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Proteins/UNIPROT:Q9BV44
Catalytic subunit of the THUMPD3-TRM112 methyltransferase complex, that specifically mediates the S-adenosyl-L-methionine-dependent N(2)-methylation of guanosine nucleotide at position 6 (m2G6) in tRNAs. This is one of the major tRNA (guanine-N(2))-methyltransferases. Also catalyzes the S-adenosyl-L-methionine-dependent N(2)-methylation of guanosine nucleotide at position 7 of tRNA(Trp)..
Function from UniProtKB (Q9BV44), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
6 statements
6 statements · 2 reference databases · Subject: THUMPD3 · Sources: Bgee, Hetionet
2 reactions
CHEBI:74269+S-adenosyl-L-methionineCHEBI:74481+S-adenosyl-L-homocysteine+hydron
Catalysed by THUMPD3
Reaction pageLeft to rightBalanced
Rhea RHEA:51116CC BY 4.0Reference data
CHEBI:74269+S-adenosyl-L-methionineCHEBI:74481+S-adenosyl-L-homocysteine+hydron
Catalysed by THUMPD3
Reaction pageLeft to rightBalanced
3 names
Resolves to: THUMPD3