Proteins/UNIPROT:Q8WVT3

TRAPPC12

ProteinUNIPROT:Q8WVT3

Component of the TRAPP complex, which is involved in endoplasmic reticulum to Golgi apparatus trafficking at a very early stage. Also plays a role in chromosome congression, kinetochore assembly and stability and controls the recruitment of CENPE to the kinetochores..

Function from UniProtKB (Q8WVT3), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

GenCC submitters' classifications

1 row

early-onset progressive encephalopathy-hearing loss-pons hypoplasia-brain atrophy syndrome has a germline basis in TRAPPC12DiseaseGenCC HGNC:24284|MONDO:0044696Inferred only

Statements

21 statements

21 statements · 3 reference databases · Subject: TRAPPC12 · Sources: gene ontology, Hetionet, Reactome

Order

TRAPPC12 covaries with TPOProteinHetionet hetionet:covaries:51112-7173Inferred only
TRAPPC12 interacts with TRAPPC1ProteinHetionet hetionet:interacts:51112-58485Inferred only
TRAPPC10 interacts with TRAPPC12ProteinHetionet hetionet:interacts:51112-7109Inferred only
TRAPPC12 interacts with TRAPPC11ProteinHetionet hetionet:interacts:51112-60684Inferred only
TRAPPC2 interacts with TRAPPC12ProteinHetionet hetionet:interacts:51112-6399Inferred only
TRAPPC3 interacts with TRAPPC12ProteinHetionet hetionet:interacts:27095-51112Inferred only
TRAPPC12 interacts with TRAPPC3LProteinHetionet hetionet:interacts:100128327-51112Inferred only
TRAPPC12 interacts with TRAPPC4ProteinHetionet hetionet:interacts:51112-51399Inferred only
TRAPPC12 interacts with TRAPPC6AProteinHetionet hetionet:interacts:51112-79090Inferred only
TRAPPC12 interacts with TRAPPC6BProteinHetionet hetionet:interacts:122553-51112Inferred only
TRAPPC8 interacts with TRAPPC12ProteinHetionet hetionet:interacts:22878-51112Inferred only
TRAPPC12 interacts with TRAPPC9ProteinHetionet hetionet:interacts:51112-83696Inferred only

Show the remaining 9

UBC interacts with TRAPPC12ProteinHetionet hetionet:interacts:51112-7316Inferred only
TRAPPC12 participates in Membrane TraffickingPathwayReactome R-HSA-199991Inferred only
TRAPPC12 participates in RAB GEFs exchange GTP for GDP on RABsPathwayReactome R-HSA-8876198Inferred only
TRAPPC12 participates in Rab regulation of traffickingPathwayReactome R-HSA-9007101Inferred only
TRAPPC12 participates in Vesicle-mediated transportPathwayReactome R-HSA-5653656Inferred only
TRAPPC12 regulates positive regulation of protein localization to kinetochoreBiological processgene ontology Q8WVT3|GO:1905342Inferred only
TRAPPC12 regulates regulation of kinetochore assemblyBiological processgene ontology Q8WVT3|GO:0090234Inferred only
FEZ2 decreases the expression of TRAPPC12ProteinHetionet hetionet:regulates:9637-51112Inferred only
GTF2E2 increases the expression of TRAPPC12ProteinHetionet hetionet:regulates:2961-51112Inferred only

Other names

6 names

Resolves to: TRAPPC12

Also called: Tetratricopeptide repeat protein 15TPR repeat protein 15Trafficking of membranes and mitosisTRAMMTTC-15TTC15

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