Loading the page.
Proteins/UNIPROT:Q86Y38
Catalyzes the first step in the biosynthesis of chondroitin sulfate and dermatan sulfate proteoglycans, such as DCN. Transfers D-xylose from UDP-D-xylose to specific serine residues of the core protein. Required for normal embryonic and postnatal skeleton development, especially of the long bones. Required for normal maturation of chondrocytes during bone development, and normal onset of ossification (By similarity)..
Function from UniProtKB (Q86Y38), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
3 rows
11 statements
11 statements · 6 reference databases · Subject: XYLT1 · Sources: Hetionet, Human-GEM, Reactome, Rhea, UniProt, WikiPathways
2 reactions
MAM00205r+UDP-alpha-D-xyloseproton+UDP+MAM03156r
Reaction pageLeft to rightBalance undeterminableEC 2.4.2.26endoplasmic reticulum
Human-GEM MAR07200CC BY 4.0Reference data
L-seryl-[protein]+UDP-alpha-D-xylose3-O-(beta-D-xylosyl)-L-seryl-[protein]+UDP+hydron
Catalysed by XYLT1 or
5 names
Resolves to: XYLT1
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:50192CC BY 4.0Reference data