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Proteins/UNIPROT:Q6PIZ9

TRAT1

Protein·UNIPROT:Q6PIZ9

Open in the graph

Stabilizes the TCR (T-cell antigen receptor)/CD3 complex at the surface of T-cells..

Function from UniProtKB (Q6PIZ9), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Inferred

Inferred — not reported by a source. Evidence key

Statements

26 statements

26 statements · 3 reference databases · Subject: TRAT1 · Sources: gene ontology, Hetionet, Reactome

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CD247 interacts with TRAT1ProteinHetionet hetionet:interacts:50852-919Inferred only
CD3E interacts with TRAT1ProteinHetionet hetionet:interacts:50852-916Inferred only
FYN interacts with TRAT1ProteinHetionet hetionet:interacts:2534-50852Inferred only
GRB2 interacts with TRAT1ProteinHetionet hetionet:interacts:2885-50852Inferred only
LCK interacts with TRAT1ProteinHetionet hetionet:interacts:3932-50852Inferred only
LCP2 interacts with TRAT1ProteinHetionet hetionet:interacts:3937-50852Inferred only
LYN interacts with TRAT1ProteinHetionet hetionet:interacts:4067-50852Inferred only
PIK3R1 interacts with TRAT1ProteinHetionet hetionet:interacts:50852-5295Inferred only
SRC interacts with TRAT1ProteinHetionet hetionet:interacts:50852-6714Inferred only
TRAT1 participates in Adaptive Immune SystemPathwayReactome R-HSA-1280218Inferred only
TRAT1 participates in Constitutive Signaling by Aberrant PI3K in CancerPathwayReactome R-HSA-2219530Inferred only
TRAT1 participates in DiseasePathwayReactome R-HSA-1643685Inferred only

Show the remaining 14

TRAT1 participates in Diseases of signal transduction by growth factor receptors and second messengersPathwayReactome R-HSA-5663202Inferred only
TRAT1 participates in Downstream TCR signalingPathwayReactome R-HSA-202424Inferred only
TRAT1 participates in Immune SystemPathwayReactome R-HSA-168256Inferred only
TRAT1 participates in Intracellular signaling by second messengersPathwayReactome R-HSA-9006925Inferred only
TRAT1 participates in Negative regulation of the PI3K/AKT networkPathwayReactome R-HSA-199418Inferred only
TRAT1 participates in PI3K/AKT Signaling in CancerPathwayReactome R-HSA-2219528Inferred only
TRAT1 participates in PI5P, PP2A and IER3 Regulate PI3K/AKT SignalingPathwayReactome R-HSA-6811558Inferred only
TRAT1 participates in PIP3 activates AKT signalingPathwayReactome R-HSA-1257604Inferred only
TRAT1 participates in Signal TransductionPathwayReactome R-HSA-162582Inferred only
TRAT1 participates in TCR signalingPathwayReactome R-HSA-202403Inferred only
TRAT1 regulates negative regulation of receptor recyclingBiological processgene ontology Q6PIZ9|GO:0001920Inferred only
TRAT1 regulates negative regulation of transportBiological processgene ontology Q6PIZ9|GO:0051051Inferred only
TRAT1 regulates positive regulation of calcium-mediated signalingBiological processgene ontology Q6PIZ9|GO:0050850Inferred only
TRAT1 regulates positive regulation of T cell receptor signaling pathwayBiological processgene ontology Q6PIZ9|GO:0050862Inferred only

Other names

4 names

Resolves to: TRAT1

Also called: pp29/30T-cell receptor-interacting moleculeTCRIMTRIM

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