Proteins/UNIPROT:Q8WVR3

TRAPPC14

ProteinUNIPROT:Q8WVR3

Specific subunit of the TRAPP (transport protein particle) II complex, a highly conserved vesicle tethering complex that functions in late Golgi trafficking as a membrane tether. TRAPP II complex also has GEF activity toward RAB1A (By similarity). TRAPPC14 is dispensable for TRAPPII complex integrity but mediates RAB3IP preciliary vesicle trafficking to the mother centriole during ciliogenesis. Modulates YAP1 activity as transcriptional regulator..

Function from UniProtKB (Q8WVR3), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

GenCC submitters' classifications

1 row

autosomal recessive primary microcephaly has a germline basis in TRAPPC14DiseaseGenCC HGNC:25604|MONDO:0016660Inferred only

Statements

19 statements

19 statements · 2 reference databases · Subject: TRAPPC14 · Sources: gene ontology, Hetionet

Order

CCDC22 covaries with TRAPPC14ProteinHetionet hetionet:covaries:28952-55262Inferred only
TRAPPC14 covaries with CRXProteinHetionet hetionet:covaries:1406-55262Inferred only
ENHO covaries with TRAPPC14ProteinHetionet hetionet:covaries:375704-55262Inferred only
TRAPPC14 covaries with FCHSD1ProteinHetionet hetionet:covaries:55262-89848Inferred only
TRAPPC14 covaries with GPR26ProteinHetionet hetionet:covaries:2849-55262Inferred only
TRAPPC14 covaries with IRX1ProteinHetionet hetionet:covaries:55262-79192Inferred only
TRAPPC14 covaries with LPAR2ProteinHetionet hetionet:covaries:55262-9170Inferred only
TRAPPC14 covaries with MICOS13ProteinHetionet hetionet:covaries:125988-55262Inferred only
TRAPPC14 covaries with NAT14ProteinHetionet hetionet:covaries:55262-57106Inferred only
TRAPPC14 covaries with NUF2ProteinHetionet hetionet:covaries:55262-83540Inferred only
OR51M1 covaries with TRAPPC14ProteinHetionet hetionet:covaries:390059-55262Inferred only
PIM2 covaries with TRAPPC14ProteinHetionet hetionet:covaries:11040-55262Inferred only

Show the remaining 7

TRAPPC14 covaries with PLSCR3ProteinHetionet hetionet:covaries:55262-57048Inferred only
TRAPPC14 covaries with PPFIA3ProteinHetionet hetionet:covaries:55262-8541Inferred only
TRAPPC14 covaries with PSDProteinHetionet hetionet:covaries:55262-5662Inferred only
TRAPPC14 covaries with TRPC4APProteinHetionet hetionet:covaries:26133-55262Inferred only
TRAPPC14 covaries with ZFP90ProteinHetionet hetionet:covaries:146198-55262Inferred only
TMEM50A interacts with TRAPPC14ProteinHetionet hetionet:interacts:23585-55262Inferred only
TRAPPC14 regulates regulation of cell population proliferationBiological processgene ontology Q8WVR3|GO:0042127Inferred only

Other names

4 names

Resolves to: TRAPPC14

Also called: C7orf43MAP11Microtubule-associated protein 11Trafficking protein particle complex subunit 14

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