Proteins/UNIPROT:Q93038

TNFRSF25

ProteinUNIPROT:Q93038

Receptor for TNFSF12/APO3L/TWEAK. Interacts directly with the adapter TRADD. Mediates activation of NF-kappa-B and induces apoptosis. May play a role in regulating lymphocyte homeostasis..

Function from UniProtKB (Q93038), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Statements

14 statements

14 statements · 4 reference databases · Subject: TNFRSF25 · Sources: gene ontology, Hetionet, Reactome, WikiPathways

Order

TNFRSF25 interacts with BAG4ProteinHetionet hetionet:interacts:8718-9530Inferred only
DAP3 interacts with TNFRSF25ProteinHetionet hetionet:interacts:7818-8718Inferred only
MAPK1 interacts with TNFRSF25ProteinHetionet hetionet:interacts:5594-8718Inferred only
TNFRSF25 interacts with TNFSF15ProteinHetionet hetionet:interacts:8718-9966Inferred only
TRADD interacts with TNFRSF25ProteinHetionet hetionet:interacts:8717-8718Inferred only
TNFRSF25 participates in ApoptosisPathwayWikiPathways WP254Inferred only
TNFRSF25 participates in Apoptosis modulation and signalingPathwayWikiPathways WP1772Inferred only
TNFRSF25 participates in Cytokine cytokine receptor interactionPathwayWikiPathways WP5473Inferred only
TNFRSF25 participates in Cytokine Signaling in Immune systemPathwayReactome R-HSA-1280215Inferred only
TNFRSF25 participates in Immune SystemPathwayReactome R-HSA-168256Inferred only
TNFRSF25 participates in TNFR2 non-canonical NF-kB pathwayPathwayReactome R-HSA-5668541Inferred only
TNFRSF25 participates in TNFs bind their physiological receptorsPathwayReactome R-HSA-5669034Inferred only

Show the remaining 2

TNFRSF25 participates in VEGFA VEGFR2 signalingPathwayWikiPathways WP3888Inferred only
TNFRSF25 regulates regulation of apoptotic processBiological processgene ontology Q93038|GO:0042981Inferred only

Other names

16 names

Resolves to: TNFRSF25

Also called: Apo-3APO3Apoptosis-inducing receptor AIRApoptosis-mediating receptor DR3Apoptosis-mediating receptor TRAMPDDR3Death receptor 3DR3LARDLymphocyte-associated receptor of deathProtein WSLProtein WSL-1TNFRSF12WSLWSL-1WSL1

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