Proteins/UNIPROT:Q14D04

VEPH1

ProteinUNIPROT:Q14D04

Interacts with TGF-beta receptor type-1 (TGFBR1) and inhibits dissociation of activated SMAD2 from TGFBR1, impeding its nuclear accumulation and resulting in impaired TGF-beta signaling. May also affect FOXO, Hippo and Wnt signaling..

Function from UniProtKB (Q14D04), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Statements

13 statements

13 statements · 2 reference databases · Subject: VEPH1 · Sources: gene ontology, Hetionet

Order

ANKRD26 covaries with VEPH1ProteinHetionet hetionet:covaries:22852-79674Inferred only
VEPH1 covaries with CAPS2ProteinHetionet hetionet:covaries:79674-84698Inferred only
VEPH1 covaries with CCDC15ProteinHetionet hetionet:covaries:79674-80071Inferred only
PCDHB10 covaries with VEPH1ProteinHetionet hetionet:covaries:56126-79674Inferred only
VEPH1 covaries with SOX6ProteinHetionet hetionet:covaries:55553-79674Inferred only
ACVR1 interacts with VEPH1ProteinHetionet hetionet:interacts:79674-90Inferred only
BMPR1B interacts with VEPH1ProteinHetionet hetionet:interacts:658-79674Inferred only
EIF1B interacts with VEPH1ProteinHetionet hetionet:interacts:10289-79674Inferred only
SMAD1 interacts with VEPH1ProteinHetionet hetionet:interacts:4086-79674Inferred only
TGFBR1 interacts with VEPH1ProteinHetionet hetionet:interacts:7046-79674Inferred only
VEPH1 regulates negative regulation of SMAD protein signal transductionBiological processgene ontology Q14D04|GO:0060392Inferred only
VEPH1 regulates negative regulation of transforming growth factor beta receptor signaling pathwayBiological processgene ontology Q14D04|GO:0030512Inferred only

Show the remaining 1

VEPH1 regulates regulation of signal transductionBiological processgene ontology Q14D04|GO:0009966Inferred only

Other names

5 names

Resolves to: VEPH1

Also called: KIAA1692meltedProtein meltedVentricular zone-expressed PH domain-containing protein homolog 1VEPH

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