Proteins/UNIPROT:P31391

SSTR4

ProteinUNIPROT:P31391

Receptor for somatostatin-14. The activity of this receptor is mediated by G proteins which inhibits adenylyl cyclase. It is functionally coupled not only to inhibition of adenylate cyclase, but also to activation of both arachidonate release and mitogen-activated protein (MAP) kinase cascade. Mediates antiproliferative action of somatostatin in tumor cells.

Function from UniProtKB (P31391), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Statements

16 statements

16 statements · 4 reference databases · Subject: SSTR4 · Sources: gene ontology, Hetionet, Reactome, WikiPathways

Order

SSTR4 covaries with CDH8ProteinHetionet hetionet:covaries:1006-6754Inferred only
MYO10 covaries with SSTR4ProteinHetionet hetionet:covaries:4651-6754Inferred only
SSTR4 covaries with POLR1DProteinHetionet hetionet:covaries:51082-6754Inferred only
SYBU covaries with SSTR4ProteinHetionet hetionet:covaries:55638-6754Inferred only
CORT interacts with SSTR4ProteinHetionet hetionet:interacts:1325-6754Inferred only
SST interacts with SSTR4ProteinHetionet hetionet:interacts:6750-6754Inferred only
SSTR4 participates in Class A/1 (Rhodopsin-like receptors)PathwayReactome R-HSA-373076Inferred only
SSTR4 participates in G alpha (i) signalling eventsPathwayReactome R-HSA-418594Inferred only
SSTR4 participates in GPCR downstream signallingPathwayReactome R-HSA-388396Inferred only
SSTR4 participates in GPCR ligand bindingPathwayReactome R-HSA-500792Inferred only
SSTR4 participates in GPCRs class A rhodopsin likePathwayWikiPathways WP455Inferred only
SSTR4 participates in Peptide GPCRsPathwayWikiPathways WP24Inferred only

Show the remaining 4

SSTR4 participates in Peptide ligand-binding receptorsPathwayReactome R-HSA-375276Inferred only
SSTR4 participates in Signal TransductionPathwayReactome R-HSA-162582Inferred only
SSTR4 participates in Signaling by GPCRPathwayReactome R-HSA-372790Inferred only
SSTR4 regulates negative regulation of cell population proliferationBiological processgene ontology P31391|GO:0008285Inferred only

Other names

4 names

Resolves to: SSTR4

Also called: SS-4-RSS4-RSS4RSST4

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