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Proteins/UNIPROT:P61266

STX1B

Protein·UNIPROT:P61266

Open in the graph

Potentially involved in docking of synaptic vesicles at presynaptic active zones. May mediate Ca(2+)-regulation of exocytosis acrosomal reaction in sperm (By similarity)..

Function from UniProtKB (P61266), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Inferred

Inferred — not reported by a source. Evidence key

GenCC submitters' classifications

2 rows

generalized epilepsy with febrile seizures plus has a germline basis in STX1BDiseaseGenCC HGNC:18539|MONDO:0018214Inferred only
generalized epilepsy with febrile seizures plus, type 9 has a germline basis in STX1BDiseaseGenCC HGNC:18539|MONDO:0014517Inferred only

Statements

28 statements

28 statements · 4 reference databases · Subject: STX1B · Sources: gene ontology, Hetionet, Reactome, WikiPathways

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SNAP23 interacts with STX1BProteinHetionet hetionet:interacts:112755-8773Inferred only
STXBP1 interacts with STX1BProteinHetionet hetionet:interacts:112755-6812Inferred only
UBC interacts with STX1BProteinHetionet hetionet:interacts:112755-7316Inferred only
UNC13B interacts with STX1BProteinHetionet hetionet:interacts:10497-112755Inferred only
VAMP1 interacts with STX1BProteinHetionet hetionet:interacts:112755-6843Inferred only
VAMP2 interacts with STX1BProteinHetionet hetionet:interacts:112755-6844Inferred only
VAMP8 interacts with STX1BProteinHetionet hetionet:interacts:112755-8673Inferred only
VAPB interacts with STX1BProteinHetionet hetionet:interacts:112755-9217Inferred only
STX1B participates in 15q11q13 copy number variationPathwayWikiPathways WP5407Inferred only
STX1B participates in Bacterial Infection PathwaysPathwayReactome R-HSA-9824439Inferred only
STX1B participates in Developmental BiologyPathwayReactome R-HSA-1266738Inferred only
STX1B participates in DiseasePathwayReactome R-HSA-1643685Inferred only

Show the remaining 16

STX1B participates in Infectious diseasePathwayReactome R-HSA-5663205Inferred only
STX1B participates in LGI-ADAM interactionsPathwayReactome R-HSA-5682910Inferred only
STX1B participates in Neurotoxicity of clostridium toxinsPathwayReactome R-HSA-168799Inferred only
STX1B participates in SNARE complex machinery in exocytosisPathwayWikiPathways WP5621Inferred only
STX1B participates in Synaptic vesicle pathwayPathwayWikiPathways WP2267Inferred only
STX1B participates in Toxicity of botulinum toxin type C (botC)PathwayReactome R-HSA-5250971Inferred only
STX1B participates in Uptake and actions of bacterial toxinsPathwayReactome R-HSA-5339562Inferred only
STX1B regulates negative regulation of macropinocytosisBiological processgene ontology P61266|GO:1905302Inferred only
STX1B regulates negative regulation of neuron projection developmentBiological processgene ontology P61266|GO:0010977Inferred only
STX1B regulates negative regulation of synaptic vesicle recyclingBiological processgene ontology P61266|GO:1903422Inferred only
STX1B regulates positive regulation of excitatory postsynaptic potentialBiological processgene ontology P61266|GO:2000463Inferred only
STX1B regulates positive regulation of neurotransmitter secretionBiological processgene ontology P61266|GO:0001956Inferred only
STX1B regulates positive regulation of spontaneous neurotransmitter secretionBiological processgene ontology P61266|GO:1904050Inferred only
STX1B regulates regulation of gene expressionBiological processgene ontology P61266|GO:0010468Inferred only
STX1B regulates regulation of synaptic activityBiological processgene ontology P61266|GO:0060025Inferred only
STX1B regulates regulation of synaptic vesicle primingBiological processgene ontology P61266|GO:0010807Inferred only

Other names

4 names

Resolves to: STX1B

Also called: STX1B1STX1B2Syntaxin-1B1Syntaxin-1B2

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