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Proteins/UNIPROT:Q9BXA7

TSSK1B

Protein·UNIPROT:Q9BXA7

Open in the graph

Testis-specific serine/threonine-protein kinase required during spermatid development. Phosphorylates 'Ser-288' of TSKS. Involved in the late stages of spermatogenesis, during the reconstruction of the cytoplasm. During spermatogenesis, required for the transformation of a ring-shaped structure around the base of the flagellum originating from the chromatoid body..

Function from UniProtKB (Q9BXA7), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Inferred

Inferred — not reported by a source. Evidence key

Statements

7 statements

7 statements · 2 reference databases · Subject: TSSK1B · Sources: Hetionet, UniProt

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CHEK2 interacts with TSSK1BProteinHetionet hetionet:interacts:11200-83942Inferred only
HSP90AA1 interacts with TSSK1BProteinHetionet hetionet:interacts:3320-83942Inferred only
HSP90AB1 interacts with TSSK1BProteinHetionet hetionet:interacts:3326-83942Inferred only
TGFBR1 interacts with TSSK1BProteinHetionet hetionet:interacts:7046-83942Inferred only
TGFBR2 interacts with TSSK1BProteinHetionet hetionet:interacts:7048-83942Inferred only
TSSK1B increases the expression of LCN2ProteinHetionet hetionet:regulates:83942-3934Inferred only
TSSK1B requires the cofactor magnesium(2+)CompoundUniProt Q9BXA7Inferred only

Reactions

2 reactions

L-seryl-[protein]+ATP(4-)O-phospho-L-seryl-[protein]+ADP(3-)+hydron
Catalysed by SGK1 or CDC7 or PLK4 or STK25 or CIT or RIOK3 or MAP2K7 or CHEK1 or BCKDK or IKBKB or CASK or AURKA and 347 more alternatives
Reaction pageLeft to right

Other names

11 names

Resolves to: TSSK1B

Also called: 22ASerine/threonine-protein kinase 22ASPOGA1SPOGA4STK22ASTK22DTestis-specific kinase 1TSK-1TSK1TSSK-1TSSK1

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Balance undeterminable

Rhea RHEA:17989CC BY 4.0Reference data

L-threonyl-[protein]+ATP(4-)O-phospho-L-threonyl-[protein]+ADP(3-)+hydron

Catalysed by SGK1 or CDC7 or PLK4 or STK25 or CIT or RIOK3 or MAP2K7 or CHEK1 or IKBKB or CASK or AURKA or GAK and 341 more alternatives

Reaction pageLeft to rightBalance undeterminable

Rhea RHEA:46608CC BY 4.0Reference data