPH--hemoprotein reductase] + water + 2 hydron
→ Balance undeterminable
- progesterone + reduced [NADPH--hemoprotein reductase] + dioxygen → 17alpha-hydroxyprogesterone + oxidized [NADPH--hemoprotein reductase] + water + hydron
→ Balance undeterminable
- 3beta-hydroxyandrost-5-en-17-one + reduced [NADPH--hemoprotein reductase] + dioxygen → 3beta,16alpha-dihydroxy-androst-5-en-17-one + oxidized [NADPH--hemoprotein reductase] + water + hydron
→ Balance undeterminable
- pregnenolone + reduced [NADPH--hemoprotein reductase] + dioxygen → 17alpha-hydroxypregnenolone + oxidized [NADPH--hemoprotein reductase] + water + hydron
→ Balance undeterminable
- 17alpha-hydroxypregnenolone + reduced [NADPH--hemoprotein reductase] + dioxygen → 3beta-hydroxyandrost-5-en-17-one + acetate + oxidized [NADPH--hemoprotein reductase] + water + 2 hydron
→ Balance undeterminable
- 17alpha-hydroxyprogesterone + reduced [NADPH--hemoprotein reductase] + dioxygen → 16alpha,17alpha-dihydroxyprogesterone + oxidized [NADPH--hemoprotein reductase] + water + hydron
→ Balance undeterminable
- 16alpha,17alpha-dihydroxyprogesterone + reduced [NADPH--hemoprotein reductase] + dioxygen → 6beta,16alpha,17alpha-trihydroxyprogesterone + oxidized [NADPH--hemoprotein reductase] + water + hydron
→ Balance undeterminable
- 16alpha,17alpha-dihydroxypregnenolone + reduced [NADPH--hemoprotein reductase] + dioxygen → 3beta,16alpha-dihydroxy-androst-5-en-17-one + acetate + oxidized [NADPH--hemoprotein reductase] + water + 2 hydron
→ Balance undeterminable
- androst-4-ene-3,17-dione + reduced [NADPH--hemoprotein reductase] + dioxygen → 16alpha-hydroxyandrost-4-ene-3,17-dione + oxidized [NADPH--hemoprotein reductase] + water + hydron
→ Balance undeterminable
- CHEBI:61313 + reduced [NADPH--hemoprotein reductase] + dioxygen → CHEBI:138141 + oxidized [NADPH--hemoprotein reductase] + water + hydron
→ Balance undeterminable