Reactions
5,6,7,8-tetrahydrofolic acid
33 reactions
- MAM00209m + biotin + CHEBI:1146900 + MAM01600m + ferroheme c di-L-cysteine(2-) residue + FADH2 + (S)-carnitine + NADH(2-) + NADPH(4-) + riboflavin + 5,6,7,8-tetrahydrobiopterin + 5,6,7,8-tetrahydrofolic acid + ubiquinol + 0.1 MAM03139c + 0.1 MAM03140c + 0.1 MAM03143c → MAM01602c
→ Balance undeterminable
- water + 5,6,7,8-tetrahydrofolic acid ⇌ water + 5,6,7,8-tetrahydrofolic acid
⇌ Balanced
- L-seryl residue + 5,6,7,8-tetrahydrofolic acid ⇌ (6R)-5,10-methylenetetrahydrofolic acid + glycine + water
⇌ Balanced · EC 2.1.2.1
- S-adenosyl-L-methionine + 5,6,7,8-tetrahydrofolic acid → 5-methyltetrahydrofolic acid + CHEBI:16680
→ Balanced · EC 2.1.1.8
- 5-methyltetrahydrofolic acid + homocysteine → proton + L-methionine + 5,6,7,8-tetrahydrofolic acid
→ Balanced · EC 2.1.1.13
- 5,6,7,8-tetrahydrofolic acid ⇌ 5,6,7,8-tetrahydrofolic acid
⇌ Balanced
- formaldehyde + 5,6,7,8-tetrahydrofolic acid → (6R)-5,10-methylenetetrahydrofolic acid + water
→ Balanced
- 5-methyltetrahydrofolic acid + Se-methylselenocysteine → proton + selenomethionine + 5,6,7,8-tetrahydrofolic acid
→ Balanced · EC 2.1.1.13
- 5-methyltetrahydrofolic acid + Se-methylselenocysteine → proton + selenomethionine + 5,6,7,8-tetrahydrofolic acid
→ Balanced · EC 2.1.1.13
- 7,8-dihydrofolate + proton + NADH(2-) ⇌ NAD(+) + 5,6,7,8-tetrahydrofolic acid
⇌ Balanced · EC 1.5.1.3
- 7,8-dihydrofolate + proton + NADPH(4-) ⇌ NADP(3-) + 5,6,7,8-tetrahydrofolic acid
⇌ Balanced · EC 1.5.1.3
- 7,8-dihydrofolate + proton + NADPH(4-) ⇌ NADP(3-) + 5,6,7,8-tetrahydrofolic acid
⇌ Balanced · EC 1.5.1.3
- 10-formyltetrahydrofolic acid + water + NADP(3-) → carbon dioxide + proton + NADPH(4-) + 5,6,7,8-tetrahydrofolic acid
→ Balanced · EC 1.5.1.6
- ATP + formic acid + 5,6,7,8-tetrahydrofolic acid → 10-formyltetrahydrofolic acid + ADP + phosphate(3-)
→ Balanced · EC 3.5.4.9, 6.3.4.3
- ATP + formic acid + 5,6,7,8-tetrahydrofolic acid → 10-formyltetrahydrofolic acid + ADP + phosphate(3-)
→ Balanced · EC 3.5.4.9, 6.3.4.3
- 5-formimidoyltetrahydrofolate + L-glutamate(1-) ⇌ proton + N-formimidoyl-L-glutamate + 5,6,7,8-tetrahydrofolic acid
⇌ Balanced · EC 2.1.2.5
- (6R)-5,10-methylenetetrahydrofolic acid + glycine + water ⇌ L-seryl residue + 5,6,7,8-tetrahydrofolic acid
⇌ Balanced · EC 2.1.2.1
- 10-formyltetrahydrofolic acid + N(1)-(5-phospho-D-ribosyl)glycinamide → proton + N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide + 5,6,7,8-tetrahydrofolic acid
→ Balanced · EC 2.1.2.2
