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Proteins/UNIPROT:P56962
SNAREs, soluble N-ethylmaleimide-sensitive factor-attachment protein receptors, are essential proteins for fusion of cellular membranes. SNAREs localized on opposing membranes assemble to form a trans-SNARE complex, an extended, parallel four alpha-helical bundle that drives membrane fusion. STX17 is a SNARE of the autophagosome involved in autophagy through the direct control of autophagosome membrane fusion with the lysosome membrane. May also play a role in the early secretory pathway where it may maintain the architecture of the endoplasmic reticulum-Golgi intermediate compartment/ERGIC and Golgi and/or regulate transport between the endoplasmic reticulum, the ERGIC and the Golgi..
Function from UniProtKB (P56962), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
13 statements
13 statements · 2 reference databases · Subject: STX17 · Sources: Hetionet, Reactome
1 name
Resolves to: STX17