Loading the page.
Proteins/UNIPROT:O95947
T-box transcription factor that plays an essential role in the determination of the fate of axial stem cells: neural vs mesodermal. Acts in part by down-regulating, a specific enhancer (N1) of SOX2, to inhibit neural development. Seems to play also an essential role in left/right axis determination and acts through effects on Notch signaling around the node as well as through an effect on the morphology and motility of the nodal cilia (By similarity)..
Function from UniProtKB (O95947), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
3 rows
50 statements
50 statements · 4 reference databases · Subject: TBX6 · Sources: gene ontology, Hetionet, Reactome, WikiPathways
2 names
Resolves to: TBX6