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Proteins/UNIPROT:Q86WS5
Required for male fertility (By similarity). Plays a critical role in sperm capacitation and acrosome reactions during fertilization, and also plays a role in the regulation of proteins involved in spermatogenesis (By similarity). Regulates protein pathways that promote chromosomal synapsis formation, double-strand break repair, formation of the inner mitochondrial membrane cristae and apoptosis in developing sperm (By similarity). Required for normal sperm motility and binding to the zona pellucida, potentially via a role in ADAM3 protein maturation (By similarity)..
Function from UniProtKB (Q86WS5), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
3 statements
3 statements · 2 reference databases · Subject: TMPRSS12 · Sources: gene ontology, Hetionet
1 name
Resolves to: TMPRSS12