Proteins/UNIPROT:Q68CQ4

UTP25

ProteinUNIPROT:Q68CQ4

Component of the ribosomal small subunit processome for the biogenesis of ribosomes, functions in pre-ribosomal RNA (pre-rRNA) processing (By similarity). Essential for embryonic development in part through the regulation of p53 pathway. Controls the expansion growth of digestive organs and liver. Also involved in the sympathetic neuronal development (By similarity). Mediates, with CAPN3, the proteasome-independent degradation of p53/TP53..

Function from UniProtKB (Q68CQ4), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Statements

24 statements

24 statements · 3 reference databases · Subject: UTP25 · Sources: gene ontology, Hetionet, Reactome

Order

ANKRD34C covaries with UTP25ProteinHetionet hetionet:covaries:27042-390616Inferred only
CCDC15 covaries with UTP25ProteinHetionet hetionet:covaries:27042-80071Inferred only
CEACAM19 covaries with UTP25ProteinHetionet hetionet:covaries:27042-56971Inferred only
DCAF16 covaries with UTP25ProteinHetionet hetionet:covaries:27042-54876Inferred only
FBXL22 covaries with UTP25ProteinHetionet hetionet:covaries:27042-283807Inferred only
SCRT2 covaries with UTP25ProteinHetionet hetionet:covaries:27042-85508Inferred only
ZNF514 covaries with UTP25ProteinHetionet hetionet:covaries:27042-84874Inferred only
APP interacts with UTP25ProteinHetionet hetionet:interacts:27042-351Inferred only
MAGEA11 interacts with UTP25ProteinHetionet hetionet:interacts:27042-4110Inferred only
UTP25 interacts with SIRT7ProteinHetionet hetionet:interacts:27042-51547Inferred only
SUMO2 interacts with UTP25ProteinHetionet hetionet:interacts:27042-6613Inferred only
UBC interacts with UTP25ProteinHetionet hetionet:interacts:27042-7316Inferred only

Show the remaining 12

UTP25 participates in Major pathway of rRNA processing in the nucleolus and cytosolPathwayReactome R-HSA-6791226Inferred only
UTP25 participates in Metabolism of RNAPathwayReactome R-HSA-8953854Inferred only
UTP25 participates in rRNA modification in the nucleus and cytosolPathwayReactome R-HSA-6790901Inferred only
UTP25 participates in rRNA processingPathwayReactome R-HSA-72312Inferred only
UTP25 participates in rRNA processing in the nucleus and cytosolPathwayReactome R-HSA-8868773Inferred only
UTP25 regulates positive regulation of embryonic developmentBiological processgene ontology Q68CQ4|GO:0040019Inferred only
ARL1 increases the expression of UTP25ProteinHetionet hetionet:regulates:400-27042Inferred only
LMO4 increases the expression of UTP25ProteinHetionet hetionet:regulates:8543-27042Inferred only
POLR2I increases the expression of UTP25ProteinHetionet hetionet:regulates:5438-27042Inferred only
SF3B1 increases the expression of UTP25ProteinHetionet hetionet:regulates:23451-27042Inferred only
SNRPD1 increases the expression of UTP25ProteinHetionet hetionet:regulates:6632-27042Inferred only
STAT1 increases the expression of UTP25ProteinHetionet hetionet:regulates:6772-27042Inferred only

Other names

5 names

Resolves to: UTP25

Also called: C1orf107DEFDIEXFDigestive organ expansion factor homologUTP25 small subunit processor component

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