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Proteins/UNIPROT:Q9H267
May play a role in vesicle-mediated protein trafficking to lysosomal compartments and in membrane docking/fusion reactions of late endosomes/lysosomes. Required for proper trafficking and targeting of the collagen-modifying enzyme lysyl hydroxylase 3 (LH3) to intracellular collagen. Mediates phagolysosomal fusion in macrophages. Proposed to be involved in endosomal maturation implicating VIPAS39. In epithelial cells, the VPS33B:VIPAS39 complex may play a role in the apical recycling pathway and in the maintenance of the apical-basolateral polarity. Seems to be involved in the sorting of specific cargos from the trans-Golgi network to alpha-granule-destined multivesicular bodies (MVBs) promoting MVBs maturation in megakaryocytes (By similarity)..
Function from UniProtKB (Q9H267), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
3 rows
19 statements
19 statements · 3 reference databases · Subject: VPS33B · Sources: gene ontology, Hetionet, Reactome
2 names
Resolves to: VPS33B