Proteins/UNIPROT:Q32MQ0

ZNF750

ProteinUNIPROT:Q32MQ0

Transcription factor involved in epidermis differentiation. Required for terminal epidermal differentiation: acts downstream of p63/TP63 and activates expression of late epidermal differentiation genes. Specifically binds to the promoter of KLF4 and promotes its expression..

Function from UniProtKB (Q32MQ0), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

GenCC submitters' classifications

1 row

seborrhea-like dermatitis with psoriasiform elements has a germline basis in ZNF750DiseaseGenCC HGNC:25843|MONDO:0012446Inferred only

Statements

17 statements

17 statements · 3 reference databases · Subject: ZNF750 · Sources: gene ontology, Hetionet, Reactome

Order

ZNF750 covaries with CCDC57ProteinHetionet hetionet:covaries:284001-79755Inferred only
ZNF750 covaries with GALNT9ProteinHetionet hetionet:covaries:50614-79755Inferred only
ZNF750 covaries with MEGF6ProteinHetionet hetionet:covaries:1953-79755Inferred only
PCNT covaries with ZNF750ProteinHetionet hetionet:covaries:5116-79755Inferred only
PHRF1 covaries with ZNF750ProteinHetionet hetionet:covaries:57661-79755Inferred only
ZNF750 covaries with PLCH2ProteinHetionet hetionet:covaries:79755-9651Inferred only
SLC19A1 covaries with ZNF750ProteinHetionet hetionet:covaries:6573-79755Inferred only
ZNF750 covaries with TBCDProteinHetionet hetionet:covaries:6904-79755Inferred only
ZNF750 covaries with TEPSINProteinHetionet hetionet:covaries:146705-79755Inferred only
ZNF623 covaries with ZNF750ProteinHetionet hetionet:covaries:79755-9831Inferred only
ZNF750 participates in Gene expression (Transcription)PathwayReactome R-HSA-74160Inferred only
ZNF750 participates in Generic Transcription PathwayPathwayReactome R-HSA-212436Inferred only

Show the remaining 5

ZNF750 participates in RNA Polymerase II TranscriptionPathwayReactome R-HSA-73857Inferred only
ZNF750 regulates negative regulation of epithelial to mesenchymal transitionBiological processgene ontology Q32MQ0|GO:0010719Inferred only
ZNF750 regulates negative regulation of transcription by RNA polymerase IIBiological processgene ontology Q32MQ0|GO:0000122Inferred only
ZNF750 regulates positive regulation of transcription by RNA polymerase IIBiological processgene ontology Q32MQ0|GO:0045944Inferred only
ZNF750 regulates regulation of transcription by RNA polymerase IIBiological processgene ontology Q32MQ0|GO:0006357Inferred only

Other names

1 name

Resolves to: ZNF750

Also called: Zinc finger protein 750

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