- 10-formyltetrahydrofolic acid + 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide ⇌ CHEBI:18381 + 5,6,7,8-tetrahydrofolic acid
⇌ Balanced · EC 2.1.2.3
- 10-formyltetrahydrofolic acid + Met-tRNA(Met) → MAM02576c + 5,6,7,8-tetrahydrofolic acid
→ Balance undeterminable · EC 2.1.2.9
- 6 ATP + 6 L-glutamate(1-) + 5,6,7,8-tetrahydrofolic acid → 6 ADP + 6 proton + 6 phosphate(3-) + MAM02981c
→ Balanced · EC 6.3.2.17
- 6 water + MAM02981c → 6 L-glutamate(1-) + 5,6,7,8-tetrahydrofolic acid
→ Balanced · EC 3.4.19.9
- water + 5,6,7,8-tetrahydrofolic acid ⇌ water + 5,6,7,8-tetrahydrofolic acid
⇌ Balanced
- 4 ATP + 4 L-glutamate(1-) + 5,6,7,8-tetrahydrofolic acid → 4 ADP + 4 proton + MAM02692c + 4 phosphate(3-)
→ Balanced · EC 6.3.2.17
- 4 ATP + 4 L-glutamate(1-) + 5,6,7,8-tetrahydrofolic acid → 4 ADP + 4 proton + MAM02692m + 4 phosphate(3-)
→ Balanced · EC 6.3.2.17
- 4 water + MAM02692e → 4 L-glutamate(1-) + 5,6,7,8-tetrahydrofolic acid
→ Balanced · EC 3.4.19.9
- 4 water + MAM02692l → 4 L-glutamate(1-) + 5,6,7,8-tetrahydrofolic acid
→ Balanced · EC 3.4.19.9
- 5,6,7,8-tetrahydrofolic acid ⇌ 5,6,7,8-tetrahydrofolic acid
⇌ Balanced
- FAD + CHEBI:15611 + 5,6,7,8-tetrahydrofolic acid → (6R)-5,10-methylenetetrahydrofolic acid + FADH2 + glycine
→ Balanced · EC 1.5.8.3
- S(8)-aminomethyldihydrolipoamide + 5,6,7,8-tetrahydrofolic acid → MAM00208m + (6R)-5,10-methylenetetrahydrofolic acid + proton + ammonium
→ Unbalanced · EC 1.8.1.4, 2.1.2.10
- 5,6,7,8-tetrahydrofolic acid ⇌
⇌ Balance undeterminable
- MAM01100c + L-glutamate(1-) → proton + 5,6,7,8-tetrahydrofolic acid + MAM10011c
→ Balanced · EC 2.1.2.5
- 0.0345 11-cis-retinol + 0.0172 all-trans-18-hydroxyretinoate + 0.0172 all-trans-18-hydroxyretinoate + 0.0172 MAM00611c + 0.0172 MAM00611m + 0.0172 MAM00622c + 0.0172 MAM00622m + 0.0345 MAM00766c + 0.0172 MAM01008c + 0.0172 MAM01008r + 0.0172 MAM01022c + 0.0172 MAM01022r + 0.0172 MAM01024c + 0.0172 MAM01024r + 0.0345 MAM01026r + 0.0172 MAM01028c + 0.0172 MAM01028r + 0.0172 MAM01030c + 0.0172 MAM01030r + 0.0172 all-trans-4-oxoretinoate + 0.0172 all-trans-4-oxoretinoate + 0.0345 all-trans-4-oxoretinol + 0.0345 MAM01060c + 0.0345 9-cis-retinol + 0.0345 biotin + 0.0345 MAM01600m + 0.0345 FADH2 + 0.0345 MAM01924c + 0.0345 heme b + 0.0345 (S)-carnitine + 0.0345 (R)-lipoate + 0.0345 MAM02624c + 0.0345 CHEBI:18405 + 0.0345 riboflavin + 0.0345 5,6,7,8-tetrahydrobiopterin + 0.0345 5,6,7,8-tetrahydrofolic acid + 0.0345 thiamine(1+) diphosphate + 0.0345 ubiquinol → MAM10012c
→ Balance undeterminable