Proteins/UNIPROT:Q86UB9

TMEM135

ProteinUNIPROT:Q86UB9

Involved in mitochondrial metabolism by regulating the balance between mitochondrial fusion and fission. May act as a regulator of mitochondrial fission that promotes DNM1L-dependent fission through activation of DNM1L. May be involved in peroxisome organization..

Function from UniProtKB (Q86UB9), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Statements

9 statements

9 statements · 2 reference databases · Subject: TMEM135 · Sources: gene ontology, Hetionet

Order

OR56A1 covaries with TMEM135ProteinHetionet hetionet:covaries:120796-65084Inferred only
UBC interacts with TMEM135ProteinHetionet hetionet:interacts:65084-7316Inferred only
TMEM135 regulates regulation of mitochondrial fissionBiological processgene ontology Q86UB9|GO:0090140Inferred only
F2R increases the expression of TMEM135ProteinHetionet hetionet:regulates:2149-65084Inferred only
GATAD1 increases the expression of TMEM135ProteinHetionet hetionet:regulates:57798-65084Inferred only
PDHX decreases the expression of TMEM135ProteinHetionet hetionet:regulates:8050-65084Inferred only
PLEKHJ1 decreases the expression of TMEM135ProteinHetionet hetionet:regulates:55111-65084Inferred only
PNKP decreases the expression of TMEM135ProteinHetionet hetionet:regulates:11284-65084Inferred only
SMARCB1 increases the expression of TMEM135ProteinHetionet hetionet:regulates:6598-65084Inferred only

Other names

2 names

Resolves to: TMEM135

Also called: Peroxisomal membrane protein 52PMP52

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