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Proteins/UNIPROT:P46094

XCR1

Protein·UNIPROT:P46094

Open in the graph

Receptor for chemokines SCYC1 and SCYC2. Subsequently transduces a signal by increasing the intracellular calcium ions level. Receptor for XCL1/Lymphotactin..

Function from UniProtKB (P46094), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Inferred

Inferred — not reported by a source. Evidence key

Statements

14 statements

14 statements · 4 reference databases · Subject: XCR1 · Sources: gene ontology, Hetionet, Reactome, WikiPathways

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XCR1 interacts with XCL1ProteinHetionet hetionet:interacts:2829-6375Inferred only
XCR1 interacts with XCL2ProteinHetionet hetionet:interacts:2829-6846Inferred only
XCR1 participates in Chemokine receptors bind chemokinesPathwayReactome R-HSA-380108Inferred only
XCR1 participates in Chemokine signalingPathwayWikiPathways WP3929Inferred only
XCR1 participates in Class A/1 (Rhodopsin-like receptors)PathwayReactome R-HSA-373076Inferred only
XCR1 participates in Cytokine cytokine receptor interactionPathwayWikiPathways WP5473Inferred only
XCR1 participates in G alpha (q) signalling eventsPathwayReactome R-HSA-416476Inferred only
XCR1 participates in GPCR downstream signallingPathwayReactome R-HSA-388396Inferred only
XCR1 participates in GPCR ligand bindingPathwayReactome R-HSA-500792Inferred only
XCR1 participates in GPCRs class A rhodopsin likePathwayWikiPathways WP455Inferred only
XCR1 participates in Peptide ligand-binding receptorsPathwayReactome R-HSA-375276Inferred only
XCR1 participates in Signal TransductionPathwayReactome R-HSA-162582Inferred only

Show the remaining 2

XCR1 participates in Signaling by GPCRPathwayReactome R-HSA-372790Inferred only
XCR1 regulates positive regulation of cytosolic calcium ion concentrationBiological processgene ontology P46094|GO:0007204Inferred only

Other names

5 names

Resolves to: XCR1

Also called: CCXCR1G protein-coupled receptor 5GPR5Lymphotactin receptorXC chemokine receptor 1

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