Proteins/UNIPROT:Q5T4T1

TMEM170B

ProteinUNIPROT:Q5T4T1

Negatively regulates the canonical Wnt signaling in breast cancer cells. Exerts an inhibitory effect on breast cancer growth by inhibiting CTNNB1 stabilization and nucleus translocation, which reduces the activity of Wnt targets..

Function from UniProtKB (Q5T4T1), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Statements

5 statements

5 statements · 2 reference databases · Subject: TMEM170B · Sources: gene ontology, Hetionet

Order

TMEM170B covaries with CIRBPProteinHetionet hetionet:covaries:100113407-1153Inferred only
TMEM170B covaries with HNRNPA0ProteinHetionet hetionet:covaries:100113407-10949Inferred only
NOTO covaries with TMEM170BProteinHetionet hetionet:covaries:100113407-344022Inferred only
TMEM170B covaries with TIA1ProteinHetionet hetionet:covaries:100113407-7072Inferred only
TMEM170B regulates negative regulation of canonical Wnt signaling pathwayBiological processgene ontology Q5T4T1|GO:0090090Inferred only

Other names

1 name

Resolves to: TMEM170B

Also called: Transmembrane protein 170B

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