Reactions

water

10,234 reactions

• cholesterol sulfate + water → CHEBI:1307929 + proton + sulfate

  → Balanced · EC 3.1.6.2

• CHEBI:1307929 + proton + NADPH(4-) + dioxygen → (22S)-22-hydroxycholesterol + water + NADP(3-)

  → Balanced · EC 1.14.13.-

• (22S)-22-hydroxycholesterol + proton + NADPH(4-) + dioxygen → (20R,22R)-20,22-dihydroxycholesterol + water + NADP(3-)

  → Balanced · EC 1.14.15.16

• (20R,22R)-20,22-dihydroxycholesterol + proton + NADPH(4-) + dioxygen → 2 water + 4-methylpentanal + NADP(3-) + pregnenolone

  → Balanced · EC 1.14.15.16

• CHEBI:1307929 + 2 proton + dioxygen + 2 reduced adrenodoxin → MAM00592c + water + 2 MAM02663c

  → Balance undeterminable · EC 1.14.15.6

• MAM00592c + proton + NADPH(4-) + dioxygen → (20R)-17alpha,20-dihydroxycholesterol + water + NADP(3-)

  → Balanced · EC 1.14.14.19

• (20R)-17alpha,20-dihydroxycholesterol + 4 proton + 2 dioxygen + 4 reduced adrenodoxin → 17alpha-hydroxypregnenolone + 3 water + 4-methylpentanal + 4 MAM02663c

  → Balance undeterminable · EC 1.14.15.6

• MAM00592c + 2 proton + dioxygen + 2 reduced adrenodoxin → (20R,22R)-20,22-dihydroxycholesterol + water + 2 MAM02663c

  → Balance undeterminable · EC 1.14.15.6

• proton + NADPH(4-) + dioxygen + pregnenolone → MAM00605c + water + NADP(3-)

  → Balanced · EC 1.14.14.16

• 21-hydroxyprogesterone + 2 proton + dioxygen + 2 MAM02828c → corticosterone + water + 2 MAM02665c

  → Balance undeterminable · EC 1.14.15.4

• proton + NADPH(4-) + dioxygen + pregnenolone → 7alpha-hydroxypregnenolone + water + NADP(3-)

  → Balanced · EC 1.14.14.29

• proton + NADPH(4-) + dioxygen + pregnenolone → 17alpha-hydroxypregnenolone + water + NADP(3-)

  → Balanced · EC 1.14.14.19

• proton + NADPH(4-) + dioxygen + pregnenolone → 17alpha-hydroxypregnenolone + water + NADP(3-)

  → Balanced · EC 1.14.14.19

• 17alpha-hydroxypregnenolone + proton + NADPH(4-) + dioxygen → 17alpha,21-dihydroxypregnenolone + water + NADP(3-)

  → Balanced · EC 1.14.14.16

• 17alpha,21-dihydroxypregnenolone + 2 proton + dioxygen + 2 MAM02828c → MAM00283c + water + 2 MAM02665c

  → Balance undeterminable · EC 1.14.15.4

• water + pregnenolone sulfate → proton + pregnenolone + sulfate

  → Balanced · EC 3.1.6.2

• 17alpha-hydroxypregnenolone + 2 proton + 2 NADPH(4-) + dioxygen → acetaldehyde + 3beta-hydroxyandrost-5-en-17-one + 2 water + 2 NADP(3-)

  → Balanced · EC 1.14.14.32

• 17alpha-hydroxypregnenolone + NADPH(4-) + dioxygen → acetate + 3beta-hydroxyandrost-5-en-17-one + water + NADP(3-)

  → Balanced · EC 1.14.99.-

• 17alpha-hydroxypregnenolone + NADPH(4-) + dioxygen ⇌ acetate + 3beta-hydroxyandrost-5-en-17-one + water + NADP(3-)

  ⇌ Balanced · EC 1.14.99.-

• MAM00407c + water → 17alpha-hydroxypregnenolone + proton + sulfate

  → Balanced · EC 3.1.6.2

• proton + NADPH(4-) + dioxygen + progesterone → 17alpha-hydroxyprogesterone + water + NADP(3-)

  → Balanced · EC 1.14.14.19

• 17alpha-hydroxyprogesterone + NADPH(4-) + dioxygen → androst-4-ene-3,17-dione + acetate + water + NADP(3-)

  → Balanced · EC 1.14.99.-

• 17alpha-hydroxyprogesterone + NADPH(4-) + dioxygen ⇌ androst-4-ene-3,17-dione + acetate + water + NADP(3-)

  ⇌ Balanced · EC 1.14.99.-

• 17alpha-hydroxyprogesterone + proton + NADPH(4-) + dioxygen → 11-deoxycortisol + water + NADP(3-)

