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Proteins/UNIPROT:Q8NHG7
Negative regulator of the ER-associated degradation pathway (ERAD) of misfolded proteins. It competes with AMFR/gp78 for binding VCP/p97, and inhibits AMFR/gp78-VCP/p97 complex formation that is required for degradation of ERAD substrates. Involved in the regulation of adrenal cortisol and dehydroepiandrosterone (DHEA) biosynthesis..
Function from UniProtKB (Q8NHG7), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
23 statements
23 statements · 3 reference databases · Subject: SVIP · Sources: gene ontology, Hetionet, Reactome
1 name
Resolves to: SVIP