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Proteins/UNIPROT:Q9UMX9
Proton-associated glucose and sucrose transporter (By similarity). May be able to transport also fructose (By similarity). Expressed at a late melanosome maturation stage where functions as proton/glucose exporter which increase lumenal pH by decreasing glycolysis. Regulates melanogenesis by maintaining melanosome neutralization that is initially initiated by transient OCA2 and required for a proper function of the tyrosinase TYR..
Function from UniProtKB (Q9UMX9), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
1 row
10 statements
10 statements · 4 reference databases · Subject: SLC45A2 · Sources: Hetionet, Reactome, Rhea, WikiPathways
2 reactions
D-glucose+hydronD-glucose+hydron
Transported by SLC45A2 or SLC45A1
Reaction pageDirection not assertedBalanced
Rhea RHEA:69556CC BY 4.0Reference data
Transported by SLC45A3 or SLC45A2
Reaction pageDirection not assertedBalanced
5 names
Resolves to: SLC45A2