  → Balanced · EC 1.14.14.16

• 17alpha-hydroxyprogesterone + proton + NADPH(4-) + dioxygen → MAM00603c + water + NADP(3-)

  → Balanced · EC 1.14.15.4

• cortisol + water + NADP(3-) → MAM00603c + proton + NADPH(4-) + dioxygen

  → Balanced · EC 1.14.14.16

• MAM00603c + water + NADP(3-) → 11beta-hydroxyprogesterone + proton + NADPH(4-) + dioxygen

  → Balanced · EC 1.14.14.19

• 11beta-hydroxyprogesterone + proton + NADPH(4-) + dioxygen → corticosterone + water + NADP(3-)

  → Balanced · EC 1.14.14.16

• proton + NADPH(4-) + dioxygen + progesterone → 11beta-hydroxyprogesterone + water + NADP(3-)

  → Balanced · EC 1.14.15.4

• 11-deoxycortisol + proton + NADPH(4-) + dioxygen → cortisol + water + NADP(3-)

  → Balanced · EC 1.14.15.4

• cortisol + proton + 2 NADPH(4-) + dioxygen → 11beta-hydroxyandrost-4-ene-3,17-dione + acetate + 2 water + 2 NADP(3-)

  → Balanced · EC 1.14.15.4, 1.14.14.19

• cortisol + proton + 2 NADPH(4-) + dioxygen → 11beta-hydroxyandrost-4-ene-3,17-dione + acetate + 2 water + 2 NADP(3-)

  → Balanced · EC 1.14.15.4, 1.14.99.-

• cortisol + proton + 2 NADPH(4-) + dioxygen → 11beta-hydroxyandrost-4-ene-3,17-dione + acetate + 2 water + 2 NADP(3-)

  → Balanced · EC 1.14.15.4, 1.14.99.-

• 3alpha-hydroxy-5alpha-pregnan-20-one + proton + NADH(2-) + dioxygen → MAM00604c + water + NAD(+)

  → Balanced · EC 1.14.14.16

• proton + NADPH(4-) + dioxygen + progesterone → 21-hydroxyprogesterone + water + NADP(3-)

  → Balanced · EC 1.14.14.16

• 21-hydroxyprogesterone + proton + NADPH(4-) + dioxygen → corticosterone + water + NADP(3-)

  → Balanced · EC 1.14.15.4

• corticosterone + proton + NADPH(4-) + dioxygen → MAM00429m + water + NADP(3-)

  → Balanced · EC 1.14.15.5

• MAM00429m + proton + NADPH(4-) + dioxygen → aldosterone + 2 water + NADP(3-)

  → Balanced · EC 1.14.15.5

• androsterone 3alpha-sulfate + water ⇌ androsterone + proton + sulfate

  ⇌ Balanced · EC 3.1.6.2

• water + MAM03108e → MAM01967e + 2 proton + UMP

  → Balanced · EC 3.6.1.45

• L-arginine + 2 NADPH(4-) + 2 dioxygen → L-citrulline + 2 water + 2 NADP(3-) + nitric oxide

  → Unbalanced · EC 1.14.13.39

• 17beta-hydroxy-5alpha-androstan-3-one + proton + sulfate ⇌ 5alpha-dihydrotestosterone sulfate + water

  ⇌ Balanced · EC 3.1.6.2

• 2 proton + dioxygen + testosterone → MAM00432c + water

  → Unbalanced · EC 1.14.14.1

• MAM00432c + 2 proton + dioxygen → 19-oxotestosterone + 2 water

  → Unbalanced · EC 1.14.14.1

• 19-oxotestosterone + NADPH(4-) + dioxygen → 17beta-estradiol + formic acid + water + NADP(3-)

  → Balanced · EC 1.14.14.1

• androst-4-ene-3,17-dione + 2 proton + dioxygen → 19-hydroxyandrost-4-ene-3,17-dione + water

  → Unbalanced · EC 1.14.14.1

• 19-hydroxyandrost-4-ene-3,17-dione + 2 proton + dioxygen → 19-oxo-androst-4-ene-3,17-dione + 2 water

  → Unbalanced · EC 1.14.14.1

• 19-oxo-androst-4-ene-3,17-dione + NADPH(4-) + dioxygen → estrone + formic acid + water + NADP(3-)

  → Balanced · EC 1.14.14.1

• estrone 3-sulfate + water → estrone + proton + sulfate

  → Balanced · EC 3.1.6.1, 3.1.6.2

• 17beta-estradiol + proton + NADPH(4-) + dioxygen → 2-hydroxy-17beta-estradiol + water + NADP(3-)

  → Balanced · EC 1.14.14.1

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