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Proteins/UNIPROT:A4D1P6
Functions as a negative regulator of the PI3 kinase/PI3K activity associated with endosomal membranes via BECN1, a core subunit of the PI3K complex. By modifying the phosphatidylinositol 3-phosphate/PtdInsP3 content of endosomal membranes may regulate endosome fusion, recycling, sorting and early to late endosome transport. It is for instance, required for the delivery of cargos like BST2/tetherin from early to late endosome and thereby participates indirectly to their degradation by the lysosome. May play a role in meiosis (By similarity)..
Function from UniProtKB (A4D1P6), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
1 row
10 statements
10 statements · 3 reference databases · Subject: WDR91 · Sources: gene ontology, Hetionet, Reactome
1 name
Resolves to: WDR91