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Proteins/UNIPROT:Q00325
Inorganic ion transporter that transports phosphate or copper ions across the mitochondrial inner membrane into the matrix compartment (By similarity). Mediates proton-coupled symport of phosphate ions necessary for mitochondrial oxidative phosphorylation of ADP to ATP (By similarity). Transports copper ions probably in the form of anionic copper(I) complexes to maintain mitochondrial matrix copper pool and to supply copper for cytochrome C oxidase complex assembly. May also play a role in regulation of the mitochondrial permeability transition pore (mPTP) (By similarity)..
Function from UniProtKB (Q00325), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
2 rows
21 statements
21 statements · 3 reference databases · Subject: SLC25A3 · Sources: Hetionet, Human-GEM, Rhea
3 reactions
proton+phosphate(3-)proton+phosphate(3-)
Transported by SLC25A3
Reaction pageLeft to rightBalancedmitochondrial intermembrane space, cytosol, mitochondrial matrix
Human-GEM MAR05043CC BY 4.0Reference data
proton+phosphate(3-)proton+phosphate(3-)
Transported by SLC25A3
Reaction pageLeft to rightBalancedmitochondrial intermembrane space, mitochondrial matrix
4 names
Resolves to: SLC25A3
hydrogenphosphate+hydronhydrogenphosphate+hydron
Transported by SLC25A3
Reaction pageRight to leftBalanced
Rhea RHEA:29939CC BY 4.0Reference data